Welcome to Cardio Insights by Roche, a podcast dedicated to exploring the digital transformation of cardiovascular and emergency medicine. Join us as we feature thought leaders from top institutions worldwide, delving into the power of clinical algorithms and decision-support tools.
We examine their impact on clinical practice, patient outcomes, and health system challenges like implementation and regulation. Learn from leading experts in the field with Cardio Insights, offering unique insights and perspectives for cardiologists, emergency medicine professionals and healthcare leaders.
Episode 12: Understanding current industry trends, challenges, and opportunities, with Dr. Matthew S. Prime
How might we unleash the full potential of digital solutions in healthcare?
In this episode, featuring Dr. Matthew Prime from Roche Diagnostics, we dive into the current challenges that hospitals and health systems face globally, and how innovation might be driven collaboratively between public and private actors to move digital solutions forward.
Based on his experience as a clinician and business leader, Dr. Prime shares his views on key success criteria to deliver impactful digital solutions for health systems, the constraints that need to be acknowledged, and some of the greatest breakthroughs he has witnessed through working with leading hospitals and institutions across the globe.
Dr. Matthew S. Prime is an Orthopedic Surgeon, Entrepreneur, and International Business Leader for Clinical Decision Solutions and Algorithms at Roche Diagnostics. His work focuses on developing, validating, and commercializing clinical decision-support tools and algorithms deployed in hospitals and medical institutions worldwide.
25 Apr 2025
Episode 11: Regulating innovation through policy and legislation, with Dr. Afua Van Haasteren
What role do policy and legislation play in managing access to digital solutions within health systems?
In this episode, featuring Afua Van Haasteren from Roche Diagnostics, we look at some of the approaches that policymakers, legislators, and international organizations follow to influence the use of healthcare solutions, including those of a digital nature.
Dr. Van Haasteren touches on the role of reimbursement and alternative funding mechanisms as drivers of digital innovation, while emphasizing the importance of data governance mechanisms and the need for value assessment methods that capture the complexity of the most recent technologies.
Dr. Afua Van Haasteren is a Director of Health Policy and External Affairs at Roche Diagnostics, with a background in digital health spanning philanthropy, academia, and the industry. She leads data and digital policy efforts, collaborating with external stakeholders to advocate for effective artificial intelligence, data governance, legislation, and policies that enhance patient access to digital health solutions.
16 Apr 2025
Episode 10: Lifting the veil on market access and its modalities, with Dr. Paul Neveux
What is market access and how does it contribute to evidence generation and clinical adoption of digital solutions?
In this episode featuring Dr. Paul Neveux, Access Evidence Leader at Roche Diagnostics, we explore the intricacies of market access regarding digital solutions and its role in demonstrating value to health systems, ultimately driving clinical adoption and patient access.
Dr. Neveux shares the types of studies that are part of this discipline, the stakeholders it serves within healthcare systems, and the subtleties that apply in particular to solutions that are digital in nature.
Dr. Paul Neveux is an Access Evidence Leader at Roche Diagnostics, with a background in public health, management, and health policy science, spanning academia, and the industry. His work focuses on the development of payer-relevant deliverables such as health economic models, to support reimbursement requests and price negotiations.
11 Apr 2025
Episode 9: Leading development and implementation through close collaboration, with Sara Zimbardo
How can digital solutions be fit for purpose for healthcare professionals, while compatible with local infrastructures and clinical practices?
In this episode, featuring Sara Zimbardo from Roche Diagnostics, we tackle the complexities that come with developing and deploying digital solutions in healthcare, where clinical workflows, IT infrastructures, and guidelines can vary greatly across geographies.
Drawing from her work as a user experience researcher and engineer, Ms. Zimbardo shares her learnings on the key steps to follow when designing and implementing such solutions with the end user in mind, and navigating the diversity of systems and cultures across healthcare institutions.
Sara Zimbardo, MSc. is a Senior User Experience Designer and Researcher at Roche Diagnostics, with a background in design and engineering. She focuses on integrating user perspectives into product development to create solutions tailored to users' and customers' needs. She has a strong experience and interest in healthcare product design, exemplified by her work on smart systems for centralized laboratory monitoring and clinical algorithms.
4 Apr 2025
Episode 8: Exploring solutions to manage acute coronary syndrome, with Prof. Evangelos Giannitsis
Can we streamline the diagnosis and management of acute coronary syndrome in the emergency department?
In this episode, we hear Prof. Evangelos Giannitsis from the University of Heidelberg, on what characterizes acute coronary syndrome, the complexities that come with its recognition and treatment, and how clinical decision support tools are moving clinical practice forward.
In an era where emergency settings are overcrowded and healthcare resources are limited, Prof. Giannitsis shares his perspective on the aspects of digital solutions that can advance patient triage, risk assessment, resource allocation, and adherence to care protocols.
Dr. Evangelos Giannitsis is a Senior Physician in the Cardiology, Angiology, and Pneumology Clinic, and Assistant Professor of Medicine at the University of Heidelberg. He is also the Research Group Leader for the Cardiac Biomarker Group, leading the Chest Pain Unit initiative of the German Society of Cardiology, and presiding as the Chair of the certification committee for Chest Pain Units. He has co-authored more than 600 publications that focus on cardiac biomarkers and their use in diagnosing coronary syndromes.
28 Mar 2025
Episode 7: Advancing coronary artery disease treatment, with Prof. Hans-Peter Brunner-La Rocca
How might we address the complexities of diagnosing and managing coronary artery disease through digital solutions?
In this episode, featuring Prof. Hans-Peter Brunner-La Rocca from Maastricht University Medical Center+, we talk about current approaches to diagnosing coronary artery disease, involving non-invasive and invasive testing methods, and their current limitations.
Prof. Brunner-La Rocca covers the evolution of clinical practices for treating this condition, highlighting how digital solutions can enhance disease detection, guide clinical interventions, and improve risk prediction accuracy through their ability to analyze patient data holistically.
Dr. Hans-Peter Brunner-La Rocca is the Director of the Heart Failure Clinic and Vice Chairman of the Department of Cardiology at Maastricht University Medical Center+. His work focuses on the use of biomarkers and digital health to individualize therapy and management of chronic heart failure, through which he has co-authored more than 400 peer-reviewed publications. He also led several clinical trials, among which the TIME-CHF study, which is one of the key biomarker guidance trials in heart failure.
21 Mar 2025
Episode 6: Bridging cognitive psychology and clinical decision-making, with Prof. Wolf Hautz
Is there a way to tackle medical errors by incorporating cognitive psychology into clinical decision-support tools?
In this episode, featuring Prof. Wolf Hautz from Bern University Hospital, we discuss the challenge posed by misdiagnoses in cardiovascular and emergency medicine, and the complexities of clinical decisions made in these specialties.
According to Prof. Hautz, digital solutions need to go beyond applications specific to an individual condition and provide more agnostic guidance to have an impact in the field. His thesis encourages the convergence of cognitive psychology and digital innovation, as a key to developing future solutions.
Dr. Wolf Hautz is Associate Professor and Head of Emergency Medicine at Bern University Hospital, with a background in anaesthesiology and medical education. Throughout his career, he has co-authored more than 100 peer-reviewed publications in areas including diagnostic decision-making in clinical medicine, digital decision-making tools in emergency care, and evidence-based medical education.
14 Mar 2025
Episode 5: Addressing healthcare overcrowding and resource management, with Prof. Martin Than
Can digital solutions help reduce overutilization of care and streamline resource management?
In this episode, featuring Prof. Martin Than from the University of Otago, we talk about current challenges related to healthcare utilization and overcrowding in emergency departments, as well as the solutions available to tackle them.
Prof. Than offers his stance on some of the root causes and provides a framework to drive innovation in clinical practice through digital solutions, emphasizing the need for integration, efficiency in clinical decision-making, and automation. Dr. Martin Than is an Emergency Medicine Specialist, Director of Emergency Medicine Research at Christchurch Hospital, and Honorary Professor of Medicine at the University of Otago. His work is centered on quality improvement initiatives for the emergency department, focusing on cardiac biomarkers. He notably led the ASPECT study in Asia-Pacific and the clinical trial of a 2-hour diagnostic protocol for cardiac chest pain in the emergency department.
7 Mar 2025
Episode 4: Building evidence to foster trust and adoption, with Prof. Richard Body
What can we do to evaluate digital solutions in a way that builds trust and confidence toward physicians and patients?
In this episode, featuring Prof. Richard Body from Manchester University NHS Foundation Trust, we explore the methods to evaluate the impact of digital solutions on patient outcomes and clinical care, as well as the challenges that these evaluations pose for the development of such solutions.
Drawing from his experience and willingness to go beyond observational studies, Prof. Body shares the framework that guides his approach to evidence generation, explaining the role that real-world data plays in it, and how we might reach new standards in terms of validation and adoption of such solutions in the future.
Dr. Richard Body is an Honorary Consultant in Emergency Medicine, Group Director of Research and Innovation, and Professor of Emergency Medicine at Manchester University NHS Foundation Trust. His work focuses on acute coronary syndrome, diagnostics, clinical epidemiology, biomarkers, and the philosophy of emergency medicine, with more than 200 peer-reviewed publications published so far.
25 Feb 2025
Episode 3: Managing the complexity of clinical adoption, with Prof. Lori B. Daniels and Prof. Cynthia Papendick
How to reconcile digital innovation with clinical reality in cardiology and emergency medicine?
In this episode, featuring Prof. Lori B. Daniels from the University of California in San Diego, and Prof. Cynthia Papendick from the University of Adelaide Medical School, we review the breakthroughs that changed their clinical practice over the years, and what we can learn from their path to implementation and adoption, to foster the emergence of new digital solutions.
From the impact of risk scores, triage algorithms, and high-sensitivity biomarker assays, Prof. Daniels and Prof. Papendick discuss their respective successes and challenges, sharing as well their views on the potential of digital solutions, and the areas where these might address the greatest needs.
Dr. Lori B. Daniels is a Cardiologist, Director of the Cardiovascular Intensive Care Unit, and Professor of Cardiovascular Medicine and Epidemiology at the University of California in San Diego. She has co-authored more than 200 publications in her field, where she focuses on the use of biomarkers to assess cardiovascular risk in a variety of populations.
Dr. Cynthia Papendick is an Emergency Physician at the Royal Adelaide Hospital, and Associate Professor at the University of Adelaide Medical School, focusing her work on improving outcomes and resource utilization for patients presenting to the emergency department with chest pain, particularly those with suspected acute coronary syndrome.
25 Feb 2025
Episode 2: Moving toward smarter clinical decision support, with Prof. Christopher Baugh
What can we expect from future clinical decision-support tools in cardiology and emergency medicine?
In this episode, featuring Prof. Christopher Baugh from Harvard Medical School, we analyze the current state of clinical decision-support solutions in cardiology and emergency medicine. Taking a forward-looking approach, we try to understand what future developments might bring, as technology, medical practice, and health systems progress in their digitalization journey.
According to Prof. Baugh, it is time to move away from purely safety-focused applications acting as alarms and head toward solutions offering a more nuanced basis for decision-making, taking into account each patient's broader risk profile, and reinforcing trust around the use of such solutions.
Dr. Christopher Baugh is Associate Professor in Emergency Medicine at Harvard Medical School, having recently completed a 5-year term as the Vice Chair of Clinical Affairs for the Department of Emergency Medicine at Brigham and Women’s Hospital, where he trained in Emergency Medicine. Throughout his career, he has co-authored over 120 publications on topics related to cardiology, emergency medicine, and oncology, but also in healthcare finance, policy, and clinical operations.
25 Feb 2025
Episode 1: Putting back the patient-physician relationship at the center, with Prof. C. Michael Gibson
What will the future of cardiology and emergency medicine look like, in the era of digital health and artificial intelligence?
In this episode, featuring Prof. C. Michael Gibson from Harvard Medical School, we look at some of the latest technological achievements, and what it will take for health systems to realize their true potential at scale.
This comes with its own set of challenges, related to implementation, adoption, and culture, where a shift in healthcare needs to operate globally.
However, it also nurtures a vision where patients and physicians are placed back at the heart of the matter, fostering trust, communication, and care delivery that is more personalized than ever before.
Dr. C. Michael Gibson is Professor of Medicine at Harvard Medical School, Chief Executive Officer of the non-profit Baim Institute for Clinical Research and the Academic Research Organization PERFUSE, serving as well as Interventional Cardiologist at Beth Israel Deaconess Medical Center. As the inventor of several coronary blood flow measures widely used today in clinical practice, he has led numerous large-scale clinical trials, and his research has been published in more than 700 peer-reviewed publications.
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