A podcast dedicated to unraveling the mysteries of aging through the lens of cutting-edge science. Each episode breaks down the latest research papers in the field of geroscience, offering clear, insightful discussions on longevity, biological aging, and the quest for extending healthspan. Perfect for scientists, enthusiasts, and anyone curious about the science behind living longer and healthier lives.
Decoding Longevity
Claim This Podcastby Raghav Sehgal
29 episodes
Updated Daily
Accepts GuestsHas Sponsors
Podcast Overview
A podcast dedicated to unraveling the mysteries of aging through the lens of cutting-edge science. Each episode breaks down the latest research papers in the field of geroscience, offering clear, insightful discussions on longevity, biological aging, and the quest for extending healthspan. Perfect for scientists, enthusiasts, and anyone curious about the science behind living longer and healthier lives.
Language
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Publishing Since
3/26/2025
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Recent Episodes
July 1, 2026
Longevity for Everyone: HIV, Prevention, and the Future of Global Healthy Aging — A Conversation with Professor Linda-Gail Bekker
<p>What if the greatest breakthrough in longevity isn't slowing aging—but preventing disease before it begins?</p><p>In this episode of <strong>Decoding Longevity</strong>, we speak with Professor <strong>Linda-Gail Bekker</strong>, one of the world's leading experts in HIV prevention, tuberculosis research, and global public health. Together, we explore how HIV research has transformed our understanding of longevity, from restoring life expectancy through antiretroviral therapy to preventing infection with groundbreaking advances like <strong>Lenacapavir</strong>.</p><p>We discuss healthspan versus lifespan, chronic inflammation, accelerated biological aging, health equity, and why prevention may be the most powerful longevity intervention of all. This conversation offers a compelling look at how advances in infectious disease research are shaping the future of healthy aging.</p>
June 10, 2026
What Can Hibernating Squirrels Teach Us About Aging, Disease, and Human Health?: A Conversation With Dr. Ashley Zehnder
<p>What can hibernating squirrels teach us about aging, disease, and human health?</p><p>In Episode 28 of Decoding Longevity, we sit down with Dr. Ashley Zehnder, Co-Founder and CEO of Fauna Bio, to explore how evolution-driven drug discovery is uncovering new therapeutic opportunities for some of humanity’s most challenging diseases.</p><p>Ashley explains how animals that naturally withstand oxygen deprivation, prevent fibrosis, rebuild tissues, and resist neurodegeneration may hold the key to future treatments for heart failure, metabolic disease, and age-related decline.</p><p>We discuss hibernation biology, comparative genomics, AI-powered drug discovery, regenerative medicine, and how nature’s most resilient species are helping scientists identify novel therapeutic targets.</p><p>Key topics include:</p><p>• Hibernation as a model for regeneration and tissue repair</p><p>• Comparative biology and longevity science</p><p>• AI, genomics, and evolution-driven drug discovery</p><p>• Brain resilience and neurodegenerative disease</p><p>• Heart failure therapeutics inspired by nature</p><p>• The future of biotechnology and healthy aging</p><p>Guest: Dr. Ashley Zehnder Co-Founder & CEO, Fauna Bio</p><p>Hosts: Dr. Raghav Sehgal & Dr. Macsue Jacques</p><p>Fauna Bio: https://www.faunabio.com/</p><p>Ashley’s Talks</p><ul><li>https://www.youtube.com/watch?v=WX-ulloH08w</li><li>https://www.youtube.com/watch?v=kmowQzL_VjY</li><li>https://www.youtube.com/watch?v=C9cy7vyTUGs</li></ul>
May 27, 2026
Metabolism, Immunity & the Biology of Aging: A Conversation with Dr. Eric Verdin
<p>What if aging is not just damage — but a biologically regulated process shaped by metabolism, inflammation, and gene expression?</p><p>In this episode of Decoding Longevity, Dr. Eric Verdin, President and CEO of the Buck Institute for Research on Aging, joins us for a wide-ranging conversation on the molecular biology of aging.</p><p>We explore how metabolism influences epigenetics, why immune aging may be central to healthspan, and what today’s longevity science actually tells us about extending healthy human life.</p><p>From NAD+ and ketone bodies to inflammaging, biomarkers, rapamycin, metformin, and epigenetic reprogramming, this episode breaks down some of the most important ideas shaping the future of longevity research.</p><p>We also discuss the growing hype surrounding longevity medicine — and why rigorous science, clinical trials, and evidence still matter.</p><p>Featuring:Dr. Eric VerdinHosted by Dr. Raghav Sehgal & Dr. Macsue Jacques</p><p>Follow Decoding Longevity for more conversations on aging biology, longevity science, AI, and the future of medicine.</p><p><br></p><p>Buck Institute of Aging: https://www.buckinstitute.org/</p><p>Eric Verdin's LinkedIn: https://www.linkedin.com/in/eric-verdin-490212/</p>
29 total episodes available
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Frequently asked questions
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- What is Decoding Longevity?
- How often does this podcast release new episodes?
This podcast updates daily.
- Where can I listen to this podcast?
This podcast is available on 4 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.
- Does this podcast accept guests?
Yes, this podcast regularly features guests.
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