Adding Years: Your Roadmap to Longevity explores the cutting edge of health, performance, and anti-aging science. This podcast delivers expert insights, evidence based strategies, and practical tools to help you optimize your body, mind, and future. From longevity protocols and fitness to nutrition, supplements, and the role of AI in health, Adding Years provides the roadmap to live longer, stronger, and healthier.Disclaimer: This podcast is for informational purposes only and is not a substitute for professional medical advice.
The Future of Regenerative Medicine w/ Nabiha Saklayen, PhD
What if we could replace the cells we lose to aging and disease AND make those replacements from our own cells? Dr. Nabiha Saklayen, co-founder and CEO of Cellino, joins us on Adding Years to explore personalized regenerative medicine: the science behind it, the challenge of manufacturing it, and the evidence still needed to understand its potential.
In this episode we discuss:
• Preserving struggling cells versus replacing lost cells
• Yamanaka factors and induced pluripotent stem cells
• Genetics, gene editing, and the limits of an epigenetic reset
• The challenges of replacing cells in an aging body
• Autologous versus allogeneic cell therapies
• How AI and lasers support cell selection and manufacturing
• Manufacturing costs, access, and the vision of personalized cell banking
• Questions to ask when evaluating regenerative medicine claims
This conversation distinguishes today’s research and clinical development from the broader vision of widely accessible cell replacement. Subscribe for more conversations with researchers and innovators shaping the future of health and longevity.
The information provided in Adding Years: Your Roadmap to Longevity is for informational and educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. The hosts and producers are not licensed medical professionals, dietitians, or healthcare providers. While some guests or co-hosts may be licensed medical professionals, they appear solely in an educational capacity and are not providing individualized medical care or establishing any healthcare provider–patient relationship.
22 Sept 2026
Are We Asking The Wrong Questions About Longevity? W/ Dr. Jordan Shlain
What happens when we get the right answer to the wrong question? In this episode of Adding Years, Josie sits down with Dr. Jordan Shlain, physician, healthcare entrepreneur, and founder and chairman of Private Medical. Together, they explore:
• How to separate credible longevity science from a compelling sales pitch
• Why smart, successful people still fall for health and longevity hype
• Peptides, stem cells, exosomes, and interventions ahead of the evidence
• Why foundational health behaviors continue to matter
• Whether we’re measuring our health simply because we can
• When optimization creates more anxiety than benefit
• The difference between processing medical information and practicing medicine
• Where AI can strengthen healthcare—and where human judgment remains essential
• Why asking the right question may matter more than finding a fast answer
As Dr. Shlain explains, data does not interpret itself. The meaning of any number, test, or recommendation depends on the person, the context, and the question we are actually trying to answer. Are we using technology to make better health decisions—or are we simply finding more things to optimize?
The information provided in Adding Years: Your Roadmap to Longevity is for informational and educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. The hosts and producers are not licensed medical professionals, dietitians, or healthcare providers. While some guests or co-hosts may be licensed medical professionals, they appear solely in an educational capacity and are not providing individualized medical care or establishing any healthcare provider–patient relationship.
3 Sept 2026
Protein and Longevity: Are we getting it wrong?
Is more protein really better for healthy aging—or could eating less protein help us live longer? In this episode, Dr. Matt Kaeberlein joins me as co-host to examine some of the most debated and emerging areas of longevity science. Matt is a leading researcher in the biology of aging whose work has explored interventions that may improve healthspan and extend lifespan.
We explore:
• Whether high-protein diets are supported by longevity research • The potential tension between preserving muscle and extending lifespan
• Why the effects of protein depend on calories, diet quality, exercise and age
• What studies in mice can—and cannot—tell us about protein restriction in humans
• How specific amino acids interact with mTOR and other aging pathways
• What FGF21 is and why it may mediate some effects of protein restriction
• New research using FGF21 gene therapy to extend healthspan and lifespan in mice
• Whether existing interventions could offer similar benefits with less risk
• How Montana’s expanded Right to Try framework approaches experimental therapies
• The challenge of balancing patient access, scientific evidence and safety
Whether you’re focused on building muscle, improving metabolic health or living longer, this conversation offers a more nuanced way to think about protein—and a look at where longevity research may be heading next.
Read Lamming's paper: https://www.cell.com/cell-press-blue/fulltext/S3051-3839(26)00077-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS3051383926000770%3Fshowall%3Dtrue
Read about FGF21 gene therapy: https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(26)00469-7
Read Montana’s expanded Right to Try: https://montanabio.org/sb535-right-to-try-montana/
The information provided in Adding Years: Your Roadmap to Longevity is for informational and educational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. The hosts and producers are not licensed medical professionals, dietitians, or healthcare providers. While some guests or co-hosts may be licensed medical professionals, they appear solely in an educational capacity and are not providing individualized medical care or establishing any healthcare provider–patient relationship.
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