Psychiatry — a weekly podcast briefing of the most significant peer-reviewed psychiatry literature, synthesized from PubMed and delivered as ~10-minute audio. For practicing physicians. Generated by AudioScholar at audioscholar.cc.
Editor's Pick: Single Intranasal Administration of the Psychedelic Mebufotenin for Treatment-Resistant Depression: A Randomized Clinical Trial (JAMA, 2026)
This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice.
Welcome to This Week in Psychiatry. This week we're covering 10 notable papers spanning new approaches to depression and acute trauma, the long arc of schizophrenia treatment, and a set of sobering negative and reframing findings in suicide preventio…
This week's papers:
1. Single Intranasal Administration of the Psychedelic Mebufotenin for Treatment-Resistant Depression: A Randomized Clinical Trial. — JAMA 2026
2. Preoperative Intranasal Oxytocin and Probable Acute Stress Disorder After Traumatic Fracture Surgery: A Randomized Clinical Trial. — JAMA Internal Medicine 2026
3. The Unbroken Integrative Psycho-Trauma Care Model: Health System Implementation in Wartime Ukraine. — JAMA Psychiatry 2026
4. Real-world associations of antipsychotic use with clinical outcomes in schizophrenia: a systematic review and meta-analysis. — Molecular Psychiatry 2026
5. Clozapine Augmentation Strategies and Clinical Predictors of Prolonged Tertiary Hospitalization in Clozapine-Resistant Schizophrenia: a Retrospective Cohort St… — Schizophrenia Bulletin 2026
6. Efficacy of Personalizing Cognitive Remediation for Schizophrenia by Targeting Impairments in Early Auditory Processing. — Schizophrenia Bulletin 2026
7. Instrumental Support Calls vs. Caring Contacts Texts to Prevent Suicide in Adolescents and Adults: The SPARC Randomized Clinical Trial. — American Journal of Psychiatry 2026
8. Prefrontal Cortical Changes With Mindfulness-Oriented Recovery Enhancement in Opioid Use Disorder: A Randomized Clinical Trial. — JAMA Psychiatry 2026
9. Effects of External Trigeminal Nerve Stimulation on Neurocognitive Functioning in Children and Adolescents With ADHD: A Phase 2b Multicenter Randomized Control… — American Journal of Psychiatry 2026
10. Trends in Autism Spectrum Disorder Cumulative Incidence and Incidence Density: A Systematic Review. — Biological Psychiatry 2026
Listen at https://audioscholar.cc/episode/dw56kvtyfe
26 Oct 2026
This Week in Psychiatry — Oct 26, 2026
Editor's Pick: Metabolic biomarker levels before and after initiation of GLP-1 receptor agonist treatment among individuals with schizophrenia: interrupted time-series analysis (British Journal of Psychiatry, 2026)
This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice.
Welcome to This Week in Psychiatry. This week we're covering 10 notable papers spanning prediction and subtyping in depression, metabolic care and circuit biology in schizophrenia, and the experiences of families after psychiatric assisted dying.
This week's papers:
1. Multimodal Machine Learning-Based Prediction of Relapse in Major Depressive Disorder. — JAMA Psychiatry 2026
2. Clinical and genetic correlates of a circadian subtype of depression in the Australian Genetics of Depression Study. — British Journal of Psychiatry 2026
3. Shared cortical morphometry and molecular signatures across depression and physical diseases. — Molecular Psychiatry 2026
4. Repetitive transcranial magnetic stimulation (rTMS) combined with antidepressant pharmacotherapy for depression: state-dependent mechanisms, clinical evidence,… — Molecular Psychiatry 2026
5. Metabolic biomarker levels before and after initiation of GLP-1 receptor agonist treatment among individuals with schizophrenia: interrupted time-series analys… — British Journal of Psychiatry 2026
6. Simultaneous measurement of Midbrain and Striatal Dopamine in Schizophrenia using an agonist radiotracer. — Biological Psychiatry 2026
7. Thalamocortical dysconnectivity shapes cortical hierarchy disruption across illness durations in schizophrenia. — Biological Psychiatry 2026
8. Positive-affective and negative-cognitive brain-behavior axes in clinical high risk for psychosis. — Biological Psychiatry 2026
9. From Protective Factors to Mechanisms: Charting the Neurobiology of Schizophrenia Resilience. — Schizophrenia Bulletin 2026
10. Medical assistance in dying on psychiatric versus somatic grounds: survey on the experiences of relatives. — British Journal of Psychiatry 2026
Listen at https://audioscholar.cc/episode/q3nhxpfc8e
19 Oct 2026
This Week in Psychiatry — Oct 19, 2026
This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice.
Welcome to This Week in Psychiatry. This week we're covering 10 notable papers spanning treatment options for dep…
This week's papers:
1. Effectiveness of rTMS vs. Pharmacotherapy in Late-Life Treatment-Resistant Depression: An Observational Study of Individual Participant Data From Two Randomize… — American Journal of Psychiatry 2026
2. Long-term effectiveness of transdiagnostic cognitive-behavioural therapy for anxiety and depression in primary care: the PsicAP-CV trial. — Psychotherapy and Psychosomatics 2026
3. Computerized Cognitive Training in People with Depression: A Systematic Review and Meta-analysis of Randomized Clinical Trials. — Psychotherapy and Psychosomatics 2026
4. Change in HbA1c and weight after initiation of antipsychotic treatment in people with severe mental illness in England: an individual-level interrupted time-se… — The Lancet Psychiatry 2026
5. GLP-1 receptor agonist initiation and risk of psychiatric hospitalisation and emergency department presentation in adults with schizophrenia and type 2 diabete… — The Lancet Psychiatry 2026
6. Caring Letters and Suicide Mortality Among US Veterans Who Contacted the Veterans Crisis Line: A Prespecified Secondary Analysis. — JAMA Psychiatry 2026
7. Genetic architecture and risk of suicide attempt across neurodevelopmental and psychiatric conditions. — Biological Psychiatry 2026
8. Long-term health, criminal justice, and socioeconomic outcomes among people subject to compulsory mental health care in Norway: a nationwide registry cohort st… — The Lancet Psychiatry 2026
9. Adult Attention Deficit-Hyperactivity Disorder. — New England Journal of Medicine 2026
10. Attention deficit hyperactivity disorder: transition to psychotic disorders. — Molecular Psychiatry 2026
Listen at https://audioscholar.cc/episode/5s3rpqaeab
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