Editors at eClinicalMedicine, in conversation with the journal’s authors, explore their latest research and its impact on people’s health, healthcare, and health policy.A monthly audio companion to this open access journal, this podcast covers a broad range of topics, from maternal health in the perinatal period and beyond to access to cancer care for people experiencing homelessness, the impact of weight bias in health care to oral treatments for MRSA skin infections, and more.
Saul Faust on SPVX02, room-tempature-stabilised tetanus-diptheria vaccine
Saul Faust joins Senior Editor Owen Stretton to talk about his team’s phase 1 trial on SPVX02, a lyophilised, fridge-free version of the Tetadif tetanus-diphtheria vaccine, and its potential in increasing vaccination coverage.
Click here to read the full article:
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(26)00369-X/fulltext
6 Aug 2026
Is Europe ready for organised, risk-stratified prostate cancer screening?
Prostate cancer is the most commonly diagnosed cancer among men in Europe, and momentum is growing behind organised screening programmes that use prostate-specific antigen (PSA) testing alongside risk stratification and MRI to improve the balance between benefits and harms. However, introducing a screening programme requires more than clinical expertise. Health systems must also have the infrastructure, data systems, quality assurance mechanisms, and follow-up pathways needed to support effective implementation. In this episode, Dr Arunah Chandran joins eClinicalMedicine Senior Editor Sundus Ahmad to discuss a new study from the PRAISE-U (PRostate cancer Awareness and Initiative for Screening in the European Union) project. Drawing on readiness assessments across five pilot sites in Lithuania, Poland, Spain, and Ireland, the study evaluates whether health systems are prepared to deliver organised, risk-stratified prostate cancer screening. Together, they explore why strong clinical capacity alone may not be enough, highlighting gaps in invitation systems, counselling, quality assurance, data management, and long-term follow-up. This conversation examines what is needed to move from opportunistic testing to population-based screening and what lessons these findings offer for the future of prostate cancer early detection in Europe.
Click here to read the full papers:
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00601-1/fulltext
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(26)00346-9/fulltext
15 Jul 2026
Ilaria Costantini on GLP-1 receptor agonists and binge eating
Could GLP-1 receptor agonists be used to treat binge eating disorder? Binge eating disorder is one of the most common eating disorders, yet treatment options remain limited. Now widely used for type 2 diabetes and weight management, Glucagon-like peptide (GLP)-1 receptor agonists act on pathways involved in appetite and food intake, but little is known about how these medications affect disordered eating behaviours, including binge eating, emotional eating, loss of control eating, and dietary restraint.
In this episode, Dr Ilaria Costantini joins eClinicalMedicine Senior Editor Victoria Higgs to discuss her new systematic review and meta-analysis, which draws on data from 25 clinical trials and more than 8000 participants, alongside valuable personal insights from people with lived experience. They explore evidence that GLP-1 receptor agonists may reduce binge eating-related behaviours, while also considering concerns that these medications could affect eating restraint or body image in a harmful way and why psychological support might be key for their use. This conversation examines the limitations of current evidence and next steps for research at the intersection of metabolic medicines and eating disorders.
Click here to read the full article:https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(26)00256-7/fulltext
Who has been a guest on eClinicalMedicine in conversation with
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Sonja Aalbers
Jan Hontelez
Till Barnighausen
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