by 1PM
🌐 1PM.WIKI 🌐 🔍 🎲 Welcome to 1PM, in this series we will be breaking down complex medical topics into their First Principles. 😟 When the stress is on, and you’ve just been asked a tough question you don’t know the answer to, we feel you’ll be able to fall back on these principles to formulate a decent answer and reason your way out of trouble.
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Publishing Since
2/15/2022
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July 26, 2026
<p><u><strong>First Principles of Abnormal Uterine Bleeding (AUB)</strong></u></p><p>In this episode, we're going to break it all down from first principles. We'll walk through how to take a focused history without getting lost in the menstrual timeline, what investigations actually matter (and which ones don't), and how management changes depending on what's causing the bleeding.</p><p>As always, this isn't about memorising endless lists. It's about understanding the why behind the questions you ask and the tests you order, so the next time you're on ward rounds or in an OSCE, you'll know exactly where to start.</p><p>So grab your coffee, your notebook, or your favourite study snack, and let's dive into abnormal uterine bleeding—because periods might be monthly, but OSCEs can ask about them any day of the year!</p><p><br></p><p>Disclaimer: This episode was recorded on 8 May 2026. At the time of recording, the condition now known as <strong>Polyendocrine Metabolic Ovarian Syndrome (PMOS) </strong>was referred to as <strong>Polycystic Ovary Syndrome (PCOS)</strong>. Following the official nomenclature change announced on 12 May 2026, the term PMOS is now preferred. References to "PCOS" in this episode reflect the terminology that was in use at the time of recording.</p>
June 13, 2026
<p>First Principles of Abnormal Uterine Bleeding (AUB)</p><p>Think it's "just PMS"? Think again! In Part I of our AUB series, we dive into what counts as normal menstrual bleeding, when bleeding becomes abnormal, and the common causes behind it. Join us as we unpack the basics of Abnormal Uterine Bleeding and turn a confusing topic into something clear, practical, and surprisingly fascinating.</p><p><br></p><p>Disclaimer: This episode was recorded on 1 May 2026. At the time of recording, the condition now known as <strong>Polyendocrine Metabolic Ovarian Syndrome (PMOS) </strong>was referred to as <strong>Polycystic Ovary Syndrome (PCOS)</strong>. Following the official nomenclature change announced on 12 May 2026, the term PMOS is now preferred. References to "PCOS" in this episode reflect the terminology that was in use at the time of recording.</p><p><br></p>
November 8, 2025
<p>The First Principles of Seizures (Summary): Join us for the summary version of our seizures episode.</p><p><a href="https://1pm.notion.site/38-Seizures-2a5ef1d0b55f8050834ed4b5a292610b">1PM Notion: Seizures</a></p><p>=== Other Links ===</p><p>1PM Website</p><p>Check out our new website <a href="https://1pm.notion.site/4510c91c17314baf8f6b8e30b59159bb?v=e9a7d53846c842ba9b0b79836ef6020a">1pm.wiki</a> for the Notion document, free Anki flashcards, and podcast episodes.</p><p>Instagram: <a href="https://www.instagram.com/firstprinciplesofmedicine/%E2%81%A0%E2%81%A0%E2%81%A0%E2%81%A0%E2%81%A0%E2%81%A0%E2%81%A0%E2%81%A0%E2%81%A0%E2%81%A0%E2%81%A0%E2%81%A0%E2%81%A0%E2%81%A0">https://www.instagram.com/firstprinciplesofmedicine/</a></p><p><br></p><p>Recorded 27th of July, 2025. Hosts: Benjamin Earner, Saud Rana, Jasper Jackson. Produced by Benjamin Earner.</p><p><br></p><p>If you have any ideas or feedback, comment on this Notion document, or shoot us an email at hello@1pm.wiki</p><p>© First Principles of Medicine 2025</p>
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Dr Matthew Ghodsian
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🌐 1PM.WIKI 🌐
🔍 🎲 Welcome to 1PM, in this series we will be breaking down complex medical topics into their First Principles.
😟 When the stress is on, and you’ve just been asked a tough question you don’t know the answer to, we feel you’ll be able to fall back on these principles to formulate a decent answer and reason your way out of trouble.
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