This podcast is hosted by biotech entrepreneur Sushant Kumar, Founder & CEO of Genefitletics. Through this exclusive health podcast, he addresses the information asymmetry in the preventive health space. He is currently building Genefitletics, which is a direct-to-customer Biotech company- that studies & analyses activities of single & multicellular microorganisms living on & inside human body to provide precision health interventions in order to eradicate epidemic of chronic diseases, cancer & more.
Genefitletics
Claim This Podcastby Sushant Kumar
108 episodes
Updated Bi-weekly
Accepts GuestsHas SponsorsLocation 🇺🇸
41
Podcast Authority
BetaFairBased on show quality, social media presence, reviews, charts, and more
Quality51
Social91
YouTube0
Engagement30
Podcast Overview
This podcast is hosted by biotech entrepreneur Sushant Kumar, Founder & CEO of Genefitletics. Through this exclusive health podcast, he addresses the information asymmetry in the preventive health space. He is currently building Genefitletics, which is a direct-to-customer Biotech company- that studies & analyses activities of single & multicellular microorganisms living on & inside human body to provide precision health interventions in order to eradicate epidemic of chronic diseases, cancer & more.
Language
🇺🇲
Publishing Since
6/10/2020
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41
Podcast Authority
BetaFairBased on show quality, social media presence, reviews, charts, and more
Quality51
Social91
YouTube0
Engagement30
6
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13
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excellent
Episode Length
38 minutes
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needs improvement
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Every 18 days
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Recent Episodes
June 16, 2026
The Energetic Physics of Mitochondria- Why Breakdown Here Causes Cancer & Degeneration
<p>While we are too much focussed on decoding our genome, using wearables to track our health at plasma level & or leveraging DNA-Protein-drug pipeline to manage our post-symptomatic disease conditions, we have missed the key organelle that controls our biology- Mitochondria.Mitochondria is not just a powerhouse of cells as has been thought over decades. Even mitochondria, found in every cell except the red blood cells, is considered to be the motherboard of cells & is a distributed network. It has various receptors which allows it to sense environmental cues, process & integrate information & send signals to nucleus, driving epigenetic modifications & cytokine production that drive cellular adaptations & recalibrations.To understand the energetic processes of mitochondria, we have to understand the application of the laws of physics on human biological systems. Our body has a limited energy budget & is allocated among competing biochemical processes.Cellular stressors could lead to high energy resistance & disrupt the flow of electrons/increase in supply of electrons that could lead to flow back of electrons & production of reactive oxygen species. Mitochondria could also leak out its own DNA that enters the nucleus to communicate stress. This leads to production of cytokines & mitobiokines that drives this communication of stress to other cells as well as body- brain communication. These communication cascades lead to reallocation of energy from expensive growth, maintenance & repair to response to stressors- called as allostatic response, leading to new allostatic state. This persistence allostatic state leads to allostatic overload, systemic dysregulation, breakdown in communication network & onset of disease.From cancer perspective, we need to understand that it is not mutations but disruption in calcium circuits/ion channels & calcium overload that acts as electrostatic barrier to block the gap junction intercellular communication network, making dysfunctional cells detach from the cell collective & pursue its unicellular objectives. Interestingly the ion channels, whose movement drives & controls the biolelectric pattern, the voltage gradient of cells, resides in the mitochondrial inner & outer membrane & is controlled by mitochondrial functions. In effect mitochondria modulates these bioelectric patterns via controlling movement of ion channels, thereby impacting proliferation, differentiation, migration, and apoptosis of cells.In our today’s talk, we discussed how energetic processes of mitochondria drives cellular homeostasis & how breakdown in these processes can lead to organ & systemic dysfunction & onset of degenerative diseases & cancerKnow more at: www.genefitletics.com</p><p><br></p>
January 30, 2026
Are bloodworks reliable for measuring your health?
<p>The innovation in healthcare is still on the backseat with focus on existing primitive biomarkers which the healthcare practitioners have been tracking for decades.We still rely on routine blood biomarkers be it HDL, LDL, Hba1c, Homocysteine & more that just tells a macro level view & does not provide insights that could drive health promoting outcomes.Now we have seen a number of healthtech startups adding a wearable layer to these routine blood works & assume that marriage of these two( irrelevant) measures will help address health to the core?What are these companies even thinking ?If we go down & understand human evolution which dates back to 1.5 billion years ago, multicellularity defines how our cells operate collectively towards larger morphogenetic objectives & are bound by a social contract. In fact, it is ancient bacteria- mitochondria that controls this cell collective & drives cell to cell communication, behavior & decision making via transmitting signals using the bioelectric network of the cell collective.These mitochondria via its information processing system can process & integrate information & release biochemical signals that tell nucleus to turn on or off specific genes that codes for specific proteins that triggers cell to cell communication. This communication may tell the immune cell to grab all energy to address the toxin insults, make or disrupt hormone production, raise blood sugar, blood pressure & more.This clearly reflects that the focus should be understanding the interaction between environment, microbiome & mitochondria, reprogramming the bioelectric signalling that could drive big anatomical results to reinstate cellular homeostasis.Our founders Sushant & Sakshi deep dive into discussing why focussing on blood works + wearables is irrelevant & cannot help you transform your biology. </p><p><br></p><p>Know how Genefitletics is making an impact in helping you achieve the best of your health</p><p><br></p><p>www.genefitletics.com/orahyg</p><p><br></p><p><br></p><p><br></p>
January 2, 2026
How to personalise your protein intake?
<p>We Indians have got obsessed with protein based on a confusing but dubious marketing narrative- “India is a protein deficient nation”. This has led to launch of numerous startups launching protein supplement- Whey protein, plant based protein, protein bars, protein wafers & moreWe have seen a number of influencers promoting high consumption of protein but if protein deficiency is a reality, is high consumption the solution? How about how each of amino acid is metabolised right now .Let us decode this mystery todayWhat are symptoms of protein deficiency?- Fatigue, skin issues, low muscle mass & more. Are low or marginal income individuals who do not have financial liberty to purchase protein supplements, have protein deficiency? The fact is protein is an essential macromolecule & is required for vital cellular & metabolic processes but marketing as an alternative for every single chronic health condition is a blatant lie.Over the last few years, we have been focussed on personalising our food choices to regulate our blood sugar response but we have not bothered to ask this simple question- Why do not we personalise our amino acids? There are 9 essential amino acids that confer different host benefits or trigger production of signalling molecules & metabolites that could either lead to cellular resilience or cellular inflammation.Just a blanket recommendation of consuming some X gram/KG/day does not translate into biochemical interactions that deliver metabolic health & protein synthesis benefits. Most of the recommendations are based on population studies considering every individual as average healthy while our biology is unique & is neither average nor healthy.Therefore protein deficiency is not a standard deficiency & is a function of your unique biology & how your microbiome interacts with each amino acids.When you fall for these marketing narratives & consume protein in excess, without understanding how each of amino acid interacts with your biology or you lack stomach acid to break protein into constituent amino acids, your microbiome may ferment these amino acids into harmful metabolites that could trigger systemic inflammation. For instance, Imdizole propionate, a microbial byproduct of amino acid histamine leads to glucose intolerance, type 2 diabetes & even an early risk factor independent of cholesterol changes.If you have protein deficiency it is not a function of consumption but how each amino acid interacts with your biology including your microbiome. Personalising amino acids based on your cellular biochemistry is key to better protein synthesis, neurotransmitter production, skin health, metabolic health.Our data shows that 69% of our customers have protein fermentation levels as average with 87% found eggs in minimise list. We at Genefitletics measures your cellular biochemistry to determine how each of amino acid is metabolized & deliver personalised biotherapeutics interventions that promote benefits from amino acid metabolism.Know more here: www.genefitletics.com/orahyg#protein #proteinpowder #proteinshake #proteinsnack #protein #proteinpowder #proteinsnack #proteinshake #supplements #supplementfacts #supplementreview #supplement #wheyprotein #wheyisolate #whey #wheyproteinpowder #wheyconcentrate #arginine #bloating #constipation #constipationawareness #larginine #citrulline</p>
108 total episodes available
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Frequently asked questions
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- What is Genefitletics?
- How often does this podcast release new episodes?
This podcast updates bi-weekly.
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This podcast is available on 10 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.
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Yes, this podcast regularly features guests.
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