CellOut

About CellOut

Derek DeVries and Ford Fishman tackle the latest issue of a high-impact open access journal: PLoS Biology, from crash courses in bacterial biofilms to high-stakes detours through the Jargon Jungle. Whether you are a neuroscience novice who could use a monthly dose of biology, a curious biology enthusiast looking for a starting point to dive into research yourself, or a scientist in the making who wants a hands-free source of inspiration for your next discovery, come check out our monthly podcast CellOut. Cover Art: C. DeVries (2022)

Publisher

Derek DeVries & Ford Fishman

Category

science

Language

en

Explicit

No

First episode

14 Mar 2022

Latest episode

4 Apr 2023

Latest episodes

11 episodes in the feed.

1. 

   4 Apr 2023

   Lions, Tigers, and Brains

   Wanna learn about our brain's response to electrical stimulation, filamentous fungi, or carnivore attacks? Well, we are BACK with our new-ish, shortened format for Episode 11 of the monthly podcast CellOut. Listen to your favorite pair of biology nerds, Derek DeVries and Ford Fishman, summarize and discuss a sample of articles from the January 2023 issue of PLoS biology. Issue Link: https://journals.plos.org/plosbiology/issue?id=10.1371/issue.pbio.v21.i01 Keywords: biology, life science, open access, scientific journals, science, PLoS, neuroscience, brains, carnivores, poem SHOW NOTES Podcast Art - Credit Caroline DeVries Episode Art - PLoS Biology January 2023 Cover: credit Mazal Cohen-Gulkar and Ruth Ashery-Padan Cutting Edge (1:34) Krause MR, Vieira PG, Pack CC (2023) Transcranial electrical stimulation: How can a simple conductor orchestrate complex brain activity? PLoS Biol 21(1): e3001973. https://doi.org/10.1371/journal.pbio.3001973 Cell Culture (12:03) Author Brandon Sanderson Poem Paper: Chevalier L, Pinar M, Le Borgne R, Durieu C, Peñalva MA, Boudaoud A, et al. (2023) Cell wall dynamics stabilize tip growth in a filamentous fungus. PLoS Biol 21(1): e3001981. https://doi.org/10.1371/journal.pbio.3001981 Journal Club (20:45) Bombieri G, Penteriani V, Almasieh K, Ambarlı H, Ashrafzadeh MR, Das CS, et al. (2023) A worldwide perspective on large carnivore attacks on humans. PLoS Biol 21(1): e3001946. https://doi.org/10.1371/journal.pbio.3001946

2. 

   13 Feb 2023

   Pipes Gone Batty

   Wanna learn about bat larynxes, tiny piscine predators, or competitive corn? Well, we are BACK with our new-ish, shortened format for Episode 10 of the monthly podcast CellOut. Listen to your favorite pair of biology nerds, Derek DeVries and Ford Fishman, summarize and discuss a sample of articles from the November 2022 issue of PLoS biology. Issue Link: https://journals.plos.org/plosbiology/issue?id=10.1371/issue.pbio.v20.i11 Keywords: biology, life science, open access, scientific journals, science, PLoS, viruses, fish, agriculture, bats SHOW NOTES Podcast Art - Credit Caroline DeVries Episode Cover Art - November 2022 PLoS Biology Cover. Image Credit: Erick Bermúdez-Méndez Bite-Sized Discoveries (0:59) Bermúdez-Méndez E, Bronsvoort KF, Zwart MP, van de Water S, Cárdenas-Rey I, Vloet RPM, et al. (2022) Incomplete bunyavirus particles can cooperatively support virus infection and spread. PLoS Biol 20(11): e3001870. https://doi.org/10.1371/journal.pbio.3001870 Dudley SA (2022) Discovering cooperative traits in crop plants. PLoS Biol 20(11): e3001892. https://doi.org/10.1371/journal.pbio.3001892 Mihalitsis M, Morais RA, Bellwood DR (2022) Small predators dominate fish predation in coral reef communities. PLoS Biol 20(11): e3001898. https://doi.org/10.1371/journal.pbio.3001898 Jargon Jungle (12:14) Thanks again to Chris Clayton (OUR NEW JARGON JUNGLE CHAMPION)! Journal Club (18:17) Håkansson J, Mikkelsen C, Jakobsen L, Elemans CPH (2022) Bats expand their vocal range by recruiting different laryngeal structures for echolocation and social communication. PLoS Biol 20(11): e3001881. https://doi.org/10.1371/journal.pbio.3001881

3. 

   14 Dec 2022

   Minute Microgreens and Biofilm Blueprints

   We are BACK with a new, shortened format for Episode 9 of the monthly podcast CellOut. Listen to your favorite pair of biology nerds, Derek DeVries and Ford Fishman, summarize and discuss a sample of articles from the October 2022 issue of PLoS biology. Issue Link: https://journals.plos.org/plosbiology/issue?id=10.1371/issue.pbio.v20.i10 Keywords: biology, life science, open access, scientific journals, science, PLoS, climate change, woodpeckers, neuroscience, bacteria, leaves SHOW NOTES Podcast Art - Credit Caroline DeVries Episode Cover Art - October 2022 PLoS Biology Cover. Image Credit: Joanna Clarke Cutting Edge (1:09) Greene CH, Scott-Buechler CM (2022) Algal solutions: Transforming marine aquaculture from the bottom up for a sustainable future. PLoS Biol 20(10): e3001824. https://doi.org/10.1371/journal.pbio.3001824 Cell Culture (8:59) Based on the move Twilight (2008) Journal Club (21:19) Jeckel H, Díaz-Pascual F, Skinner DJ, Song B, Jiménez-Siebert E, Strenger K, et al. (2022) Shared biophysical mechanisms determine early biofilm architecture development across different bacterial species. PLoS Biol 20(10): e3001846. https://doi.org/10.1371/journal.pbio.3001846

4. 

   8 Nov 2022

   Learn to Use your Head

   After a brief hiatus, we are BACK with Episode 8 of the monthly podcast CellOut, where your favorite pair of biology nerds, Derek DeVries and Ford Fishman, summarize and discuss a sample of articles from the August and September 2022 issues of PLoS biology. Issue Link: https://journals.plos.org/plosbiology/issue?id=10.1371/issue.pbio.v20.i09 Keywords: biology, life science, open access, scientific journals, science, PLoS, climate change, woodpeckers, neuroscience, bacteria, leaves SHOW NOTES Podcast Art - Credit Caroline DeVries Episode Cover Art - September 2022 PLoS Biology Cover. Image Credit: mjeedelbr, Flickr Cutting Edge (1:36) São Pedro VdA, Trierveiler-Pereira L, Baltazar JM (2022) Adapt conservation biology teaching to address eco-anxiety in students. PLoS Biol 20(9): e3001774. https://doi.org/10.1371/journal.pbio.3001774 Jargon Jungle (8:25) Dueling hosts, guest to return next month! Journal Club (22:32) Schuppe ER, Cantin L, Chakraborty M, Biegler MT, Jarvis ER, Chen C-C, et al. (2022) Forebrain nuclei linked to woodpecker territorial drum displays mirror those that enable vocal learning in songbirds. PLoS Biol 20(9): e3001751. https://doi.org/10.1371/journal.pbio.3001751 Cell Culture (42:15) Disco Elysium: https://discoelysium.com/ Bite-Size Discoveries (47:40) VanWallendael A, Benucci GMN, da Costa PB, Fraser L, Sreedasyam A, Fritschi F, et al. (2022) Host genotype controls ecological change in the leaf fungal microbiome. PLoS Biol 20(8): e3001681. https://doi.org/10.1371/journal.pbio.3001681 Linh NM, Scarpella E (2022) Leaf vein patterning is regulated by the aperture of plasmodesmata intercellular channels. PLoS Biol 20(9): e3001781. https://doi.org/10.1371/journal.pbio.3001781 Moutinho AF, Eyre-Walker A, Dutheil JY (2022) Strong evidence for the adaptive walk model of gene evolution in Drosophila and Arabidopsis. PLoS Biol 20(9): e3001775. https://doi.org/10.1371/journal.pbio.3001775 Zhu Y, Chew KY, Wu M, Karawita AC, McCallum G, Steele LE, et al. (2022) Ancestral SARS-CoV-2, but not Omicron, replicates less efficiently in primary pediatric nasal epithelial cells. PLoS Biol 20(8): e3001728. https://doi.org/10.1371/journal.pbio.3001728

5. 

   20 Sept 2022

   Views of a Nation and Regeneration

   Episode 7 of the monthly podcast CellOut, where your favorite pair of biology nerds, Derek DeVries and Ford Fishman, summarize and discuss a sample of articles from the July 2022 issue of PLoS biology. Issue Link: https://journals.plos.org/plosbiology/issue?id=10.1371/issue.pbio.v20.i07 Keywords: biology, life science, open access, scientific journals, science, PLoS, climate change, stem cells, planarians, neuroscience, genetics SHOW NOTES Podcast Art - Credit Caroline DeVries Episode Cover Art - July 2022 PLoS Biology Cover. Image Credit: Quentin Geissmann Cutting Edge (1:31) Sparkman, G., Geiger, N. & Weber, E.U. Americans experience a false social reality by underestimating popular climate policy support by nearly half. Nat Commun 13, 4779 (2022). https://doi.org/10.1038/s41467-022-32412-y Jargon Jungle (8:53) Thanks to Chris for trying to come on the show! We'll bring you back soon! Journal Club (11:18) Issigonis M, Redkar AB, Rozario T, Khan UW, Mejia-Sanchez R, Lapan SW, et al. (2022) A Krüppel-like factor is required for development and regeneration of germline and yolk cells from somatic stem cells in planarians. PLoS Biol 20(7): e3001472. https://doi.org/10.1371/journal.pbio.3001472 Cell Culture (28:48) Sea of Tranquility by Emily St. John Mandel Bite-Size Discoveries (34:12) Jay P, Tezenas E, Véber A, Giraud T (2022) Sheltering of deleterious mutations explains the stepwise extension of recombination suppression on sex chromosomes and other supergenes. PLoS Biol 20(7): e3001698. https://doi.org/10.1371/journal.pbio.3001698 Stone BT, Lin J-Y, Mahmood A, Sanford AJ, Katz DB (2022) LiCl-induced sickness modulates rat gustatory cortical responses. PLoS Biol 20(7): e3001537. https://doi.org/10.1371/journal.pbio.3001537 Bai F, Meyer AS, Martin AE (2022) Neural dynamics differentially encode phrases and sentences during spoken language comprehension. PLoS Biol 20(7): e3001713. https://doi.org/10.1371/journal.pbio.3001713 Baumgartner ME, Mastrogiannopoulos A, Kucinski I, Langton PF, Piddini E (2022) The Gr64 cluster of gustatory receptors promotes survival and proteostasis of epithelial cells in Drosophila. PLoS Biol 20(7): e3001710. https://doi.org/10.1371/journal.pbio.3001710

6. 

   2 Aug 2022

   Jargon Strikes Again

   Episode 6 of the monthly podcast CellOut, where your favorite pair of biology nerds, Derek DeVries and Ford Fishman, summarize and discuss a sample of articles from the June 2022 issue of PLoS biology. Issue Link: https://journals.plos.org/plosbiology/issue?id=10.1371/issue.pbio.v20.i06 Keywords: biology, life science, open access, scientific journals, science, PLoS, viruses, bacteria, fish, embryo, neuroscience, jargon, SHOW NOTES Podcast Art - Credit Caroline DeVries Episode Cover Art - June 2022 PLoS Biology Cover. Image Credit: Erina He, NIH Medical Arts Cutting Edge (2:59) Torri A, Jaeger J, Pradeu T, Saleh M-C (2022) The origin of RNA interference: Adaptive or neutral evolution? PLoS Biol 20(6): e3001715. https://doi.org/10.1371/journal.pbio.3001715 Jargon Jungle (12:25) Thanks to Turner for coming on the show! Reach out to us on twitter or tweet the pokemon that best captures you to #JargonJungle to be considered as our next guest. Journal Club (20:53) Zarrella TM, Khare A (2022) Systematic identification of molecular mediators of interspecies sensing in a community of two frequently coinfecting bacterial pathogens. PLoS Biol 20(6): e3001679. https://doi.org/10.1371/journal.pbio.3001679 Cell Culture (36:12) Dark - https://www.imdb.com/title/tt5753856/ Bite-Size Discoveries (43:22) Langlois J, Guilhaumon F, Baletaud F, Casajus N, De Almeida Braga C, Fleuré V, et al. (2022) The aesthetic value of reef fishes is globally mismatched to their conservation priorities. PLoS Biol 20(6): e3001640. https://doi.org/10.1371/journal.pbio.3001640 Yang Y, Shi L, Fu X, Ma G, Yang Z, Li Y, et al. (2022) Metabolic and epigenetic dysfunctions underlie the arrest of in vitro fertilized human embryos in a senescent-like state. PLoS Biol 20(6): e3001682. https://doi.org/10.1371/journal.pbio.3001682 Khan M, Hartmann AH, O’Donnell MP, Piccione M, Pandey A, Chao P-H, et al. (2022) Context-dependent reversal of odorant preference is driven by inversion of the response in a single sensory neuron type. PLoS Biol 20(6): e3001677. https://doi.org/10.1371/journal.pbio.3001677 Bentley MA, Yates CA, Hein J, Preston GM, Foster KR (2022) Pleiotropic constraints promote the evolution of cooperation in cellular groups. PLoS Biol 20(6): e3001626. https://doi.org/10.1371/journal.pbio.3001626

7. 

   5 Jul 2022

   Stone Cold Secrets

   Episode 5 of the monthly podcast CellOut, where your favorite pair of biology nerds, Derek DeVries and Ford Fishman, summarize and discuss a sample of articles from the May 2022 issue of PLoS biology. Issue Link: https://journals.plos.org/plosbiology/issue?id=10.1371/issue.pbio.v20.i05 Keywords: biology, life science, open access, scientific journals, science, PLoS, pandemic, coral, climate change, paleobiology, neuroscience SHOW NOTES Podcast Art - Credit Caroline DeVries Episode Cover Art - May 2022 PLoS Biology Cover. Image Credit: Dr Charlotte G Kenchington Cutting Edge (1:33) Rice BL, Lessler J, McKee C, Metcalf CJE (2022) Why do some coronaviruses become pandemic threats when others do not? PLoS Biol 20(5): e3001652. https://doi.org/10.1371/journal.pbio.3001652 Jargon Jungle (9:05) Thanks to Jess for coming on the show! Reach out to us on twitter or tweet your favorite combination to #JargonJungle to be considered as our next guest. Journal Club (20:07) Portilho-Ramos RdC, Titschack J, Wienberg C, Siccha Rojas MG, Yokoyama Y, Hebbeln D (2022) Major environmental drivers determining life and death of cold-water corals through time. PLoS Biol 20(5): e3001628. https://doi.org/10.1371/journal.pbio.3001628 Cell Culture (44:17) Arrival - Villeneuve, Denis. Arrival. Paramount Pictures, 2016. Derek's song uses the tune and chords from "I'm with you" by Vance Joy, it is a sad parody and not at all original. Bite-Size Discoveries (42:21) Eden R, Manica A, Mitchell EG (2022) Metacommunity analyses show an increase in ecological specialisation throughout the Ediacaran period. PLoS Biol 20(5): e3001289. https://doi.org/10.1371/journal.pbio.3001289 Shafik SH, Richards SN, Corry B, Martin RE (2022) Mechanistic basis for multidrug resistance and collateral drug sensitivity conferred to the malaria parasite by polymorphisms in PfMDR1 and PfCRT. PLoS Biol 20(5): e3001616. https://doi.org/10.1371/journal.pbio.3001616 Petre B, Kragel P, Atlas LY, Geuter S, Jepma M, Koban L, et al. (2022) A multistudy analysis reveals that evoked pain intensity representation is distributed across brain systems. PLoS Biol 20(5): e3001620. https://doi.org/10.1371/journal.pbio.3001620 von Kortzfleisch VT, Ambrée O, Karp NA, Meyer N, Novak J, Palme R, et al. (2022) Do multiple experimenters improve the reproducibility of animal studies? PLoS Biol 20(5): e3001564. https://doi.org/10.1371/journal.pbio.3001564

8. 

   7 Jun 2022

   Herpes for the Future

   Episode 4 of the monthly podcast CellOut, where your favorite pair of biology nerds, Derek DeVries and Ford Fishman, summarize and discuss a sample of articles from the April 2022 issue of PLoS biology. Issue Link: https://journals.plos.org/plosbiology/issue?id=10.1371/issue.pbio.v20.i04 Keywords: biology, life science, open access, scientific journals, science, PLoS, transmissible vaccines, evolution SHOW NOTES Podcast Art - Credit Caroline DeVries Episode Cover Art - April 2022 PLoS Biology Cover. Image Credit: Muthugapatti Kandasamy, Adam Sateriale, and Boris Striepen Cutting Edge (0:57) Cheng L, Mishra H (2022) Why did only one genus of insects, Halobates, take to the high seas? PLoS Biol 20(4): e3001570. https://doi.org/10.1371/journal.pbio.3001570 Jargon Jungle (11:12) Thanks to Josh for coming on the show! You can find him on twitter @PippettuaJones Reply the Episode 4 announcement by @CellOutPodcast with the keyword "Macrolide" if you want to prove you can handle the Jargon Jungle next episode! Journal Club (20:15) Griffiths ME, Broos A, Bergner LM, Meza DK, Suarez NM, da Silva Filipe A, et al. (2022) Longitudinal deep sequencing informs vector selection and future deployment strategies for transmissible vaccines. PLoS Biol 20(4): e3001580. https://doi.org/10.1371/journal.pbio.3001580 Cell Culture (36:56) Elden Ring - https://en.bandainamcoent.eu/elden-ring/elden-ring Benkarim O, Paquola C, Park B-y, Kebets V, Hong S-J, Vos de Wael R, et al. (2022) Population heterogeneity in clinical cohorts affects the predictive accuracy of brain imaging. PLoS Biol 20(4): e3001627. https://doi.org/10.1371/journal.pbio.3001627 Bite-Size Discoveries (42:21) Ciesielski HM, Nishida H, Takano T, Fukuhara A, Otani T, Ikegawa Y, et al. (2022) Erebosis, a new cell death mechanism during homeostatic turnover of gut enterocytes. PLoS Biol 20(4): e3001586. https://doi.org/10.1371/journal.pbio.3001586 Derosiere G, Thura D, Cisek P, Duque J (2022) Hasty sensorimotor decisions rely on an overlap of broad and selective changes in motor activity. PLoS Biol 20(4): e3001598. https://doi.org/10.1371/journal.pbio.3001598 Simonetti B, Guo Q, Giménez-Andrés M, Chen K-E, Moody ERR, Evans AJ, et al. (2022) SNX27–Retromer directly binds ESCPE-1 to transfer cargo proteins during endosomal recycling. PLoS Biol 20(4): e3001601. https://doi.org/10.1371/journal.pbio.3001601 English ED, Guérin A, Tandel J, Striepen B (2022) Live imaging of the Cryptosporidium parvum life cycle reveals direct development of male and female gametes from type I meronts. PLoS Biol 20(4): e3001604. https://doi.org/10.1371/journal.pbio.3001604

9. 

   3 May 2022

   Sinking to Success

   Episode 3 of the monthly podcast CellOut, where your favorite pair of biology nerds, Derek DeVries and Ford Fishman, summarize and discuss a sample of articles from the March 2022 issue of PLoS biology. Issue Link: https://journals.plos.org/plosbiology/issue?id=10.1371/issue.pbio.v20.i03 Keywords: biology, life science, open access, scientific journals, science, PLoS, experimental evolution, neuroscience, SHOW NOTES Podcast Art - Credit Caroline DeVries Episode Cover Art - March 2022 PLoS Biology Cover. Image Credit - Betül Yücel Cutting Edge (1:07) Pariente N, on behalf of the PLOS Biology Staff Editors (2022) Premiering pre-registration at PLOS Biology. PLoS Biol 20(3): e3001611. https://doi.org/10.1371/journal.pbio.3001611 Jargon Jungle (10:07) Special thanks to Dillon Martin, you were great! Journal Club (18:34) Dudin O, Wielgoss S, New AM, Ruiz-Trillo I (2022) Regulation of sedimentation rate shapes the evolution of multicellularity in a close unicellular relative of animals. PLoS Biol 20(3): e3001551. https://doi.org/10.1371/journal.pbio.3001551 Experimental Evolution Video: https://www.youtube.com/watch?v=plVk4NVIUh8&ab_channel=HarvardMedicalSchool Cell Culture (36:42) The Expanse - James S. A. Corey, TV adaptation on Amazon Prime Jang KK, Kaczmarek ME, Dallari S, Chen Y-H, Tada T, Axelrad J, et al. (2022) Variable susceptibility of intestinal organoid–derived monolayers to SARS-CoV-2 infection. PLoS Biol 20(3): e3001592. https://doi.org/10.1371/journal.pbio.3001592 Bite-Size Discoveries (42:08) Sun DS, Kissler SM, Kanjilal S, Olesen SW, Lipsitch M, Grad YH (2022) Analysis of multiple bacterial species and antibiotic classes reveals large variation in the association between seasonal antibiotic use and resistance. PLoS Biol 20(3): e3001579. https://doi.org/10.1371/journal.pbio.3001579 Vincent MS, Comas Hervada C, Sebban-Kreuzer C, Le Guenno H, Chabalier M, Kosta A, et al. (2022) Dynamic proton-dependent motors power type IX secretion and gliding motility in Flavobacterium. PLoS Biol 20(3): e3001443. https://doi.org/10.1371/journal.pbio.3001443 Jiang M, Shin J, Simeon R, Chang J-Y, Meng R, Wang Y, et al. (2022) Structural dynamics of receptor recognition and pH-induced dissociation of full-length Clostridioides difficile Toxin B. PLoS Biol 20(3): e3001589. https://doi.org/10.1371/journal.pbio.3001589 Rosen BQ, Halgren E (2022) An estimation of the absolute number of axons indicates that human cortical areas are sparsely connected. PLoS Biol 20(3): e3001575. https://doi.org/10.1371/journal.pbio.3001575

10. 

    5 Apr 2022

    A Little Bit Meta

    Episode 2 of the monthly podcast CellOut, where we summarize and discuss a sample of articles from the February 2022 issue of PLoS biology. Issue Link: https://journals.plos.org/plosbiology/issue?id=10.1371/issue.pbio.v20.i02 Keywords: biology, life science, open access, scientific journals, science, PLoS, ocean acidification, meta-analysis SHOW NOTES Podcast Art - Credit Caroline DeVries Episode Cover Art - February 2022 PLoS Biology Cover. Image Credit - Fredrik Jutfelt Cutting Edge (0:43) Pollack R, Cobb M (2022) Are there any good experiments that should not be done? PLoS Biol 20(2): e3001539. https://doi.org/10.1371/journal.pbio.3001539 Jargon Jungle (09:11) Journal Club (18:05) Clements JC, Sundin J, Clark TD, Jutfelt F (2022) Meta-analysis reveals an extreme “decline effect” in the impacts of ocean acidification on fish behavior. PLoS Biol 20(2): e3001511. https://doi.org/10.1371/journal.pbio.3001511 Cell Culture (35:09) Outer Wilds - https://www.mobiusdigitalgames.com/outer-wilds.html Bite-Size Discoveries (53:19) Abdill RJ, Adamowicz EM, Blekhman R (2022) Public human microbiome data are dominated by highly developed countries. PLoS Biol 20(2): e3001536. https://doi.org/10.1371/journal.pbio.3001536 Chang C-c, Cox DTC, Fan Q, Nghiem TPL, Tan CLY, Oh RRY, et al. (2022) People’s desire to be in nature and how they experience it are partially heritable. PLoS Biol 20(2): e3001500. https://doi.org/10.1371/journal.pbio.3001500 Finch E, Lowe R, Fischinger S, de St Aubin M, Siddiqui SM, Dayal D, et al. (2022) SARS-CoV-2 antibodies protect against reinfection for at least 6 months in a multicentre seroepidemiological workplace cohort. PLoS Biol 20(2): e3001531. https://doi.org/10.1371/journal.pbio.3001531 Vanderplow AM, Kermath BA, Bernhardt CR, Gums KT, Seablom EN, Radcliff AB, et al. (2022) A feature of maternal sleep apnea during gestation causes autism-relevant neuronal and behavioral phenotypes in offspring. PLoS Biol 20(2): e3001502. https://doi.org/10.1371/journal.pbio.3001502 Otte WM, Vinkers CH, Habets PC, van IJzendoorn DGP, Tijdink JK (2022) Analysis of 567,758 randomized controlled trials published over 30 years reveals trends in phrases used to discuss results that do not reach statistical significance. PLoS Biol 20(2): e3001562. https://doi.org/10.1371/journal.pbio.3001562

11. 

    14 Mar 2022

    Pilot

    A little rough around the edges but still covering some pretty cool science, it’s our pilot episode of CellOut! Here we summarize and discuss a sample of articles from the January 2022 issue of PLoS biology. Issue Link: https://journals.plos.org/plosbiology/issue?id=10.1371/issue.pbio.v20.i01 Keywords: biology, life science, open access, scientific journals, science, PLOS, SHOW NOTES Cover Art - January 2022 PLoS Biology Cover. Image Credit - Katie Chu Cutting Edge (01:46) Rocha EPC, Bikard D (2022) Microbial defenses against mobile genetic elements and viruses: Who defends whom from what? PLoS Biol 20(1): e3001514. https://doi.org/10.1371/journal.pbio.3001514 Crash Course (10:11) Coughlan J (2022) One fish, two fish, red fish, dead fish: Detecting the genomic footprint of ecological incompatibilities. PLoS Biol 20(1): e3001504. https://doi.org/10.1371/journal.pbio.3001504 Jargon Jungle (21:58) Journal Club (28:01) Prat Y, Bshary R, Lotem A (2022) Modelling how cleaner fish approach an ephemeral reward task demonstrates a role for ecologically tuned chunking in the evolution of advanced cognition. PLoS Biol 20(1): e3001519. https://doi.org/10.1371/journal.pbio.3001519 Cell Culture (49:12) Children of Time - Adrian Tchaikovsky Slice of Life Science (53:19) Koonin EV, Makarova KS (2022) Evolutionary plasticity and functional versatility of CRISPR systems. PLoS Biol 20(1): e3001481. https://doi.org/10.1371/journal.pbio.3001481 Jasso GJ, Jaiswal A, Varma M, Laszewski T, Grauel A, Omar A, et al. (2022) Colon stroma mediates an inflammation-driven fibroblastic response controlling matrix remodeling and healing. PLoS Biol 20(1): e3001532. https://doi.org/10.1371/journal.pbio.3001532 Stubenrauch CJ, Bamert RS, Wang J, Lithgow T (2022) A noncanonical chaperone interacts with drug efflux pumps during their assembly into bacterial outer membranes. PLoS Biol 20(1): e3001523. https://doi.org/10.1371/journal.pbio.3001523 Furness AI, Venditti C, Capellini I (2022) Terrestrial reproduction and parental care drive rapid evolution in the trade-off between offspring size and number across amphibians. PLoS Biol 20(1): e3001495. https://doi.org/10.1371/journal.pbio.3001495 Slavov N (2022) Learning from natural variation across the proteomes of single cells. PLoS Biol 20(1): e3001512. https://doi.org/10.1371/journal.pbio.3001512

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