AudioHelicase, the podcast of Whitehead Institute: Unwinding the science and the people behind some of the Institute’s most exciting discoveries. Whitehead Institute is a world-renowned non-profit research institution dedicated to improving human health through basic biomedical research. By cultivating a deeply collaborative culture and enabling the pursuit of bold, creative inquiry, Whitehead fosters paradigm-shifting scientific achievement. For more than 30 years, Whitehead faculty have delivered breakthroughs that have transformed our understanding of biology and accelerated development of therapies for such diseases as Alzheimer’s, Parkinson’s, diabetes, and certain cancers.
AudioHelicase Special: When cells are in their element
Host Shafaq Zia interviews Whitehead Institute researchers about how studying biological processes in their natural environment yields unique insights into regeneration, organ function, immune response, and embryonic development.
25 Mar 2024
AudioHelicase Special: How foundational research takes medicines from lab to shelf
In this episode of AudioHelicase, we sit down with three Whitehead Institute researchers driving breakthroughs in disease treatment. Join us as we explore some of the toughest challenges they’re overcoming to move transformative therapies from lab bench to your medicine cabinet. Credits: Interviews, production, and hosting by Shafaq Zia. Music and sound effects: Crescent Bloom … Continue reading AudioHelicase Special: How foundational research takes medicines from lab to shelf → (https://audiohelicase.blubrry.net/2024/03/25/audiohelicase-special-whitehead-institute-researchers-on-drug-development/)
3 Apr 2023
AudioHelicase Special: Getting a handle on hibernation
Whitehead Institute Member Siniša Hrvatin discusses his research on the neuroscience of hibernation.
19 May 2021
AudioHelicase Special: RNA in health and disease
Whitehead Institute researchers Silvi Rouskin, Ankur Jain, and David Bartel discuss how their RNA research connects to health and disease, including viral infections and neurodegeneration. This podcast is part of a multimedia series on RNA.
8 Feb 2021
AudioHelicase Special: Rebuilding a Body
In this special episode of AudioHelicase, we talk to three researchers about the cells in our bodies that can regenerate – and those that can’t. We ask, why can some cells no longer renew themselves? And, importantly, can we change that? This podcast is part of our multimedia series, Cells Over Time.
2 Dec 2020
AudioHelicase Special: How researchers at Whitehead Institute are building a more sustainable future
Making our world more sustainable to preserve it for future generations will take not just one but many solutions. Researchers at Whitehead Institute are exploring how the natural world could teach us how to improve the sustainability of how we produce food, how we make medicines, how we make products more durable, and potentially how … Continue reading AudioHelicase Special: How researchers at Whitehead Institute are building a more sustainable future → (https://audiohelicase.blubrry.net/2020/12/02/audiohelicase-special-how-researchers-at-whitehead-institute-are-building-a-more-sustainable-future/)
13 Oct 2020
Whitehead Institute’s Silvi Rouskin on solving the structure of the coronavirus genome
In this episode of AudioHelicase Podcast, Whitehead Fellow Silvi Rouskin discusses her research on solving the structure of the novel coronavirus’s RNA genome, with the goal of revealing weak points in the virus’s gene regulation that new drugs could potentially target. Music: “Versailles” by Pierce Murphy (CC-BY 4.0). Produced by Conor Gearin.
3 Aug 2020
Whitehead Institute’s Olivia Corradin on a New Way to Probe Disease Genetics
On this episode of AudioHelicase podcast, Whitehead Fellow Olivia Corradin talked about investigating the genetic underpinnings of diseases through a new technique she developed, the outside variant approach. Applying the method to study the autoimmune disease multiple sclerosis (MS), Corradin and colleagues identified a role for a cell type in the brain in MS, offering … Continue reading Whitehead Institute’s Olivia Corradin on a New Way to Probe Disease Genetics → (https://audiohelicase.blubrry.net/2020/08/03/whitehead-institutes-olivia-corradin-on-a-new-way-to-probe-disease-genetics/)
8 Jun 2020
Whitehead’s Jing-Ke Weng on COVID-19 treatments taking root in plant science
Plants have been used as medicine for thousands of years; could they contribute to a solution to the COVID-19 pandemic? This is what Whitehead Institute Member Jing-Ke-Weng set out to address in a new paper, published May 20 in the journal Molecular Plant. We talked to Weng about an herbal treatment being used to treat … Continue reading Whitehead’s Jing-Ke Weng on COVID-19 treatments taking root in plant science → (https://audiohelicase.blubrry.net/2020/06/08/whiteheads-jing-ke-weng-on-covid-19-treatments-taking-root-in-plant-science/)
18 Mar 2020
AudioHelicase Special: The Conductors of the Cell’s Symphony
In this special episode of AudioHelicase podcast, we’re taking a look at how our researchers are identifying the key players that help conduct the cell’s symphony — the proteins and molecules that direct many other parts of the cell on when and how to do their jobs. The episode features highlights from interviews with Whitehead … Continue reading AudioHelicase Special: The Conductors of the Cell’s Symphony → (https://audiohelicase.blubrry.net/2020/03/18/audiohelicase-special-the-conductors-of-the-cells-symphony/)
10 Feb 2020
Whitehead Institute’s Pulin Li on creating multicellular patterns in a Petri dish
In this episode of AudioHelicase, Whitehead Institute Member Pulin Li talks about how her lab engineers cells in Petri dishes to communicate with each other and form patterns, recreating processes seen in embryo development—and how this work could eventually inform efforts to grow tissues in the lab. Produced by Conor Gearin Music: Pierce Murphy, … Continue reading Whitehead Institute’s Pulin Li on creating multicellular patterns in a Petri dish → (https://audiohelicase.blubrry.net/2020/02/10/whitehead-institutes-pulin-li-on-creating-multicellular-patterns-in-a-petri-dish/)
19 Feb 2019
Whitehead Institute’s Ankur Jain on RNA clumps and the neurodegenerative diseases they are associated with
In this episode of AudioHelicase, Whitehead Institute Member Ankur Jain discusses how RNA can clump in cells and the diseases, such as Huntington's and amyotrophic lateral sclerosis (ALS), that are associated with these aggregations.
21 May 2018
Whitehead’s Iain Cheeseman discusses cell division and what can happen when it goes wrong
In this episode of AudioHelicase, Whitehead Institute Member Iain Cheeseman discusses how his work on the kinetochore provides a window into cell division and what happens when this vital cellular function goes awry.
11 Apr 2018
Whitehead’s Mary Gehring discusses how gene regulation can be passed from one generation to the next
In this episode of AudioHelicase, Whitehead Institute Member Mary Gehring discusses how her research on the plant Arabidopsis thaliana reveals how gene regulation can be passed from one generation to the next.
22 Jan 2018
Whitehead’s Robert Weinberg on cancer research’s past, present, and future
From his discovery of the first oncogene and tumor suppressor, to his work revealing critical aspects of the mutational basis of cancer, and more recently its metastatic behavior, Whitehead Founding Member Robert Weinberg’s work has been foundational in our understanding of cancer biology.
21 Nov 2017
Whitehead’s Sebastian Lourido on Toxoplasma, malaria parasites, and global health
Whitehead Member Sebastian Lourido studies a group of parasites called the Apicomplexa. These single-celled organisms are among the most common pathogens and are capable of causing devastating diseases in humans and animals, including toxoplasmosis, malaria, and infant diarrhea. Lourido's laboratory is investigating in particular how the Apicomplexan Toxoplasma gondii invades host cells and establishes its site of replication. The work holds great promise for exposing treatable vulnerabilities in the parasite—and in the closely related Plasmodium parasites, which cause malaria and contribute to more than half a million deaths each year.
23 Oct 2017
NASA’s Kathleen “Kate” Rubins on her journey from studying pox viruses to sequencing DNA in space
NASA Astronaut and Former Whitehead Fellow Kathleen "Kate" Rubins sits down with Whitehead's Director David Page to discuss her journey from studying pox viruses to sequencing DNA in space.
12 Sept 2017
Whitehead’s David Sabatini discusses mTOR, a protein connecting metabolism, nutrition, and disease
As a graduate student, Whitehead Member David Sabatini identified mTOR, the keystone molecule in a cellular pathway connecting nutrition, metabolism, and aging. In this episode, he discusses how the molecule was first discovered and what his lab is currently working on, including mTOR’s role in cancer, growth, and metabolism.
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3 ratings
Podcast Authority Score: 20 / 100
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Engagement
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