Cognition Therapeutics's “Conversations” series will feature virtual fireside chats with neuroscience experts who will discuss advances in the research and treatment of Alzheimer’s disease, dementia with Lewy bodies (DLB), and other age-related neurodegenerative conditions. All episodes are available to watch as video as cogrx.com/conversations.
Episode 10: Studying the Patient-Caregiver Lived Experience in Dementia with Lewy Bodies
Brendan Kelley interviews Samantha K. Holden, and Carla Preyer, along with Linda Szypula about the lived experiences of patients and their caregivers navigating the challenges of Dementia with Lewy Bodies.
23 Oct 2024
Episode 9: Executing Clinical Research in Dementia with Lewy Bodies (DLB)
Featuring:
Anthony Caggiano, M.D., Ph.D. (moderator), Cognition Therapeutics, Chief Medical Officer
James E. Galvin, MD, MPH, University of Miami, Director of the Comprehensive Center for Brain Health, Miller School of Medicine
Lawrence S. Honig, MD, PhD, FAAN, Columbia University, Professor of Neurology, Irving Medical Center
David Shprecher, D.O., Banner Sun Health Research Institute, Movement Disorder Director, Banner Sun Health
Clinical Associate Professor, University of Arizona
Index:
0:00 Introduction
0:45 Comparing Alzheimer’s disease and DLB
5:02 SHIMMER Design and Outcomes
10:22 Metrics for Success in a Signal-finding Study
23 May 2024
Episode 8: Protecting the Synapse from Amyloid Toxicity in Alzheimer’s Disease
Featuring:
Anthony Caggiano, M.D., Ph.D. (moderator)
Cognition Therapeutics, Chief Medical Officer
Mary Hamby, Ph.D. (moderator)
Cognition Therapeutics, Vice President of Research
Everard (Jort) Vijverberg, MD, PhD
Alzheimer Center at Amsterdam University Medical Center, Neurologist and CNS Trial Specialist
Tara Spires Jones, DPhil
University of Edinburgh, Personal Chair of Neurodegeneration and Deputy Director of the Centre for Discovery Brain Sciences
Index:
0:00 Introduction
3:49 Findings from SEQUEL
6:45 Clinical observations of CT1812 engagement
9:08 Proteomic evidence of CT1812 engagement
11:52 CT1812’s ongoing Phase 2 study
21 Nov 2023
Episode 7: Quantitative EEG: Effects of CT1812 on Measures of Synaptic Function in Alzheimer’s Disease
Featuring:
Anthony Caggiano, M.D., Ph.D. (moderator), Cognition Therapeutics, Chief Medical Officer
Willem de Haan, M.D., Ph.D., Alzheimer Center at Amsterdam University Medical Center, Neurologist and Senior Researcher
Philip Scheltens, M.D., EQT Life Sciences, Partner and Head of Dementia Fund, Former Director of the Alzheimer Center at Amsterdam University Medical Center
Index:
0:00 Introduction
0:44 Rationale for the SEQUEL Study Design
2:10 EEG in neurodegenerative diseases
4:33 Findings from SEQUEL
9:52 Key Takeaways
20 Sept 2023
Episode 6: Geographic Atrophy: New Strategies to Protect the Retina
Featuring:
Anthony Caggiano, M.D., Ph.D., Chief Medical Officer, Cognition Therapeutics
C. Gustavo De Moraes, M.D., Ph.D. (moderator), Chief Medical Officer, Ora (CRO), and Associate Professor of Clinical Ophthalmology, Columbia University
Jeffrey S. Heier, M.D., Director of the Vitreoretinal Service & Retina Research, Ophthalmic Consultants of Boston
Peter K. Kaiser, M.D., Chaney Family Endowed Chair in Ophthalmology Research and Professor of Ophthalmology, Cleveland Clinic Lerner College of Medicine
25 May 2023
Episode 5: Exploring the Effects of CT1812 on Alzheimer’s Disease Processes: Biomarkers and Pathways of Neurodegeneration
Featuring:
Mary Hamby, Ph.D., Vice President of Research, Cognition Therapeutics
Charlotte Teunissen, Ph.D. (moderator), Amsterdam University Medical Center, Professor of Clinical Neurochemistry
Nicholas Seyfried, Ph.D., Emory University School of Medicine, Professor of Biochemistry and Neurology , Director of the Emory Integrated Proteomics Core
Henrik Zetterberg, MD, Ph.D., Gothenburg University, Professor of Neuroscience
Group Leader of the UK Dementia Research Institute
Index:
0:00 Introduction
01:53 Utility of Proteomic Analysis in Alzheimer’
03:20 Review of Proteomics Findings from AD/PD 202
08:36 Key Learnings
25 May 2023
Episode 4: Insights for the Primary Care Physician: Recognizing Dementia with Lewy Bodies
Featuring:
Anthony Caggiano, M.D., Ph.D., Chief Medical Officer and Head of Research & Development, Cognition Therapeutics
Brendan Kelley, M.D. (moderator), University of Texas SW, Vice Chair for Clinical Operations at the Peter O’Donnell Jr. Brain Institute and a Professor in the Department of Neurology
Sarah B. Berman, M.D., Ph.D., University of Pittsburgh, Associate Professor in the Departments of Neurology and Clinical & Translational Science and Director of DLB Programs at the ARDC
James Leverenz, M.D., Cleveland Clinic, Director of the Lou Ruvo Center for Brain Health
David Shprecher, D.O., Banner Sun Health Research Institute, Movement Disorder Director
University of Arizona, Clinical Associate Professor
Index:
0:00 Introduction
01:09 Part I: The Intersection of Alzheimer’s and DLB
07:23 Biomarker Tests for DLB
09:11 Part II: Practical insights for community HCPs
09:40 Frequency of missed or delayed diagnosis of DLB
12:48 Facets of patient-reported memory loss
19:46 Nuances of psychological symptoms
24:23 Cognitive Fluctuations
25 May 2023
Episode 3: What if it’s not Alzheimer’s? The Caregiver’s Perspective on Lewy Body Dementia
Featuring:
Lisa Ricciardi, President & Chief Executive Officer, Cognition Therapeutics
Norma Loeb, Lewy Body Dementia Resource Center, Founder and Executive Director
Mary Lou Falcone, M.L. FALCONE, Public Relations
Board member, LBD Resource Center
Author of “I Didn’t See It Coming, a Memoir of Love, Loss, and Lewy Body Dementia”
Index:
0:00 Introduction
2:30 Key symptoms and signs of Lewy body dementia
9:44 The importance of an accurate diagnosis
13:30 Preparing for a doctor visit
15:30 Resources, support and caring for the caregiver
25 May 2023
Episode 2: Building on Amyloid Lowering: Key Insights from Recent Data and Prospects for Complementary Therapeutic Approaches
Featuring:
Anthony Caggiano, M.D., Ph.D., Chief Medical Officer and Head of R&D, Cognition Therapeutics
Christopher H. van Dyck, M.D., Yale University School of Medicine, Professor of Psychiatry, Neurology, and Neuroscience
Director of the Division of Aging and Geriatric Psychiatry; Director of the Alzheimer’s Disease Research Center
Anton P. Porsteinsson, M.D., University of Rochester School of Medicine and Dentistry, William B. and Sheila Konar Professor of Psychiatry, Neurology, Neuroscience, and Medicine
Director of the Alzheimer’s Disease Care, Research and Education Program (AD-CARE)
Index:
0:00 Introduction
1:47 Reactions to lecanemab results
3:48 Impact of targeting plaque
6:46 Potentially complementary strategies
11:24 Future of Alzheimer’s therapies
13:40 Conclusion
25 May 2023
Episode 1: Dementia with Lewy Bodies
Featuring:
Anthony Caggiano, M.D., Ph.D., Chief Medical Officer and Head of R&D, Cognition Therapeutics
James Galvin, M.D., MPH, University of Miami Miller School of Medicine, Director of the Comprehensive Center for Brain Health
Principal Investigator of the SHIMMER Study
Index:
0:00 Introduction
1:09 What is DLB
3:13 Diagnostic Challenges
6:38 Potential Treatment Strategy
7:48 Designing a Clinical Trial
8:42 Conclusion
Who has been a guest on Cognition Conversations
Names identified in recent episode analyses. Showing up to five guests.
Samantha K Holden
Carla Preyer
Linda Szypula
Reach and audience
Public platform figures. Ratings count people who left a rating, not total listeners.
Apple Podcasts (US)
4.5 / 5
2 ratings
Podcast Authority Score: 15 / 100
A composite of feed quality, social presence, YouTube performance and engagement. Read the methodology.
Quality
17
Social presence
0
YouTube
0
Engagement
32
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