Cell Your Idea

About Cell Your Idea

Welcome to Cell Your Idea, the podcast where science meets innovation! We have a passion for exploring the fascinating world of biotechnology and cutting-edge scientific advancements. Our mission is to bridge the gap between laboratory breakthroughs and real-world applications by sharing insightful conversations with experts in the fields of chemistry, biology, and related disciplines. We bring you stories of scientists, researchers, entrepreneurs, and professionals who are pushing the boundaries of knowledge and turning their innovative ideas into reality.

Publisher

Laura and Yana

Category

science

Language

en

Explicit

No

First episode

12 Dec 2023

Latest episode

12 Nov 2024

Latest episodes

4 episodes in the feed.

1. 

   12 Nov 2024

   Heart Innovations: Dr Hofbauer on the Science of Cardioids

   In this episode, we’re joined by Pablo Hofbauer, co-founder of HeartBeat.bio and a leading innovator in self-organizing cardiac organoids, known as cardioids. Pablo shares his journey into biotechnology and explores how cardioids are transforming cardiac drug discovery. We discuss their applications in studying genetic mutations, the significant advantages they offer over traditional 2D models, and their potential to inform future therapies. Pablo also provides insights into the complex process of commercializing scientific research, covering topics from patent strategies to funding challenges. Additionally, he highlights the impact of AI and robotics in enhancing research at HeartBeat.bio. This episode offers an exciting insight into heart health and the evolving landscape of biotech innovation. Timestamps 00:00:49 Introduction to Pablo 00:02:45 What are cardioids? 00:03:59 The Role of Personalised Medicine 00:05:14 Mutations Studies using CRISPR Genetic Engineering 00:08:03 Traditional 2D models vs 3D models of the Heart Chamber 00:13:04 Cell therapy: Pig Heart Transplanted 00:15:06 Future Potential Therapies 00:17:52 Challenges in Commercialisation of Research 00:19:10 Intellectual Property - Patents 00:20:20 Securing funding - Scientific Pitching 00:21:55 Company Partnerships - Robotics 00:23:32 Hitting Milestones 00:26:03 Artificial Intelligence and Machine Learning 00:27:35 Advice for Aspiring Scientists 00:28:38 Fun Fact

2. 

   18 Oct 2024

   Human Metabolism in Bitesize

   This episode explores the topic of metabolism! We discuss biochemical processes, common myths surrounding metabolism and recent scientific findings. The conversation also touches on the rise of drugs like “Ozempic”, initially developed for diabetes but now used for weight loss. We also explain the science behind fasting and its impact on cellular health and longevity. This should be of interest to those curious about novel approaches and technology in the field of metabolism. Timestamp 00:00:15 Introduction to Metabolism 00:02:45 Debunking Common Myths 00:08:53 Weight Loss Drugs 00:12:37 Fasting and Cellular Biology 00:20:46 Conclusion of Discussion 00:21:38 Fun Fact References - Review with a summary table of all rapamycin clinical trials up to date (Konopka et al., 2023). - Caloric Restriction and Aging: Studies in Mice and Monkeys (Anderson et al., 2009). - Cellular mechanisms of Fasting (Mihaylova et al., 2018). - Fasting enhances stem cell function (Imada et al., 2024) - Periodic diet mimics fasting and promotes multi-system regeneration (Brandhorst et al., 2015)

3. 

   1 Feb 2024

   Sleep Science with Prof Jason Rihel

   Our first guest is Prof Jason Rihel, joins us as we discuss sleep. We start off with circadian rhythms, highlighting seasonal affective disorder (winter depression), then continue into understanding the science of sleep, touching on modulation by substances like alcohol, caffeine and cannabis, and then we focus on sleep disorders and diseases related to sleep such as insomnia and Alzheimer’s disease, respectively! Timestamps: 00:00:00 Introduction to Prof Jason Rihel’s Academic Background 00:04:15 Circadian rhythms in zebrafish vs humans 00:05:28 Blind Cavefish, do they have circadian clocks? 00:10:15 Seasonal affective disorder - how light affects humans 00:13:20 Breaking down the sleep stages 00:17:20 What happens to you when you lose sleep? 00:18:58 Alcohol and Caffeine on Sleep 00:22:00 CBD and THC on Sleep 00:26:54 Insomnia 00:29:43 Melatonin 00:34:24 Sleep and Neurodegenerative Diseases 00:40:20 Influence of genetics on Sleep 00:43:35 Genetic Enigma - Superhumans? 00:45:13 Naps 00:46:56 Sleep Hygiene 00:52:06 Fun fact Elephant seal diving research paper: Jessica M. Kendall-Bar et al. , Brain activity of diving seals reveals short sleep cycles at depth. Science 380,260-265(2023). DOI:10.1126/science.adf0566 (https://doi.org/10.1126/science.adf0566)

4. 

   12 Dec 2023

   Meet the Minds Behind Cell Your Idea

   In our debut episode, we kick off our podcast journey with a chat about our academic escapades and how they led us to create Cell Your Idea. We discuss our journey into science and research on neurodegenerative disorders. We reveal what it's like to build a startup that tackles Parkinson's diagnostics as a student in London, including all the challenges and the importance of translating scientific findings into real-world applications. We draw on our student experiences to set the stage for exciting biotech tales to come! Timestamps: (00:00:00) Introduction (00:00:59) UCL and neuroscience (00:03:34) Alzheimer's Disease research (00:16:00) Entrepreneurship experience (00:28:38) Career paths from biosciences (00:40:17) Reflections on academia

Reach and audience

Public platform figures. Ratings count people who left a rating, not total listeners.

Apple Podcasts (US)

5.0 / 5

1 ratings

Spotify

5.0 / 5

19 ratings

Contact Cell Your Idea

Guest appearances

Books guests

Based on episode analysis; this does not confirm that the show is currently accepting guests.