The GvHD Hub is an open-access online resource, dedicated to providing balanced, credible, and up-to-date medical education in GvHD. Our aim is to enhance knowledge in GvHD, through the multichannel dissemination of global advances related to their classification, diagnosis, treatment, and management.
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What are the key clinical considerations for the use of ECP in steroid-refractory GvHD?
The GvHD Hub spoke with Daniel Wolff, University Hospital Regensburg, Regensburg, DE. We asked, What are the key clinical considerations for the use of ECP in SR-GvHD? In this interview, Wolff discusses factors guiding the use of extracorporeal photopheresis in steroid-refractory graft-versus-host disease. Treatment decisions should account for patient- and disease-related factors, including cytopenias, risk of infection or malignant relapse, and organ involvement, alongside practical considerations, such as venous access, treatment frequency, and the commitment required for long-term therapy. Intended for healthcare professionals. This educational resource is independently supported by Therakos. All content is developed by SES in collaboration with an expert steering committee. Funders are allowed no influence.
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6 Oct 2026
What are the challenges involved in enrolling pediatric patients in cGvHD clinical trials?
The GvHD Hub spoke with Andrew Harris, Memorial Sloan Kettering Cancer Center, New York, US. We asked, What are the challenges involved in enrolling pediatric patients in cGvHD clinical trials?
During this interview, Harris discusses key barriers to enrolling pediatric patients with chronic graft-versus-host disease (cGvHD) in clinical trials, including the limited number of specialist centers with expertise in managing pediatric cGvHD and the resulting need for some children and their families to travel considerable distances to participating sites. He also highlights how the rarity of cGvHD in children may make it difficult to identify eligible patients for clinical trials.
Intended for healthcare professionals. This educational resource is independently supported by Sanofi. All content is developed by SES in collaboration with an expert steering committee. Funders are allowed no influence.
Hosted on Acast. See acast.com/privacy (https://acast.com/privacy) for more information.
6 Oct 2026
What are the key barriers to patient participation in cGvHD clinical trials?
The GvHD Hub spoke with Steven Pavletic, Bethesda, US. We asked, What are the key barriers to patient participation in cGvHD clinical trials?
During this interview, Pavletic discusses key factors that may impact patient participation in chronic graft-versus-host disease (cGvHD) clinical trials, including the practical and emotional demands associated with trial involvement, as well as concerns regarding treatment-emergent adverse events and potential long-term effects of investigational therapies. He highlights the importance of empowering patients and involving them in decisions about their care, with clear communication helping to ensure that patients are well informed and have realistic expectations about trial participation.
Intended for healthcare professionals. This educational resource is independently supported by Sanofi. All content is developed by SES in collaboration with an expert steering committee. Funders are allowed no influence.
Hosted on Acast. See acast.com/privacy (https://acast.com/privacy) for more information.
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Podcast Authority Score: 23 / 100
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