This is the Podcast of the European Society for Molecular Imaging (ESMI).
Join us as we delve into the recent literature, and perhaps learn a little from the minds that have shaped the field.
The premise is really simple: Each time we invite one senior academic to discuss their favourite publication from the recent literature. We’ll find out what caught their eye, and why it is worth taking a closer look at this particular publication. Along the way, we will learn their publication strategies and possibly even glimpse into the future of this amazing field of research.
Music “In this Life”, Composer: Guido Jäger, Musicians: Andreas Jacobs – violin, Jacob Niller – accordion, Wolfgang Platen – contrabass
Bioadhesive ultrasound for long-term continuous imaging of diverse organs
GUEST: Metin Sitti, Koç University IstanbulWelcome to Episode 18 of “Dive into Imaging Science”! 🎧 Tune in to hear from an inspirational figure and explore how medical devices – whether implanted or intravenously administered – are set to transform the world we live in.. In this edition, we are delighted to introduce a pioneer in the field of bio-inspired miniature robots: Metin Sitti. A recurring theme across many of our episodes is the importance of working in a curious and inspiring enviro...
5 Sept 2025
[177Lu]Lu-DOTA-TATE plus long-acting octreotide versus high‑dose long-acting octreotide for the treatment of newly diagnosed, advanced grade 2–3, well-differentiated, gastroenteropancreatic neuroendocrine tumours
GUEST: Rodney Hicks, MelbourneWelcome to Episode 17 of “Dive into Imaging Science”! 🎧 Tune in for a dynamic discussion on how NETTER-2 may reshape treatment strategies for neuroendocrine tumours, what it means for the wider field of theranostics, and where radioligand therapy is headed next. For our seventeenth edition, we are at the stunning Certosa di Pontignano in Tuscany – the home of TOPIM, which focussed this year on Theranostics. 🎯 Suitably, we discuss one of the most important r...
23 Jul 2025
In vivo multiplex imaging of dynamic neurochemical networks with designed far-red dopamine sensors
GUEST: Markita Del Carpio Landry, UC BerkeleyWelcome to Episode 16 of “Dive into Imaging Science”! 🎧 Tune in for a dynamic discussion on innovative probes work, the function of dopamine in the brain, and how these new imaging tools can be used in the future to reveal new biology. This episode features a truly special guest: Markita Del Carpio Landry, the inaugural Trailblazer Plenary Lecturer at the upcoming EMIM in Ljubljana next March! "The Trailblazer Lecture celebrates a rising lead...
2 Jun 2025
In Vivo Assessment of Deep Vascular Patterns in Murine Colitis Using Optoacoustic Mesoscopic Imaging
Vasilis Ntziachristos discusses the revolutionary use of light and sound interplay to assess deep vascular patterns in murine colitis using optoacoustic mesoscopic imaging in this interview.
2 May 2025
Development of a 213Bi-Labeled Pyridyl Benzofuran for Targeted α-Therapy of Amyloid-β Aggregates
GUEST: Peter J.H. Scott, University Michigan (Ann Arbor)🎙️ Welcome to Episode 14 of "Dive into Imaging Science"! In this edition, we’re thrilled to welcome a very special guest: Peter Scott! Peter’s passion for radiochemistry and his dedication to translating research into clinical applications have made a lasting impact on the field of Theranostics – also the central theme of this year’s TOPIM (don’t forget to check it out!). By following Peter’s inspiring career journey, we gain valua...
18 Dec 2024
Achieving optical transparency in live animals with absorbing molecules
Fabian Kiessling, president of the Institute of Experimental Molecular Imaging and Helmholtz Institute for Biomedical Engineering, reveals how absorbing molecules achieve optical transparency in live animals.
2 Dec 2024
Transthoracic ultrasound localization microscopy of myocardial vasculature in patients
Elisa Konofagou shares her pioneering ultrasound imaging techniques for visualizing heart and vessel biology, unlocking super-resolution imaging of myocardial microvasculature in patients.
23 Oct 2024
Long-term engraftment and maturation of autologous iPSC-derived cardiomyocytes in two rhesus macaques
GUEST: John Ronald, London (ON, Canada)Welcome back! It has been a while but are back with a bang, having our good friend John Ronald from The Robarts Research Institute in London, Ontario as our guest. John’s group combines advances in molecular and synthetic biology with a multimodal imaging perspective to build new tools for early detection and treatment of cancer, as well as non-invasive monitoring of cell, gene and genome therapies. One of John’s passions is gene reporter imag...
21 Dec 2023
In vivo imaging of cerebral glucose metabolism informs on subacute to chronic post-stroke tissue status - A pilot study combining PET and deuterium metabolic imaging
GUEST: Kevin Brindle, CambridgeIn this episode we welcome the one and only Kevin Brindle from University of Cambridge.During his long and illustrious career, Kevin pioneered hyperpolarized magnetic resonance spectroscopy as a method to map metabolic flux in cancer and other diseases, with implications for treatment response monitoring.We explore how deuterium imaging and [18F]FDG PET can be used to track the metabolic changes that occur soon after stroke and during the recovery phase. We disc...
6 Oct 2023
Visualizing cell–cell communication using synthetic notch activated MRI
GUEST: Mikhail Shapiro, PasadenaIn this episode we welcome our famous guest Mikhail Shapiro from Caltech. Mikhail exquisitely combines ultrasound with synthetic biology for gene regulation, imaging, and therapy - and Synthetic biology is surely the common thread in this podcast edition.We discover how an engineered receptor and an intracellular signalling domain, known as ‘synNotch’ can be used to visualise cell-cell communication in vivo. And how this system can be used to identify immune-ca...
29 Aug 2023
Albumin-Binding and Conventional PSMA Ligands in Combination with 161Tb
GUEST: Jason Lewis, New YorkIn this episode we discuss and learn about new PSMA-binding ligands with 161Tb, their biodistribution, dosimetry, preclinical therapy, and their comparison with conventional PSMA ligands. Our guest is one of the leading scientists in radiochemistry for cancer detection and therapy, the wonderful Jason Lewis. We talk about the importance of using 161Tb - this novel radionuclide for radioligand therapy - and its favorable decay characteristics as compared to 177...
5 Jul 2023
Glymphatic influx and clearance are accelerated by neurovascular coupling
GUEST: Annemie Van Der Linden, AntwerpIn this edition of ‘Dive into Imaging Science’ we discuss the brain and the mechanisms that it employs to clear unwanted waste material whilst we sleep with our former ESMI President and Emeritus Professor Annemie Van Der Linden - an outstanding figure and incomparable scientist.We learn how closely coupled this system - known as the glymphatics - is to blood circulation, and how physical stimulation can enhance glymphatic flow in anaesthetised but not aw...
1 Jun 2023
First-in-human study of the radioligand 68Ga-N188 targeting nectin-4 for PET/CT imaging of advanced urothelial carcinoma
GUEST: Elisabeth de Vries, GroningenIn this episode we talk about nectin-4 - an emerging biomarker for cancer diagnosis and therapy - with one of the most influential and distinguished scientists in medical oncology, Elisabeth de Vries. We talk about the first-in-human study of a radioligand that can target nectin-4 and learn what medical oncologists need to get out from imaging data so that these powerful tools continue to make an impact on patient outcomes. We learn about the importance and...
18 Apr 2023
Development of a Lensless Radiomicroscope for Cellular-Resolution Radionuclide Imaging
GUEST: Bernd Pichler, TübingenIn this episode we learn how a new lensless microscope, costing just $100 (!), can be used to evaluate radiotracer retention in cells, and discuss potential applications for this revolutionary new technology with our famous guest Bernd Pichler. We discuss how this, and other technologies, could be used to assess the heterogeneous cell populations of the tumour microenvironment and identify cell senescence using new radiotracers developed in Bernd’s lab.Selected P...
10 Feb 2023
Design and characterization of fibroblast activation protein targeted pan-cancer imaging agent for fluorescence-guided surgery of solid tumors
GUEST: Zaver Bhujwalla, BaltimoreIn this episode we discuss how targeting fibroblasts rather than tumour cells may be an effective strategy for both surgical guided resection and as an anti-cancer therapy with Tim’s “academic grandmother”, Zaver Bhujwalla. We discovered Zaver’s roots as a physicist and mathematician, learned about her (unpredictable) interest in cancer metabolism and how she combines tools to develop a powerful in vitro diagnostic test.Selected Publication: "Design and charac...
6 Dec 2022
Multiplexed bioluminescence imaging with a substrate unmixing platform
GUEST: Clemens C.W.G. Lowik, RotterdamIn this episode we discuss and learn about Bioluminescence Imaging and modern tools for multiplexed imaging of different colors, tackling a major challenge of the field. Our guest is one of the founding fathers of the ESMI and pioneers on multicolor BLI, the one and only Clemens Lowik. We talk about innovative approaches for unmixing multiple luciferase-luciferin pairs and quantitative analyses of bioluminescent mixtures, enabling serial tracking of...
2 Nov 2022
Positronium imaging with the novel multiphoton PET scanner
GUEST: Simon Cherry, UC DavisIn this episode we discuss (and learn a lot about!) positronium imaging with the co-inventor of Total Body PET, the wonderful Simon Cherry, the physics behind positronium formation, and how it might provide further biological information than standard positron emission tomography imaging. We learnt about Simon’s journey that led him to change the field of clinical PET imaging and what new innovations he has up his sleeve... and if you are looking for a research ar...
5 Sept 2022
Imaging of nanoparticle-labeled CAR T cells
GUEST: Jolanda de Vries, NijmegenIn this episode the hosts Tim and Giannis talk with the fantastic Jolanda De Vries from Nijmegen about how dendritic cell therapy got her into imaging and the latest therapeutic cell imaging methods. We touch on multimodality imaging, why imaging isn’t frequently used in the clinic for cell tracking, and why mouse models of cancer might never be good enough.Selected Publication: "In vivo imaging of nanoparticle-labeled CAR T cells" published in Proceedings of ...
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Apple Podcasts (US)
3.5 / 5
2 ratings
Spotify
4.2 / 5
5 ratings
Podcast Authority Score: 13 / 100
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14
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YouTube
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Engagement
31
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