Don't Just Read the Guidelines

About Don't Just Read the Guidelines

A podcast about blood giving awesome, upcoming medics and scientists a platform to discuss new advances and express their opinions.

Category

science

Language

en

Explicit

No

First episode

28 May 2021

Latest episode

26 May 2024

Latest episodes

24 episodes in the feed.

1. 

   26 May 2024

   Don't Just Read the Abstract: VITT & HIT

   In this episode, Rich and Pip discuss vaccine-induced immune thrombotic thrombocytopenia and heparin-induced thrombocytopenia. They critique a recent paper that has shown that VITT has been around before vaccines against Covid-19. Importantly, they discuss which patients should be tested for spontaneous VITT- and HIT-like syndromes, and discuss a recent case. The paper is: Schönborn L. et al. Anti-PF4 immunothrombosis without proximate heparin or adenovirus vector vaccine exposure. Blood. 2023 Dec 28;142(26):2305-2314.

2. 

   10 Mar 2024

   DJRTA Ep2 V6

   In this episode, Pip and Rich discuss the FRAIL-AF study: Joosten et al. Safety of Switching From a Vitamin K Antagonist to a Non–Vitamin K Antagonist Oral Anticoagulant in Frail Older Patients With Atrial Fibrillation: Results of the FRAIL-AF Randomized Controlled Trial. Circulation. 2024;149:279–289. This trial randomised the switching of elderly frail patients who were established on a vitamin K antagonist to either remain on this treatment or switch to a direct oral anticoagulant. They found increased rates of bleeding in the switch arm. However, there is a lot of detail that is not in the abstract! Pip and Rich take a deep dive into the manuscript, discuss their thoughts with Chief Investigator, Geert Jan Geersing on the trial, and put the findings into context with consultant haematologist David Sutton. To read more about this trial check out Rich's blog on it: https://classicalcompass.substack.com/p/frail-af Links FRAIL-AF: https://www.ahajournals.org/doi/epdf/10.1161/CIRCULATIONAHA.123.066485

3. 

   4 Feb 2024

   Don't Just Read the Abstract: The PACER Trial

   In this, the first episode of a new podcast, "Don't Just Read the Abstract", Drs Pip Nicolson and Rich Buka take a deep dive into the PACER trial: Platelet Transfusion before CVC Placement in Patients with Thrombocytopenia. After a quick round up of other trials that have sparked their interest, Pip and Rich discuss about the study aims and outcomes, before interviewing Dr Floor van Baarle, lead study author before discussing the clinical implications of the trial with Prof Simon Stanworth. Follow Pip, Rich, and HaemSTAR on X/Twitter: @PipNicolson, @RichardBuka, and @HaemSTAR_UK To claim CPD credits, please email haemstarnetwork@gmail.com. Links - van Baarle et al. Platelet Transfusion before CVC Placement in Patients with Thrombocytopenia. NEJM, 2023. - Matsushita et al. Phase 3 Trial of Concizumab in Hemophilia with Inhibitors (explorer7). NEJM, 2023. - Joosten et al. Safety of Switching from a Vitamin K Antagonist to a Non-Vitamin K Antagonist Oral Anticoagulant in Frail Older Patients with Atrial Fibrillation: Results of the FRAIL-AF Randomized Controlled Trial. Circulation, 2023. - Warkentin et al. Adenovirus-Associated Thrombocytopenia, - Thrombosis, and VITT-like Antibodies. NEJM, 2023 - Zhao et al. Intracerebral Hemorrhage Among Blood Donors and Their Transfusion Recipients. JAMA, 2023 HaemSTAR is an independent UK-wide network of registrars in clinical haematology, interested in promoting and performing research in classical haematology. Our focus is on collaborative projects across haemostasis & thrombosis, transfusion, general haematology, and obstetric haematology. This episode was sponsored by Sobi as a hands-off educational grant. Sobi had no editorial input whatsoever. Produced by Joe Apperley. All rights reserved.

Reach and audience

Public platform figures. Ratings count people who left a rating, not total listeners.

Apple Podcasts (US)

5.0 / 5

2 ratings

Spotify

5.0 / 5

4 ratings