by Serotonin
The world is changing at an accelerating pace—Endgame is here to make sense of it. Hosted by Amanda Cassatt, founder of Serotonin, this podcast brings you conversations with the visionaries driving breakthrough technologies and shaping the future. Join Amanda as she unpacks the trends, innovations, and paradigm shifts defining our time. Where is this all going? Let’s figure it out together. Subscribe now on Apple Podcasts, Spotify, YouTube, and wherever you listen.
Language
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Publishing Since
3/12/2025
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July 29, 2026
<p>As chief cryptographer of Sui and Mysten Labs, Kostas Chalkias helped design a blockchain built on more than 100 published cryptography papers and an object-based architecture fast enough to let AI agents chain dozens of transactions into a single intent, without skipping the security research most "fast chains" leave out entirely.</p><p><br></p><p>In this episode of Endgame, Amanda Cassatt sits down with Kostas to break down why validators froze $163 million after the Cetus hack, why post-quantum migration can't wait for a crisis to force it, and why he thinks cryptographers now have exactly one place left to do their best work.</p><p>But the most unexpected part isn't the tech; it's the path. Chalkias was lecturing cryptography at universities in Dubai before spending three years building Facebook's ill-fated Libra project. He walked away from Meta because, in his words, it was too slow for how fast cryptography actually moves. Now he's chief cryptographer at one of the most talked-about L1s in the space.</p><p><br></p><p>Timestamp</p><p>0:00 – Is the quantum threat to Bitcoin and Ethereum real, or Sui's marketing wedge?</p><p>0:42 – Why every chain needs to start quantum migration now</p><p>2:32 – Why isn't a single top-40 blockchain quantum-safe yet?</p><p>7:52 – Why leave Facebook's Libra project to build another L1?</p><p>9:05 – Bitcoin, Ethereum, Solana already won so why build Sui?</p><p>21:06 – Why has Sui gone down more than once?</p><p>24:33 – The Cetus hack: why validators froze $163M</p><p>27:01 – What can only be built on Sui's object-based architecture?</p><p>30:14 – Is Sui's confidential-transactions push just Tornado Cash with extra steps?</p><p><br></p><p>Stay Connected</p><p> Amanda on X: https://x.com/amandacassatt </p><p> Serotonin on X: https://x.com/serotonin_hq </p><p> Spotify https://open.spotify.com/episode/45B9szUxVXEwfCDA6uRxwq?si=HT9XXqF9Q2CcM9hfLbmkVg </p><p><br></p><p>Endgame on Apple Podcasts</p><p> https://podcasts.apple.com/us/podcast/endgame-with-amanda-cassatt/id1801809440 </p><p><br></p><p>Follow Kostas Chalkias </p><p>https://www.linkedin.com/in/chalkiaskostas</p><p>https://x.com/kostascrypto?lang=en</p>
July 22, 2026
<p>Diogo Mónica co-founded Anchorage Digital, the first federally chartered crypto bank in the US, and now argues for a position most of Silicon Valley won't say out loud: America should be building closed AI, not open source.</p><p>In this episode of Endgame, Amanda Cassatt sits down with Diogo, Co-Founder of Anchorage Digital and General Partner at Haun Ventures, to break down why he thinks open-sourcing AI just hands China a free ride, why he calls AI "the ultimate weapon," and why he considers defending US AI intellectual property "perfectly legitimate."</p><p>They also discuss his board seat at Erebor, Palmer Luckey's new bank for crypto, AI, and defense companies; why stablecoins bridge crypto anarchism and financial regulation; and why he calls building in crypto an act of American patriotism.</p><p>Timestamp</p><p>0:56 – Kicking off with Katie Haun and Haun Ventures </p><p>2:13 – Reconciling his crypto-anarchist roots with his own philosophy </p><p>3:15 – Founding a regulated bank: Anchorage Digital </p><p>4:18 – Stablecoins: centralized control on decentralized rails </p><p>5:26 – Would a crypto anarchist say regulation just protects incumbents? </p><p>6:38 – Is building in crypto an act of American patriotism? </p><p>8:11 – Can crypto be "American-made" if it was born borderless? </p><p>13:25 – Introducing Palmer Luckey and the US-China AI/crypto landscape </p><p>14:21 – Is America on the right side of technology history?</p><p> 15:39 – Why he believes America should build closed AI, not open source</p><p> 16:31 – Does intellectual property even make sense in the AI age? </p><p>17:55 – Is the "China competition" narrative a political red herring? </p><p>18:18 – AI as "the ultimate weapon" and the end of mutually assured destruction</p><p> 19:46 – Turning the protectionism question back on China (Google, Gmail, Twitter) </p><p>20:21 – Building Erebor: Palmer Luckey's bank for crypto, AI, and defense </p><p>22:55 – Toward a left-wing and right-wing version of every business?</p><p> 24:14 – Crypto's real legacy: financial education for an entire generation</p><p><br></p><p>Stay Connected</p><p>● Amanda on X: https://x.com/amandacassatt </p><p>● Serotonin on X: https://x.com/serotonin_hq </p><p>● Spotify https://open.spotify.com/episode/45B9szUxVXEwfCDA6uRxwq?si=HT9XXqF9Q2CcM9hfLbmkVg </p><p><br></p><p>Endgame on Apple Podcasts https://podcasts.apple.com/us/podcast/endgame-with-amanda-cassatt/id1801809440 </p><p><br></p><p>Follow Diogo Monica</p><p>https://www.linkedin.com/in/diogomonica</p><p>https://x.com/diogomonica?lang=en</p><p><br></p><p> Don’t forget to subscribe!</p><p>#EndGame #AI #crypto #bitcoin #fintech</p>
July 15, 2026
<p>Robinhood is evolving far beyond commission-free trading.</p><p>In this episode of Endgame, Amanda Cassatt sits down with Johann Kerbrat, SVP & GM of Robinhood Crypto, for an in-depth conversation about how Robinhood is using blockchain, AI, and tokenization to reshape investing. Johann explains why Robinhood built its own Layer 2 on Ethereum, how tokenized stocks work in Europe, why Robinhood believes financial markets should operate 24/7, and how AI is changing the future of investing.</p><p>They also discuss crypto regulation, DeFi, prediction markets, Ethereum vs. Solana, Robinhood Wallet, self-custody, and Robinhood’s long-term vision for bringing traditional financial assets onchain. If you’re interested in crypto, fintech, investing, AI, or the future of financial markets, this conversation offers a rare look inside one of the world’s largest retail investing platforms.</p><p><br></p><p>In this episode:</p><p>• Why Robinhood built on Ethereum and Arbitrum</p><p>• Tokenized stocks explained (EU vs. US)</p><p>• The future of on-chain ownership</p><p>• Robinhood’s vision for 24/7 financial markets</p><p>• AI’s role inside Robinhood</p><p>• How AI agents could transform investing</p><p>• DeFi made simple</p><p>• Robinhood Wallet and self-custody</p><p>• Ethereum vs. Solana</p><p>• Prediction markets vs. gambling</p><p>• Robinhood’s acquisition of WonderFi</p><p>• The future of global investing</p><p><br></p><p>Timestamps: </p><p>00:00 Introduction</p><p>00:20 What Makes Robinhood Different</p><p>02:10 Crypto Fees and Accessibility</p><p>04:06 Crypto’s Role at Robinhood</p><p>05:06 Tokenized Stocks Explained</p><p>09:38 What Investors Actually Own</p><p>10:57 Putting Real Stocks Onchain</p><p>12:31 The Case for 24/7 Markets</p><p>15:48 Why Robinhood Chose Ethereum</p><p>18:12 KYC and Decentralization</p><p>20:12 Are L2s Good for Ethereum?</p><p>21:27 Ethereum vs. Solana</p><p>22:45 How Robinhood Uses AI</p><p>24:22 AI, DeFi and WonderFi</p><p>25:32 Trading vs. Gambling</p><p>29:39 What’s Next for Robinhood?</p><p><br></p><p>Stay Connected</p><p>Amanda on X: https://x.com/amandacassatt </p><p>Serotonin on X: https://x.com/serotonin_hq </p><p>https://open.spotify.com/episode/45B9szUxVXEwfCDA6uRxwq?si=HT9XXqF9Q2CcM9hfLbmkVg </p><p> </p><p>Endgame on Apple Podcasts: https://podcasts.apple.com/us/podcast/endgame-with-amanda-cassatt/id1801809440 </p><p><br></p><p>Follow Johann Kerbrat</p><p>https://x.com/JohannKerbrat?lang=en</p><p>https://www.linkedin.com/in/johann-kerbrat</p><p>#EndGame #Robinhood #Tokenization #DeFi #Web3</p>
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The world is changing at an accelerating pace—Endgame is here to make sense of it. Hosted by Amanda Cassatt, founder of Serotonin, this podcast brings you conversations with the visionaries driving breakthrough technologies and shaping the future. Join Amanda as she unpacks the trends, innovations, and paradigm shifts defining our time. Where is this all going? Let’s figure it out together.
Subscribe now on Apple Podcasts, Spotify, YouTube, and wherever you listen.
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