”de-CIPHERing Infectious Disease” explores the cutting-edge interdisciplinary research happening at UNC Charlotte’s CIPHER Research Center. Each episode features an in-depth interview with one of CIPHER’s researchers, allowing them to discuss their background, current projects, and the exciting team science approach they take to tackle complex issues at the intersection of health, environment, data science, genomics, infectious disease, and more. Host Ian Binns engages the researchers in accessible conversations that dive into the science behind their work while also highlighting the collaborative spirit and diverse expertise that makes CIPHER’s ”One Health” philosophy so powerful. From evolution and phylogenetics to machine learning, drug discovery, and preventing the next pandemic, ”de-CIPHERing Infectious Disease” offers listeners a window into the innovative solutions being pioneered to address global challenges.
de-CIPHERing Infectious Disease
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Podcast Overview
”de-CIPHERing Infectious Disease” explores the cutting-edge interdisciplinary research happening at UNC Charlotte’s CIPHER Research Center. Each episode features an in-depth interview with one of CIPHER’s researchers, allowing them to discuss their background, current projects, and the exciting team science approach they take to tackle complex issues at the intersection of health, environment, data science, genomics, infectious disease, and more. Host Ian Binns engages the researchers in accessible conversations that dive into the science behind their work while also highlighting the collaborative spirit and diverse expertise that makes CIPHER’s ”One Health” philosophy so powerful. From evolution and phylogenetics to machine learning, drug discovery, and preventing the next pandemic, ”de-CIPHERing Infectious Disease” offers listeners a window into the innovative solutions being pioneered to address global challenges.
Language
🇺🇲
Publishing Since
4/22/2024
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Recent Episodes
October 2, 2025
Life on the Edge with Laurel Yohe
Episode 13 What can we learn from animals that live life on the edge? Dr. Laurel Yohe joins the podcast to discuss her fascinating research on bats, creatures with extreme adaptations like supersonic echolocation and mysteriously resilient immune systems. The conversation explores how studying these unique animals, using everything from 100-year-old museum specimens to cutting-edge genomic sequencing, provides critical insights into evolution and the transmission of viruses. Dr. Yohe also makes a powerful case for "science for the sake of discovery," where pure curiosity can lead to the most unexpected and vital breakthroughs. Find out more at cipher.charlotte.edu. Key Takeaways Studying animals that live at biological extremes, such as in unique environments or with unusual metabolisms, provides a powerful window into the evolutionary pressures that create diversity. Modern research often finds success by creatively blending old and new scientific methods. For instance, basic tissue staining of a bat specimen from 1906 yielded images as clear as if the sample were fresh, showing the value of classic techniques. To optimize their "supersonic" echolocation abilities, the anatomy of horseshoe bats has been completely rearranged. Their throats have essentially moved up into their faces to fine-tune how they perceive the world through sound. Evolutionary adaptations for one purpose can have unintended consequences for other systems. The same changes that improved bat echolocation also altered the placement of immune cells in the nasal cavity, potentially affecting how they tolerate viruses. The risk of pathogens spreading from animals to humans increases as we encroach on wildlife habitats. This creates a greater interface between wild animals, domesticated animals, and people, raising the chances of a spillover event. Research driven by pure curiosity is essential because it can become unexpectedly vital. Foundational knowledge on bat noses, gathered simply out of scientific interest, suddenly became highly relevant during the COVID-19 pandemic. This podcast was produced and edited by Zack JacksonCIPHER is a proud part of UNC Charlotte who holds all rights to the content created by this podcast
February 11, 2025
Expanding the Genome with Dr. Danillo Augusto
Episode 12 In this conversation, Danilo shares his journey from Brazil to the US, detailing his experiences with the neglected autoimmune disease Pemphigus and his current research focus on genomic equity. He discusses the importance of studying underrepresented populations in genomics and the challenges faced in addressing health disparities. Find out more at cipher.charlotte.edu. Key Takeaways Pemphigus is a neglected autoimmune disease endemic to Brazil. Health disparities are evident in the lack of research on diseases affecting poor populations. Most genomic studies focus on European ancestry, creating gaps in understanding. Danilo secured a significant NIH grant to study Pemphigus. Understanding limitations leads to better scientific partnerships. Team science is essential for addressing complex research questions. Genetic variation in immune regions is often overlooked. SARS-CoV-2 research revealed strong genetic associations. Environmental factors can trigger health issues in populations. Future research should focus on underrepresented genetic regions. This podcast was produced and edited by Zack JacksonCIPHER is a proud part of UNC Charlotte who holds all rights to the content created by this podcast
January 30, 2025
Unraveling DNA with Dr. Abbe LaBella
Episode 11 Join us for an engaging conversation with Dr. Abbe LaBella, Assistant professor of Bioinformatics and Genomics at UNC Charlotte. She will take us along her journey from designing mailboxes to studying fungal genetics. Along the way, there will be deep sea adventures, genetic breakthroughs, and lessons for all stages of life. Find out more at cipher.charlotte.edu. Key Takeaways Abby actively mentors students from high school to postdoctoral levels. Her deep-sea research involved collecting samples using the submersible Alvin. Abby's lab focuses on understanding the implications of genomic variation. Silent mutations, once thought inconsequential, can influence disease outcomes. The field of codon usage bias is relatively new and evolving. Machine learning can uncover patterns in genetic data without bias. The importance of tRNAs in protein synthesis is often overlooked. The NIH grant will focus on understanding silent synonymous data in yeast. This podcast was produced and edited by Zack JacksonCIPHER is a proud part of UNC Charlotte who holds all rights to the content created by this podcast
13 total episodes available
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- What is de-CIPHERing Infectious Disease?
- How often does this podcast release new episodes?
This podcast updates bi-weekly.
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This podcast is available on 8 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.
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Yes, this podcast regularly features guests.
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