A podcast dedicated to unraveling the mysteries of aging through the lens of cutting-edge science. Each episode breaks down the latest research papers in the field of geroscience, offering clear, insightful discussions on longevity, biological aging, and the quest for extending healthspan. Perfect for scientists, enthusiasts, and anyone curious about the science behind living longer and healthier lives.
What If Your "Normal" Isn't Your Normal? - A Conversation with Dr. Nathan Price
What if the future of medicine is not about what is “normal” for everyone, but what is normal for you?
In Episode 35 of Decoding Longevity, Raghav Sehgal sits down with Dr. Nathan Price to explore how AI, systems biology, and longitudinal health data could transform personalized medicine and the way we understand aging.
They discuss the N-of-1 approach, personal data clouds, multi-omics, genetic gap analysis, and how AI could help interpret the thousands of biological signals generated by a single person.
Nathan also explains the concept of digital twins in healthcare, why healthspan should become “measurable, predictable, and modifiable,” and how future AI systems could help us predict and continuously update individual health trajectories.
The conversation also covers health data privacy, scientific wellness, translating research into real-world products, and what the next 5–10 years could bring for longevity research and personalized health.
16 Sept 2026
Is Rapamycin Dead? — A Conversation with Matt Kaeberlein
What if we could slow biological aging itself—not just treat the diseases that come with it?
In Episode 34 of Decoding Longevity, Raghav Sehgal and Dr. Macsue Jacques sit down with Professor Matt Kaeberlein to explore the biology of aging and what it might mean to actually intervene in the aging process.
They discuss mTOR and rapamycin, the debate around rapamycin in humans, and why Matt believes some recent evidence has been misunderstood. The conversation also covers the Dog Aging Project, the TRIAD trial, Aura Biomedical, AI-powered lifespan research, and the future of longevity biotech.
From yeast and worms to dogs and humans, this episode explores how we can move from understanding aging to potentially changing it.
4 Sept 2026
Can a Shingles Vaccine Slow Down Dementia? Survival, Cognitive Preservation, and Immune Modulation
Could a shingles vaccine also influence dementia?
In Episode 33 of Decoding Longevity, Dr. Raghav Sehgal and Dr. Macsue Jacques are joined by Dr. Moshe Shay Ben-Haim to explore his team’s findings linking the Shingrix vaccine with improved survival and cognitive preservation in people living with dementia.
They discuss trained immunity, latent viruses, epigenetics, and what this surprising connection could mean for the future of neurodegeneration and longevity research.
Importantly, the findings are observational and do not establish Shingrix as a treatment for dementia.
Contact Decoding Longevity
Guest appearances
Books guests
Based on episode analysis; this does not confirm that the show is currently accepting guests.
Host of Decoding Longevity?
Claim your podcast to manage its listing and keep your show details accurate.
Pod Engine is an independent podcast discovery and analytics service and is not affiliated with or endorsed by this podcast. Artwork and show content belong to their owners. Full legal notice.
Explore this show Podcast research with Pod Engine
