A podcast about the science of how AI works and the art of using AI to reimagine your life, business, and society! Hosted by Nikhil Maddirala (AI Product Manager) and Piyush Agarwal (AI Sales Executive), bringing you their expertise from world’s leading AI companies.

Art and Science of AI
Claim This Podcastby Nikhil Maddirala and Piyush Agarwal
Podcast Overview
A podcast about the science of how AI works and the art of using AI to reimagine your life, business, and society! Hosted by Nikhil Maddirala (AI Product Manager) and Piyush Agarwal (AI Sales Executive), bringing you their expertise from world’s leading AI companies.
Language
🇺🇲
Publishing Since
6/8/2024
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Recent Episodes

June 5, 2026
S3-E1: Why We Love the Codex Desktop App
<p>We kick off season 3 with a conversation about what makes the Codex Desktop app compelling as an AI workspace. Nikhil and Piyush break down the idea of an AI harness, why heartbeat automations matter, how shared browser context changes the feedback loop, and why moving beyond terminal-first workflows makes AI feel more usable for everyday work. The episode also explores how Codex is shifting from a developer-focused tool toward a broader end-user productivity platform, and why trust, identity, and safety become more important as AI agents get more capable and more persistent.</p><p>= ⏰ CHAPTERS =<br>00:10: Introduction: Season 3 Kickoff<br>01:23: How We Both Became Codex Converts<br>08:23: What Is an AI Harness?<br>12:36: Codex as Your Second Brain<br>17:28: Heartbeat Automations Explained<br>22:08: Why I Switched from the Terminal to the Desktop App<br>35:40: Security and Identity in AI Agents<br>41:36: Levels of Autonomy: A Framework for Trusting AI</p><p><br></p><p>= 🧠 KEY CONCEPTS =</p><ul><li>AI harnesses: The surrounding system that shapes how effectively a model can act.</li><li>Codex as a second brain: Why persistent context and integrated tools make the app feel like an assistant, not just a chat box.</li><li>Heartbeat automations: Repeated runs that build on prior state instead of resetting every time.</li><li>Desktop workflows: How shared browser context and visible tool use improve the feedback loop.</li><li>Trust and autonomy: Why security, identity, and human oversight matter as agents become more capable.</li><li>End-user productivity: How Codex is moving from developer tooling toward everyday usefulness.</li></ul><p><br></p><p>= 💬 KEYWORDS =<br><a href="#AI">#AI</a> <a href="#Codex">#Codex</a> <a href="#OpenAI">#OpenAI</a> <a href="#AIAgents">#AIAgents</a> <a href="#AIAutomation">#AIAutomation</a> <a href="#HarnessEngineering">#HarnessEngineering</a> <a href="#HeartbeatAutomations">#HeartbeatAutomations</a> <a href="#Productivity">#Productivity</a> <a href="#AItools">#AItools</a> <a href="#Podcast">#Podcast</a></p>

October 31, 2024
S2-E10: Building the “self-driving car” of digital advertising: how to drive profit with AI in advertising
<p>Nikhil and Piyush discuss the evolution of digital advertising and the transformative role of AI. We explore the shift from traditional advertising to the sophisticated AI-driven campaigns of today, and how AI has enabled companies like Airbnb to turn advertising from a cost center into a profit making machine. We discuss the importance of measurement and profitability, and how AI is automating sophisticated targeting and bidding strategies to help businesses grow profitably. </p> <p><br /></p> <p>=== ⏰ CHAPTERS ===</p> <p>00:00: Introduction to digital advertising</p> <p>06:19: The evolution of advertising: from traditional to digital</p> <p>29:56: How Airbnb turned advertising into a profit center</p> <p>50:55: Self-driving AI advertising to optimize for profit</p> <p><br /></p> <p>=== 🧠 KEY CONCEPTS ===</p> <p>- Traditional vs. Digital Advertising: The early days of digital marketing replicated traditional advertising models with digital banners and impressions. AI is now transforming these strategies by optimizing for actual conversions and profit, eliminating much of the guesswork.</p> <p>- AI-Powered Advertising: Google and Meta’s AI platforms are making sophisticated marketing accessible by automating complex processes like bidding, targeting, and creative generation, allowing advertisers to focus on profit-driven goals.</p> <p>- From Impressions to Conversions: Businesses can now optimize directly for conversions and profit, turning digital marketing into a money-printing machine rather than a cost center.</p> <p>- Key Metrics and Strategy: The most advanced advertising programs are now focusing on maximizing contribution margin (profitability per product), using advanced tracking and AI-powered optimization.</p> <p>- Incrementality and Attribution: With tools like incrementality testing, businesses can scientifically measure the true impact of their advertising spend, ensuring they allocate budgets efficiently and profitably.</p> <p><br /></p> <p>=== 🔗 LINKS ===</p> <p>- Homepage: https://artscienceai.substack.com/about</p> <p>- YouTube: https://www.youtube.com/@ArtScience-AI</p> <p>- Spotify: https://podcasters.spotify.com/pod/show/art-science-ai</p> <p>- Linkedin: https://www.linkedin.com/company/art-science-ai</p> <p>- Facebook: https://www.facebook.com/ArtScienceAI</p> <p>- Instagram: http://instagram.com/artscienceai/</p> <p>- Threads: https://www.threads.net/@artscienceai</p> <p>- Twitter / X: https://x.com/ArtScienceAI</p> <p><br /></p> <p>=== 💬 KEYWORDS ===</p> <p>#AI #GenAI #LLM #ChatGPT #podcast</p>

August 27, 2024
S2-E9: Google AI announcements and legal challenges
<p>In this episode Nikhil and Piyush discuss Google's recent AI announcements from the Google Pixel event and the recent antitrust ruling in the US declaring Google to be a monopolist. We discuss new AI capabilities in Google Pixel such as Gemini Live, multimodal AI, and the challenges of integrating LLMs into AI assistants. We then discuss the Google antitrust ruling and its implications for Google and Apple. The conversation also touches on the power dynamics of big tech companies, the future potential of AI to expand human sensory consciousness and the implications for AGI!</p> <p><br /></p> <p>=== ⏰ CHAPTERS ===</p> <p>- 00:00 Google Pixel event: AI features & Gemini</p> <p>- 07:25 Google Gemini vs. Apple Intelligence</p> <p>- 27:55 Google antitrust ruling</p> <p>- 46:54 Future of AI: tech giants vs. startups</p> <p><br /></p> <p>=== 🧠 KEY CONCEPTS ===</p> <p>- AI in Google Pixel: Google announced the launch of new Pixel phones with AI features centered around Gemini Live. However, there was no mention of any third-party app integrations that were announced in Apple Intelligence.</p> <p>- Gemini Live: Gemini Live allows real-time interaction with the Google AI model, combining voice input with access to the camera, screen, and app information. </p> <p>- Multimodal AI: Integrating different modalities, such as text, image, audio, and video, into AI models is a complex challenge that researchers are working on. The ultimate goal is to develop multimodal models that can process and generate information in various formats, similar to human sensory consciousness.</p> <p>- Google's monopoly status: A US judge ruled that Google is a monopolist in an antitrust case, which has implications for Google, Apple, and raises questions about the power dynamics of big tech companies and the future of AI.</p> <p><br /></p> <p>=== 🔗 LINKS ===</p> <p>- Homepage: https://artscienceai.substack.com/about</p> <p>- YouTube: https://www.youtube.com/@ArtScience-AI</p> <p>- Spotify: https://podcasters.spotify.com/pod/show/art-science-ai</p> <p>- Linkedin: https://www.linkedin.com/company/art-science-ai</p> <p>- Facebook: https://www.facebook.com/ArtScienceAI</p> <p>- Instagram: http://instagram.com/artscienceai/</p> <p>- Threads: https://www.threads.net/@artscienceai</p> <p>- Twitter / X: https://x.com/ArtScienceAI</p> <p><br /></p> <p>=== 💬 KEYWORDS ===</p> <p>#AI #GenAI #LLM #ChatGPT #podcast</p>
18 total episodes available
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