Pulmonary — a weekly podcast briefing of the most significant peer-reviewed pulmonary literature, synthesized from PubMed and delivered as ~10-minute audio. For practicing physicians. Generated by AudioScholar at audioscholar.cc.
Editor's Pick: Prone positioning and high-frequency oscillatory ventilation in early paediatric acute respiratory distress syndrome (PROSpect): an international, two-by-two factorial, response-adaptive, phase 3, randomised controlled trial (The Lancet, 2026)
This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice.
Welcome to This Week in Pulmonary. This week we're covering 10 notable papers spanning critical care and transplant, airway disease and its infections, and thoracic oncology and care delivery. Let's dive in.
This week's papers:
1. Prone positioning and high-frequency oscillatory ventilation in early paediatric acute respiratory distress syndrome (PROSpect): an international, two-by-two f… — The Lancet 2026
2. Extracorporeal membrane oxygenation as rescue therapy for patients with suspected high-risk pulmonary embolism: A multicenter retrospective cohort study. — Respiratory Medicine 2026
3. Lung Allograft Function After Primary Graft Dysfunction in the Lung Transplant Outcomes Group Cohort. — American Journal of Respiratory and Critical Care Medicine 2026
4. Dupilumab is associated with improved lung functions in patients with COPD and type 2 inflammation: a post hoc analysis of the BOREAS and NOTUS trials. — American Journal of Respiratory and Critical Care Medicine 2026
5. Actionable Biomarkers in Acute Exacerbations of COPD: Corticosteroid and Antibiotic Stewardship. — International Journal of Chronic Obstructive Pulmonary Disease 2026
6. Azithromycin Exposure and Incident Nontuberculous Mycobacterial Isolation in Bronchiectasis and COPD: A Nationwide Nested Case-Control Study. — Chest 2026
7. The natural history of Mycobacterium abscessus in cystic fibrosis and the impact of elexacaftor/tezacaftor/ivacaftor. — Respiratory Medicine 2026
8. Subspecialty ILD Clinic Care is Associated with More Guideline-Concordant Evaluation and Improved Outcomes Compared to Other Ambulatory Settings: A Retrospecti… — Chest 2026
9. Brief Report: Patterns of Disease Progression with Durvalumab versus Placebo After Concurrent Chemoradiotherapy for Limited-Stage SCLC in the Phase 3 ADRIATIC… — Journal of Thoracic Oncology 2026
10. Neoadjuvant durvalumab plus chemotherapy in resectable or borderline resectable non-small-cell lung cancer: the phase 2 MDT-BRIDGE trial. — Nature Medicine 2026
Listen at https://audioscholar.cc/episode/jbxzbr4rw3
27 Oct 2026
This Week in Pulmonary — Oct 27, 2026
Editor's Pick: Tarlatamab-Durvalumab Maintenance for Extensive-Stage Small-Cell Lung Cancer (New England Journal of Medicine, 2026)
This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice.
Welcome to This Week in Pulmonary. This week we're covering 10 notable papers spanning a wave of phase 3 thoracic oncology trials, eosinophilic airway and vasculitic disease, and practical questions in infection and acute pulmonary embolism.
This week's papers:
1. Tarlatamab-Durvalumab Maintenance for Extensive-Stage Small-Cell Lung Cancer. — New England Journal of Medicine 2026
2. Divarasib as Compared with Sotorasib or Adagrasib in KRAS G12C-Mutated NSCLC. — New England Journal of Medicine 2026
3. Osimertinib-Savolitinib in Advanced NSCLC after Progression during EGFR-TKI Therapy. — New England Journal of Medicine 2026
4. Izalontamab brengitecan versus platinum-based chemotherapy in EGFR-mutated advanced non-squamous non-small-cell lung cancer after progression on third-generati… — The Lancet 2026
5. Ruzaltatug rezetecan versus chemotherapy for EGFR-mutated advanced non-small-cell lung cancer progressing after EGFR tyrosine kinase inhibitor therapy (HERON-L… — The Lancet 2026
6. Sacituzumab Tirumotecan plus Pembrolizumab in PD-L1-Negative Advanced NSCLC. — New England Journal of Medicine 2026
7. Rituximab vs Azathioprine for Eosinophilic Granulomatosis With Polyangiitis Maintenance Therapy: A Randomized Clinical Trial. — JAMA 2026
8. Real-World Impact of Mepolizumab in COPD in a US Commercial and Medicare Claims Database. — International Journal of Chronic Obstructive Pulmonary Disease 2026
9. Cavitary status and differential treatment response in refractory or severe Mycobacterium avium complex pulmonary disease: Amikacin liposome inhalation suspens… — Respiratory Medicine 2026
10. Low end-tidal carbon dioxide identifies high-severity pulmonary embolism and shock-level haemodynamics. — ERJ Open Research 2026
Listen at https://audioscholar.cc/episode/fqqcpfwyv3
20 Oct 2026
This Week in Pulmonary — Oct 20, 2026
This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice.
Welcome to This Week in Pulmonary. This week we're covering 10 notable papers spanning acute respiratory failure…
This week's papers:
1. Isoflurane-Based Inhaled Sedation in Mechanically Ventilated Adults With Acute Hypoxemic Respiratory Failure: The SAVE-ICU Randomized Clinical Trial. — JAMA 2026
2. High-Frequency Chest Wall Oscillation in Acute Respiratory Failure With Bronchial Hypersecretion: A Randomized Controlled Trial. — Chest 2026
3. The Prognostic Value of PaCO2 on the Response to Noninvasive Ventilation in Patients with AECOPD Complicated by Type II Respiratory Failure. — International Journal of Chronic Obstructive Pulmonary Disease 2026
4. Association of inhaled corticosteroid use with first Pseudomonas aeruginosa isolation in eosinophilic bronchiectasis: a multicenter retrospective study. — Respiratory Medicine 2026
5. Fertility, pregnancy, and women's health in bronchiectasis: a multicenter study and ELF-EMBARC patient survey. — Chest 2026
6. Safety and diagnostic yield of transbronchial lung cryobiopsy in patients with interstitial lung disease and severe pulmonary function impairment. — Respiratory Research 2026
7. Effect of clarithromycin on the circulating inflammatory proteome in community-acquired pneumonia: a secondary analysis of the ACCESS trial. — Chest 2026
8. Epidemiology, risk factors and clinical outcome of community-acquired pneumonia in severely immunosuppressed patients: a comprehensive analysis from the multin… — ERJ Open Research 2026
9. A phase 2a study with SPL84: A novel RNA-targeted approach to restore CFTR function in people with CF carrying the 3849+10 kb C→T mutation. — European Respiratory Journal 2026
10. Multimodal investigation of the association between bevacizumab and pulmonary arterial hypertension. — ERJ Open Research 2026
Listen at https://audioscholar.cc/episode/8kcqdduvun
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