Biopeak Live - Longevity India Podcast

About Biopeak Live - Longevity India Podcast

The Biopeak Live podcast by Longevity India, jointly hosted by Mr. Prashanth Prakash, Founding Patron of Longevity India; Founding Partner at Accel India and Prof. Deepak Saini, Convener of Longevity India at the Indian Institute of Science, features insightful discussions on health and longevity with an India-centric narrative. Our mission is to promote awareness on healthy aging via science-backed conversations with global experts, especially as the aging population continues to grow in India and worldwide. This podcast is presented by Longevity India and Biopeak.

Publisher

Longevity India

Category

health & fitness

Language

en

Explicit

No

First episode

14 Apr 2025

Latest episode

26 May 2026

Latest episodes

11 episodes in the feed.

1. 

   26 May 2026

   Rapamycin, Biological Clocks & the Future of Longevity | Matt Kaeberlein

   In this episode of Biopeak Live, hosts Prof Deepak Saini and Mr Prashanth Prakash are joined by Prof Matt Kaeberlein for a wide-ranging conversation on the current state and future of longevity science.Matt reflects on his journey from academia into entrepreneurship and the challenges that shaped projects like the Dog Aging Project and Ora BiomedicalThe discussion explores mTOR biology, Rapamycin, caloric restriction, biological clocks, AI-driven discovery, and the limitations of the “hallmarks of aging” framework.Matt also shares his views on supplement hype, the promise and pitfalls of biological age testing, and why large-scale unbiased discovery science may be key to unlocking the next era of longevity research.Timestamps00:00 – Introduction01:03 – Matt Kaeberlein’s journey into aging research04:09 – Early aging biology research06:47 – Academia vs startups11:31 – mTOR and Rapamycin14:37 – Hallmarks of Aging15:30 – AI and aging iology21:20 – Discovery science and intervention screening24:23 – WormBot and Million Molecule Challenge29:17 – Caloric restriction and combination therapies34:38 – Rapamycin trials in India41:16 – Longevity biomarkers and clinical trials47:34 – Preventative longevity medicine50:30 – Supplements and longevity hype54:29 – Biological clocks and epigenetic testingAbout Matt KerberleinMatt Kaeberlein, Professor at the University of Washington, and Co-Director of the Dog Aging Project. His research focuses on understanding the biological mechanisms of aging and developing interventions to improve healthspan in both humans and companion animals.He has published over 250 scientific papers in aging biology and is a Fellow of the AAAS, AGE, and GSA. Dr. Kaeberlein has received several major awards in gerontology and previously served as Director of the University of Washington Healthy Aging and Longevity Research Institute and the NIH Nathan Shock Center of Excellence in the Basic Biology of Aging.

2. 

   18 Feb 2026

   Episode 10: Blue Zones Blueprint: India-Singapore Aging Breakthroughs | Brian Kennedy

   In this episode, Mr. Prashant Prakash and Prof. Deepak Saini are joined by Prof. Brian Kennedy, and the conversation spans the science and systems shaping healthy longevity today — from second-generation aging clocks, biomarkers, peptides, stem cells, and omics-driven personalization, to what these advances mean for India’s biologically and culturally diverse population. Prof. Kennedy also shares insights from Singapore’s ABIOS biobank (400+ participants), India’s ambition to build 5,000+ profiles, and why collaboration between Bengaluru and Singapore could be critical for the future of longevity science.Beyond biology, the episode unpacks Singapore’s “blue zone–like” success through urban design, green spaces, and active living, and traces Prof. Kennedy’s journey from foundational discoveries in yeast to human health-span trials. The discussion also examines evidence-backed interventions such as spermidine, AKG, Ashwagandha, and Brahmi, alongside emerging questions around NAD+, AI, and aging clocks.Timestamps00:00 – Introduction01:50 – Introduction to Prof. Brian Kennedy02:42 – Singapore as a “Blue Zone”05:00 – Diet and health shifts05:50 – Longevity impact06:10 – Research and trials08:55 – India and aging research11:10 – ABIOS and the BHARAT study13:00 – AI in longevity science17:20 – Biomarkers and omics19:10 – Vitamins, supplements, and interventions22:45 – Spermidine24:25 – Ayurveda28:10 – NAD+, AKG, and indicators31:45 – Aging clocks34:25 – Key biological pathwaysProf. Kennedy is a Director of the Healthy Longevity Translational Research Programme at the Luan School of Medicine, National University of Singapore.He unpacks Singapore’s “blue zone” success through urban design, green spaces, and active living, and the episode traces Prof. Kennedy’s journey from foundational discoveries in yeast to human health-span trials. The discussion also examines interventions such as spermidine, AKG, Ashwagandha, and Brahmi, alongside emerging questions around NAD+, AI, and aging clocks.About Biopeak: Biopeak is a deep science-led longevity organization focused on personalized, precise, predictive, and preventive healthcare. Built for South Asia, our approach blends cutting-edge diagnostics with systems science to craft personalised health plans. Biopeak helps you not just live longer—but live without limits. Biopeak. Decode your path to Limitless Living. Follow Us: Longevity India: https://www.longevity.iisc.ac.in/ Biopeak: https://biopeak.com/ LinkedIn: https://www.linkedin.com/company/longevity-india-iisc/ Instagram: https://www.instagram.com/longevity_iisc/ Spotify: https://open.spotify.com/show/0NXTdG0fBIfmKIHV2vkxbV Disclaimers: The content shared on the Biopeak Live podcast is intended for general educational purposes only and should not be considered as medical advice. We strongly recommend consulting a licensed healthcare professional for any health-related concerns, especially before making any lifestyle, dietary, or medical changes based on the content provided in this podcast. References:https://www.youtube.com/watch?v=5KvXrVmYWlYBiomarkers of aging for the identification and evaluation of longevity interventionsValidation of biomarkers of agingLongevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevityHallmarks of female reproductive aging in physiologic aging mice

3. 

   21 Nov 2025

   Episode 9: Art of Aging Well- Resilience, Hormesis, & Longevity | Dr. Suresh Rattan

   In this episode, Prof. Deepak Saini welcomes Dr.Suresh Rattan, Professor Emeritus, Aarhus University, to share his lifelong journey studying the science of aging and how simple daily choices can shape how well we age. Dr. Rattan blends biology, philosophy, and culture to examine aging not just as a biological process, but as a meaningful aspect of being human.Time stamps00:00 – Introduction00:16 – Introduction to Dr. Suresh Ratan05:34 – Gerontogenes: “Genes for Aging”08:05 – Aging is no longer an unsolved problem09:38 – Why aging is now a major research focus10:34 – How molecular biology revolutionised aging research11:38 – Is there a “formula for immortality”?12:35 – Rapamycin: a hormetic drug?19:30 – The hormetic way of health20:20 – Principles of a hormetic lifestyle26:57 – Ayurveda’s role in aging research31:02 – The knowledge gap in understanding aging33:47 – Aging clocks36:07 – Hormetins everyone should consider41:50 – Final thoughts on immortalityDr. Suresh Rattan is a distinguished biogerontologist and Professor Emeritus at Aarhus University, Denmark, is renowned for his pioneering research in the biology of aging and healthy longevity. Over a career spanning more than four decades, Dr. Rattan has led theLaboratory of Cellular Ageing since 1984, and has made notable contributions to understanding cellular mechanisms of ageing, including the concepts of virtual Gerontogenes and hormesis in aging modulation. He is credited as the sole inventor of the anti-aging effects of kinetin and zeatin, now widely used in skincare products, and has published over 300 research articles and 23 books on aging science, while also foundingand serving as Editor-in-Chief of the influential journal Biogerontology.Connect with Dr. Suresh Rattan:https://sureshrattan.com/https://www.linkedin.com/in/suresh-rattan-7951804/About Biopeak: Biopeak is a deep science-led longevity organization focused on personalized, precise, predictive, and preventive healthcare. Built for South Asia, our approach blends cutting-edge diagnostics with systems science to craft personalised health plans. Biopeak helps you not just live longer—but live without limits.Biopeak. Decode your path to Limitless Living.Follow Us:Longevity India: https://www.longevity.iisc.ac.in/Biopeak: https://www.biopeak.com/LinkedIn: https://www.linkedin.com/company/longevity-india-iisc/Instagram: https://www.instagram.com/longevity_iisc/Spotify: https://open.spotify.com/show/0NXTdG0fBIfmKIHV2vkxbVDisclaimers:The content shared on the Biopeak Live podcast is intended for general educational purposes only and should not be considered as medical advice. We strongly recommend consulting a licensed healthcare professional for any health-related concerns, especially before making any lifestyle, dietary, or medical changes based on the content provided inthis podcast.References:Holliday R. Aging is no longer an unsolved problem in biology. Ann N Y Acad Sci. 2006May;1067:1-9. doi: 10.1196/annals.1354.002. PMID: 16803964.Hayflick L. Biological aging is no longer an unsolved problem. Ann N Y Acad Sci. 2007Apr;1100:1-13. doi: 10.1196/annals.1395.001. PMID: 17460161.Rattan, S.I.S. Seven knowledge gaps in modern biogerontology. Biogerontology 25, 1–8(2024). https://doi.org/10.1007/s10522-023-10089-0Rattan, Suresh. (2008). Principles and practice of hormetic treatment of aging andage-related diseases. Human & experimental toxicology. 27. 151-4.10.1177/0960327107083409.Rattan, S. (2011). Biological principles of aging and approaches for intervention. In A. Olgun(Ed.), The field of biological aging: past, present and future (pp. 1-15). Transworld ResearchNetwork. http://www.trnres.com/ebook/uploads/olguncontent/T_13256689461%20Olgun.pdfhttps://sureshrattan.com/wp-content/uploads/2015/11/Rattan-NutrHormetin_BioactiveFood2013.pdfhttps://sureshrattan.com/tag/books/

4. 

   3 Oct 2025

   Episode 8: Immune Clocks, Inflammation and Aging

   In this episode, Prof. Deepak Saini welcomes Prof. David Furman to discuss the intricate relationship between the immune system, inflammation, and the biology of aging. The conversation highlights the development of a new aging clock based on immune biomarkers, offering insights into multimorbidity and how environmental and genetic factors together shape the aging process. Special attention is given toexternal environmental stressors—including pollutants, toxins, plastics, andcosmetics—that can penetrate biological barriers and accelerate cellular decline, underscoring the importance of public awareness and policymaking in mitigating these risks.The discussion then turns to innovative diagnostic approaches, with a focus on quantum electro spectroscopy as a promising tool for identifying immune system biomarkers and advancing personalized medicine.Prof. Furman also explores unique research models, such as space flight and microgravity experiments, to better understand cellular aging mechanisms and compare them with other experimentalmodels.Finally, lifestyle considerations are examined, with emphasis on how lessons from hunter-gatherer living—marked by activity and natural resilience—may protect against inflammation and chronic disease far more effectively than sedentary modern lifestyles.Time stamps:00:00 – Introduction01:27 – Introduction to Dr. David Furman02:00 – Relationship between the Immune system, Inflammation and Aging07:05 – Environmental factors, immune profiles & baseline values10:20 – AI, tech, and aging research16:23 – Aging in microgravity24:02 – Inflammation and aging29:15 – Exposomal factors contributing to inflammation35:40 – Diversity in microbiome38:57 – Dr. Furman’s personal practices for longevity43:00 – Wearables and trajectories of health47:16 – Aging clocks48:57 – SupplementsAbout Guest: David Furman, PhD, is an Associate Professor and Director of the AI and Bioinformatics Platform at the Buck Institute for Research on Aging, where his work centers on using advanced technologies to gain insight into how people age and how aging can be improved. He is renowned for his interdisciplinary approach, integrating big data, artificial intelligence, and machine learning to analyze the immune system and uncover its role in aging and related diseases. Dr. Furman’sresearch has led to developments such as an inflammatory-aging clock andcollaborations across diverse fields, all aimed at understanding how life experiences and exposures (the “exposome”) impact the immune system and influence the rate of aging.Connect with Dr. David Furman:Furman lab: https://www.buckinstitute.org/lab/furman-lab/Edifice health: https://edificehealth.com/team/david-furman-phdAbout Biopeak: Biopeak is a deep science-led longevity organization focused on personalized, precise, predictive, and preventive healthcare. Built for South Asia, our approach blends cutting-edge diagnostics with systems science to craft personalised health plans. Biopeak helps you not just live longer—but live without limits. Biopeak. Decode your path to Limitless Living.Follow Us: Longevity India: https://www.longevity.iisc.ac.in/Biopeak: https://www.biopeak.com/LinkedIn: https://www.linkedin.com/company/longevity-india-iisc/Instagram: https://www.instagram.com/longevity_iisc/Spotify: https://open.spotify.com/show/0NXTdG0fBIfmKIHV2vkxbVDisclaimers: The content shared on the Biopeak Live podcast is intended for general educational purposes only and should not be considered as medical advice. We strongly recommend consulting a licensed healthcare professional for any health-related concerns, especially before making any lifestyle, dietary, or medical changes based on the content provided in this podcast.

5. 

   3 Sept 2025

   Episode 7: Living by the Clock: How Time Shapes Your Health | Satchin Panda

   In this episode, we’re joined by Dr. Satchidananda Panda, Professor at the Regulatory Biology Laboratory, Salk Institute, California, to dive into the fascinating science of the circadian rhythm and its powerful impact on our health. We explore the importance of circadian rhythm for the body’s daily functioning and how it works, along with the health risks that come from disrupting it, something common among shift workers, students, and new mothers. Dr. Panda also explains how hormones, light, and food influence our internal clock, and shares practical tips to reset and restore balance when our rhythm gets off track. He emphasizes why aligning with the circadian rhythm is key for lifestyle changes, better health, and long-term longevity. When your circadian rhythm is in sync, it boosts overall health, but when disrupted, it can raise the risk of chronic disease and poor health. Time stamp: 00:00- Introduction 01:41- Introduction to Dr. Satchin Panda 06:09- Fundamental functions of circadian clock 08:45- Circadian Clock gene 11:59- Hormonal regulation of circadian clock 14:55- Technology to measure circadian clock 19:01- Shift worker 26:35- Time restricted eating 31:07- Sleep and food timing 38.35- Effect on pathologies and life incidence 40:58- Night Owl 45:34- Entrepreneurship in the circadian rhythm space 50:24- Rapid fire questions #health, #longevity, #biologicalclock, #circadianrhythm, #stress, #sleep, #metabolism, #aging The Guest : Dr. Satchidananda (Satchin) Panda, is a Professor at the Salk Institute in California, where he conducts groundbreaking research on circadian rhythms and their impact on behaviour, physiology, and metabolism. He has been recognized with prestigious awards, including the Julie Martin Mid-Career Award in Aging Research and the Dana Foundation Award in Brain and Immune System Imaging. Discovered blue-light sensing cells in the retina which influence our circadian clock and related behaviours. His work has highlighted time-restricted feeding and its potential in preventing and reversing metabolic diseases. Connect with Dr. Satchidananda Panda: Panda Lab: https://panda.salk.edu (https://panda.salk.edu) Ontime Health: https://getontimehealth.com Know more: The Circadian Code: https://www.penguinrandomhouse.com/books/592260/the-circadian-code-by-satchin-panda-phd/ About Biopeak : Biopeak is a deep science-led longevity organization focused on personalized, precise, predictive, and preventive healthcare. Built for South Asia, our approach blends cutting-edge diagnostics with systems science to craft personalised health plans. Biopeak helps you not just live longer—but live without limits. Biopeak. Decode your path to Limitless Living. Follow Us: Longevity India: https://www.longevity.iisc.ac.in/podcast (https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqblA2cnFhZjUwNkg3VnRIYm1RbWFfU3c0b0RWd3xBQ3Jtc0tsQkF3QTZZUk1VT3ZpN2ZiTjZFOGNDcjU0NXh5RzNfOW9hS2REbkF6UE95c3dPS0xHblJKMWVxa1g1bVFWTXAyUWJZZnRTYlRaR25wWGVfb3lKNUd2OG1VZ3FKQ2JWSzZuZnJhaXhzUnV2ekNZS2toYw&q=https%3A%2F%2Fwww.longevity.iisc.ac.in%2Fpodcast&v=pixEZBFzX0Q) Biopeak: https://www.biopeak.com/ (https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbVF0RkZHVXdMcEhyRzVMMVNFUUliaGtNYnlmQXxBQ3Jtc0trNlFPTTZ0UHh1YjN0S25EbGhpWHY4Z0VHMmlQSUpWQ2FQSDdselRNVHNRWnJ4RG9XMlNUTG5PcjYyTnJMYnBvdWNKajRrR3o5dW9la01oZEdiMUdHTnFBbnpvZFpXTG1Vd3ZMM29mX3ZmMDMzU0VoSQ&q=https%3A%2F%2Fwww.biopeak.com%2F&v=pixEZBFzX0Q) LinkedIn:   / longevity-india-iisc   (https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqblplaFpVSkN0UnpDbEpTWFRlak96WkhyQm1PQXxBQ3Jtc0tueXhveEpYdlIxY1lyOVFQZGIwX2o2MDNZc2dqTERseVp0blJYVlMyQ0NsdkhvbnBnWE0zaS14dmRJbEl2cDBiZVAxY0tPdGs4V0NOclpPX1Q3RG1JbzgzTGNQZ3lmdTJPSzhuQmYtb3lPZkd2WmZmYw&q=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Flongevity-india-iisc%2F&v=pixEZBFzX0Q) Instagram:   / longevity_iisc   (https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbmRpTWppVWplTDBDeks0YVp1LTVDdEFWYWdHd3xBQ3Jtc0tuYWZ4TC1UdFFlbFJVYVRvbThJR1NaV3dFMXBsRU95MW83SHVqVE9aekFtV1Bja3lMSVhiYjJvSUowRkpwM1cyaEdpcEFWLWMtbGtuT1ZfUVh4RjU3V1pMcVJqY0pNTFROcVVtamd1cjdOR3Z4enpSZw&q=https%3A%2F%2Fwww.instagram.com%2Flongevity_iisc%2F&v=pixEZBFzX0Q) Disclaimers: The content shared on the Biopeak Live podcast is intended for general educational purposes only and should not be considered as medical advice. We strongly recommend consulting a licensed healthcare professional for any health-related concerns, especially before making any lifestyle, dietary, or medical changes based on the content provided in this podcast.

6. 

   8 Aug 2025

   Episode 6: Metabolic Dysfunction Explained | Sue Anne Part-2

   In continuation of our conversation from previous episode with Dr. Sue Anne Toh, Co-Founder and Director of NOVI, we dive deeper into what happens when the drivers of metabolism go off track - leading to metabolic dysfunction. We explore how factors like body composition, insulin resistance, and chronic inflammation contribute to metabolic syndrome, particularly in South Asian populations. Dr. Toh shares insights on how wearable devices can empower individuals to understand their physiology and make meaningful behaviour changes.We also cover practical ways to improve gut health and rapid-fire round tackling common metabolism myths and facts.Time stamps:01:40 - Introduction Sue Anne 03:36 - Drivers of metabolism and metabolic syndrome 06:32 - Indicators of metabolic distress 10:53 - HbA1c marker16:14 - Inflammation on metabolism 24:38 - Inflammation marker threshold27:05 - Skinny fat cannot be eyeball, how to triage – Asian population 31:07 - Metabolic markers-Indian 32:24 - Supplements to delay metabolic distress onset 35:58 - Local nutraceuticals36:57 - Sequencing order of food40:58 - Time restricted eating44:30 - Wearables in managing health 55:04 - Negative gamification of wearable device57:02 - Convergence of health monitoring devices and AI58:47- Metabolic age01:00:00 - Exercise01:05:05 - Supplements for better gut health01:08:22 - Rapid fire- practical questions 01:16:46 - ClosingThe Guest: Dr. Sue Anne Toh is the Co-Founder, CEO and Medical Director of NOVI. She is also Adjunct Associate Professor, Yong Loo Lin School of Medicine, National University of Singapore. Dr. Toh is a specialist in internal medicine, diabetes, endocrinology, and metabolism, with expertise in health systems, value-based healthcare, evidence-based wellness, integrated health services development, delivery, and evaluation.Connect with Dr. Sue Anne Toh: https://novi-health.com/ ( https://novi-health.com/) ,https://www.linkedin.com/in/sue-anne-toh-4225897/ (https://www.linkedin.com/in/sue-anne-toh-4225897/ )References:1.https://clinicaltrials.gov/study/NCT02838693?term=NCT02838693&rank=1 (1.https://clinicaltrials.gov/study/NCT02838693?term=NCT02838693&rank=1)2.Magkos F, Lee MH, Lim M, Cook AR, Chhay V, Loh TP, Chia KS, Baig S, Ang IYH, Tay JYY, Khoo CM, Halter JB, Toh SA. Dynamic assessment of insulin secretion and insulin resistance in Asians with prediabetes. Metabolism. 2022 Mar;128:154957. doi: 10.1016/j.metabol.2021.154957. Epub 2021 Dec 21. PMID: 34942192. (Magkos F, Lee MH, Lim M, Cook AR, Chhay V, Loh TP, Chia KS, Baig S, Ang IYH, Tay JYY, Khoo CM, Halter JB, Toh SA. Dynamic assessment of insulin secretion and insulin resistance in Asians with prediabetes. Metabolism. 2022 Mar;128:154957. doi: 10.1016/j.metabol.2021.154957. Epub 2021 Dec 21. PMID: 34942192.)3.Lee MH, Febriana E, Lim M, Baig S, Halter JB, Magkos F, Toh SA. Asian females without diabetes are protected from obesity-related dysregulation of glucose metabolism compared with males. Obesity (Silver Spring). 2023 Sep;31(9):2304-2314. doi: 10.1002/oby.23833. Epub 2023 Aug 3. PMID: 37534562. (Lee MH, Febriana E, Lim M, Baig S, Halter JB, Magkos F, Toh SA. Asian females without diabetes are protected from obesity-related dysregulation of glucose metabolism compared with males. Obesity (Silver Spring). 2023 Sep;31(9):2304-2314. doi: 10.1002/oby.23833. Epub 2023 Aug 3. PMID: 37534562.)4.Lee MH, Febriana E, Lim M, Baig S, Shen L, Dalakoti M, Chew N, Loh TP, Chan M, Chia KS, Kong AP, Cook AR, Halter JB, Magkos F, Toh SA. Performance of the 1 h oral glucose tolerance test in predicting type 2 diabetes and association with impaired β-cell function in Asians: a national prospective cohort study. Lancet Reg Health West Pac. 2024 Dec 31;54:101278. doi: 10.1016/j.lanwpc.2024.101278. PMID: 39840148; PMCID: PMC11750441 (Lee MH, Febriana E, Lim M, Baig S, Shen L, Dalakoti M, Chew N, Loh TP, Chan M, Chia KS, Kong AP, Cook AR, Halter JB, Magkos F, Toh SA. Performance of the 1 h oral glucose tolerance test in predicting type 2 diabetes and association with impaired β-cell function in Asians: a national prospective cohort study. Lancet Reg Health West Pac. 2024 Dec 31;54:101278. doi: 10.1016/j.lanwpc.2024.101278. PMID: 39840148; PMCID: PMC11750441).About Biopeak: Biopeak is a deep science-led longevity organization focused on personalized, precise, predictive, and preventive healthcare. Built for South Asia, our approach blends cutting-edge diagnostics with systems science to craft personalised health plans. Biopeak helps you not just live longer—but live without limits. Biopeak. Decode your path to Limitless Living.Follow Us: Longevity India: https://www.longevity.iisc.ac.in/ (https://www.longevity.iisc.ac.in/)Biopeak: https://www.biopeak.com/ (https://www.biopeak.com/)LinkedIn: https://www.linkedin.com/company/longevity-india-iisc/ (https://www.linkedin.com/company/longevity-india-iisc/)Instagram: https://www.instagram.com/longevity_iisc/ (https://www.instagram.com/longevity_iisc/)Spotify: https://open.spotify.com/show/0NXTdG0fBIfmKIHV2vkxbV (//open.spotify.com/show/0NXTdG0fBIfmKIHV2vkxbV)

7. 

   21 Jul 2025

   Episode 5 - Drivers of Metabolism | Sue Anne Part-1

   In this episode, we’re joined by Dr. Sue Anne Toh, Co-Founder and Director of NOVI, for an insightful discussion on metabolism. We explore key aspects of metabolism, including the roles of organs, hormones, metabolic rate, and metabolic health. Dr. Toh also highlights the distinct metabolic traits seen in Indian and broader Asian populations, emphasizing the importance of studying and understanding our own population for more effective health strategies.Time stamp:00:00 - Introduction01:39 - Introduction Sue Anne Toh 04:44 - Mitochondria – hub of metabolism 09:16 - Is mitochondria making us age ? Function of mitochondria 13:05 - Different fuel different effect- depend on the whole being 16:25 - Regulatory mechanisms and organs involved in metabolic control20:30 - Signs of metabolic dysfunction 24:47 - Metabolic rate 35:07 - BMI of south Asian Population 37:26 - Skinny fat38:31 - South-east Asians need to work harder to keep metabolically fit45:00 - Summary and closingThe Guest: Dr. Sue Anne Toh is the Co-Founder, CEO and Medical Director of NOVI. She is also Adjunct Associate Professor, Yong Loo Lin School of Medicine, National University of Singapore. Dr. Toh is a specialist in internal medicine, diabetes, endocrinology, and metabolism, with expertise in health systems, value-based healthcare, evidence-based wellness, integrated health services development, delivery, and evaluation.Connect with Dr. Sue Anne Toh: https://www.linkedin.com/in/sue-anne-toh-4225897/ (https://www.linkedin.com/in/sue-anne-toh-4225897/)References: 1.Cypess AM, Lehman S, Williams G, Tal I, Rodman D, Goldfine AB, Kuo FC, Palmer EL, Tseng YH, Doria A, Kolodny GM, Kahn CR. Identification and importance of brown adipose tissue in adult humans. N Engl J Med. 2009 Apr 9;360(15):1509-17. doi: 10.1056/NEJMoa0810780. PMID: 19357406; PMCID: PMC2859951.2.Parvaresh Rizi E, Baig S, Shabeer M, Teo Y, Mok SF, Loh TP, Magkos F, Virtue S, Vidal-Puig A, Tai ES, Khoo CM, Toh SA. Meal rich in carbohydrate, but not protein or fat, reveals adverse immunometabolic responses associated with obesity. Nutr J. 2016 Dec 1;15(1):100. doi: 10.1186/s12937-016-0219-0. PMID: 27903298; PMCID: PMC5131405.3.Baig S, Parvaresh Rizi E, Shabeer M, Chhay V, Mok SF, Loh TP, Magkos F, Vidal-Puig A, Tai ES, Khoo CM, Toh SA. Metabolic gene expression profile in circulating mononuclear cells reflects obesity-associated metabolic inflexibility. Nutr Metab (Lond). 2016 Oct 27;13:74. doi: 10.1186/s12986-016-0135-5. PMID: 27800008; PMCID: PMC5081666.Parvaresh Rizi E, Loh TP, Baig S, Chhay V, Huang S, Caleb Quek J, Tai ES, Toh SA, Khoo CM. A high carbohydrate, but not fat or protein meal attenuates postprandial ghrelin, PYY and GLP-1 responses in Chinese men. PLoS One. 2018 Jan 31;13(1):e0191609. doi: 10.1371/journal.pone.0191609. PMID: 29385178; PMCID: PMC5792004.About Biopeak:Biopeak is a deep science-led longevity organization focused on personalized, precise, predictive, and preventive healthcare. Built for South Asia, our approach blends cutting-edge diagnostics with systems science to craft personalised health plans. Biopeak helps you not just live longer, but live without limits.Biopeak. Decode your path to Limitless Living.Follow Us:Longevity India⁠ (https://www.longevity.iisc.ac.in/podcast) ⁠Biopeak⁠ (https://www.biopeak.com/) ⁠LinkedIn⁠ (https://www.linkedin.com/company/100882463/admin/dashboard/) ⁠Instagram⁠ (https://www.instagram.com/longevity_iisc/) ⁠Spotify⁠ (https://open.spotify.com/show/0NXTdG0fBIfmKIHV2vkxbV) ⁠Apple podcast⁠ (https://podcasts.apple.com/us/podcast/biopeak-live-longevity-india-podcast/id1811522906)Disclaimers:The content shared on the Biopeak Live podcast is intended for general educational purposes only and should not be considered as medical advice. We strongly recommend consulting a licensed healthcare professional for any health-related concerns, especially before making any lifestyle, dietary, or medical changes based on the content provided in this podcast.

8. 

   4 Jun 2025

   Episode 4 - The Longevity Leap & Upcoming Revolution | Rajesh Reddy Part - 3

   Investor Rajesh Reddy explores technology's impact on healthcare, including digital platforms, longevity clinics, and AI-driven care, with host Prashanth Prakash and Prof. Deepak Saini in an interview.

9. 

   15 May 2025

   Episode 3 – Central Dogma of Longevity | Rajesh Reddy Part 2

   Rajesh Reddy discusses genome-phenome interactions and their impact on health and longevity with Prashanth Prakash and Deepak Saini, exploring genetic predispositions and personalized treatments relevant to Indian populations in this interview.

10. 

    30 Apr 2025

    Episode 2 – Unlocking Longevity Perspectives | Rajesh Reddy Part 1

    Tech entrepreneur Rajesh Reddy discusses evolving perceptions of healthy aging in India and globally through culture, spirituality, and vanity with Prashanth Prakash and Deepak Saini in this interview.

11. 

    14 Apr 2025

    Episode 1: Hallmarks of Aging

    Host Prashanth Prakash and co-host Deepak Saini interview Nobel laureate Dr. Venki Ramakrishnan, exploring the hallmarks of aging, breakthroughs in interventions, and key focus areas to address aging challenges.

Podcast Authority Score: 12 / 100

A composite of feed quality, social presence, YouTube performance and engagement. Read the methodology.

Quality

6

Social presence

94

YouTube

0

Engagement

0