Critical Care — a weekly podcast briefing of the most significant peer-reviewed critical care literature, synthesized from PubMed and delivered as ~10-minute audio. For practicing physicians. Generated by AudioScholar at audioscholar.cc.
Editor's Pick: Delay From Hypotension Onset to Appropriate Antifungal Therapy Initiation Is the Critical Determinant of Outcome in Candida Septic Shock (Critical Care Medicine, 2026)
This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice.
Welcome to This Week in Critical Care. This week we're covering 10 notable papers spanning shock and haemodynamic monitoring, the airway and liberation from mechanical ventilation, and the bedside tools and frameworks that shape everyday ICU care.
This week's papers:
1. Delay From Hypotension Onset to Appropriate Antifungal Therapy Initiation Is the Critical Determinant of Outcome in Candida Septic Shock. — Critical Care Medicine 2026
2. Heterogeneous cardiovascular responses to acute mean arterial pressure augmentation in septic shock: the role of ventriculo-arterial coupling and venous return. — Critical Care 2026
3. Brachial-to-Radial Pressure Gradient in Critically Ill Patients Treated With Vasoactive Agents: A Prospective Observational Study. — Critical Care Medicine 2026
4. Comparative Analysis of Tracheal Intubation-Associated Cardiac Arrest in 2015-2023: A Report From the National Emergency Airway Registry for Children Multicent… — Critical Care Medicine 2026
5. Association of Acute Respiratory Distress Syndrome Radiographic Findings Identified by Machine Learning and Outcomes of Patients Receiving Invasive Mechanical… — Critical Care Medicine 2026
6. Toward targeted assessment of inspiratory muscle weakness before extubation: a pooled individual patient data analysis from multiple observational cohorts in c… — Critical Care 2026
7. Music Therapy During Weaning From Invasive Mechanical Ventilation in the ICU: A Randomized Controlled Trial. — Critical Care Medicine 2026
8. Furosemide Stress Test in Adults and Children With Acute Kidney Injury: A Systematic Review and Meta-Analysis. — Critical Care Medicine 2026
9. Principles of drug dosing for obese patients in the intensive care unit. — Intensive Care Medicine 2026
10. European Society of Intensive Care Medicine consensus statement on human-centred partnership in the intensive care unit. — Intensive Care Medicine 2026
Listen at https://audioscholar.cc/episode/v5bnvqe7c5
21 Oct 2026
This Week in Critical Care — Oct 21, 2026
This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice.
Welcome to This Week in Critical Care. This week we're covering 10 notable papers spanning haemodynamic managemen…
This week's papers:
1. Effect of Vasopressin Initiation Threshold on Septic Shock Mortality: The VASSPR Cluster Crossover Randomized Strategy Trial. — JAMA 2026
2. Intraoperative Dobutamine Plus Norepinephrine to Prevent Postoperative Acute Kidney Injury in Septic Shock: A Randomized Clinical Trial. — JAMA 2026
3. What every intensivist should know about dynamic left ventricular outflow tract obstruction. — Journal of Critical Care 2026
4. Guidelines for the management of atrial fibrillation in adult patients admitted to an intensive care unit. — Annals of Intensive Care 2026
5. Isoflurane-Based Inhaled Sedation in Mechanically Ventilated Adults With Acute Hypoxemic Respiratory Failure: The SAVE-ICU Randomized Clinical Trial. — JAMA 2026
6. Open Visiting Policy and Delirium in Adult Patients in ICUs: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. — Critical Care Medicine 2026
7. Weaning Strategies for High-Flow Nasal Cannula in Critically Ill Adults: A Randomized Clinical Trial. — Critical Care Medicine 2026
8. Permissive versus conventional weaning from venovenous ECMO in patients with ARDS: a retrospective cohort study. — Annals of Intensive Care 2026
9. Fluid Therapy in Mechanically Ventilated Critically Ill Adult Patients. — JAMA 2026
10. Association of Oliguria With Acute Kidney Injury, Chronic Kidney Disease, and Mortality: Determining the Optimal Threshold in Critically Ill Patients. — Critical Care Medicine 2026
Listen at https://audioscholar.cc/episode/tgvuap6veq
14 Oct 2026
This Week in Critical Care — Oct 14, 2026
This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice.
Welcome to This Week in Critical Care. This week we're covering 10 notable papers spanning sepsis therapies from…
This week's papers:
1. Polymyxin B hemoadsorption in endotoxic septic shock: ten questions on the Tigris trial. — Critical Care 2026
2. The effects of hemoadsorption in patients with sepsis-associated persistent severe AKI who require CRRT: A prospective, randomized controlled pilot study. — Annals of Intensive Care 2026
3. Individualized Treatment Effects of Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized with Acute Infection. — American Journal of Respiratory and Critical Care Medicine 2026
4. Early piperacillin exposure during continuous infusion in critically ill patients: the impact of renal and liver dysfunctions. — Annals of Intensive Care 2026
5. Comparative Effectiveness of Phenobarbital vs Diazepam for Alcohol Withdrawal Syndrome. — JAMA Internal Medicine 2026
6. Effectiveness of Continuous Automatic Endotracheal Cuff Pressure Monitoring in Preventing Ventilator-Associated Pneumonia in the Pediatric Intensive Care Unit:… — Chest 2026
7. Prophylactic high-flow nasal oxygen vs. conventional oxygen for prevention of postoperative respiratory complications: a randomized trial. — Critical Care 2026
8. Mechanical versus manual bag-valve ventilation during cardiopulmonary resuscitation in adults with cardiac arrest: A systematic review and Bayesian meta-analys… — Resuscitation 2026
9. Early Post-ROSC Laboratory Phenotypes and Clinical Outcomes after Out-of-Hospital Cardiac Arrest: A 10-Year National Cohort Study. — Resuscitation 2026
10. Fibrinolytic Activation and Its Association with Mortality After Traumatic and Thermal Injury. — Shock 2026
Listen at https://audioscholar.cc/episode/8q9uwnbuud
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