A podcast for the people building healthcare's data and AI future.
High Dimensional Health Data
Claim This Podcastby highdimensional
5.0(4 reviews)
5 episodes
Updated Daily
Accepts GuestsHas SponsorsLocation 🇺🇸
35
Podcast Authority
BetaPoorBased on show quality, social media presence, reviews, charts, and more
Quality11
Social0
YouTube66
Engagement81
Podcast Overview
A podcast for the people building healthcare's data and AI future.
Language
🇺🇲
Publishing Since
4/10/2025
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35
Podcast Authority
BetaPoorBased on show quality, social media presence, reviews, charts, and more
Quality11
Social0
YouTube66
Engagement81
8
Excellent Areas
0
Good Performance
11
Growth Opportunities
excellent
Episode Length
52 minutes
Performing excellently!
poor
Publishing Consistency
Every 35 days
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Recent Episodes
October 3, 2025
Reasoning LLMs in Medicine with David Sontag
<p>David Sontag, AI researcher and CEO of Layer Health, joins hosts Phil Ballentine and Aaron Neiderhiser to discuss how AI can meaningfully transform healthcare. From his formative years at Google and MIT to founding Layer Health, David shares what it takes to build AI that truly understands clinical data and improves care. We cover the evolution of machine learning, reasoning in large language models, why healthcare has lagged in AI adoption, and where the biggest opportunities lie today.TIMESTAMPS:(00:00) Introduction and guest background(01:12) Early interest in AI and machine learning(01:53) Academic journey and influences(03:27) Internship at Google and key experiences(06:41) Milestones in AI development(11:32) PhD research and medical applications(14:30) Transition to healthcare AI(27:49) Founding of Layer Health(36:01) Current focus and future prospects(46:23) Conclusion and contact information🔔 SubscribeFor deep dives and guest interviews about healthcare data, AI, and the future of health tech.🎙️ About High Dimensional Health Data (HD²) HD² is the podcast for people building healthcare's data and AI future. Hosted by Aaron and Phil, HD² explores the intersection of healthcare, data, and AI, and focuses on conversations with builders and practitioners.Hosts Phil Ballentine – Sr Director, Data Engineering at Atropos Health 🔗 LinkedInAaron Neiderhiser – Co-Founder and CEO at Tuva Health 🔗 LinkedInGuest David Sontag – CEO at Layer Health 🔗 LinkedIn📩 Interested in working together or coming on the podcast as a guest? Email us at hello@highdimensional.health<br /></p>
August 28, 2025
Alyssa Antonopoulos on LLMs, Oncology, and the Future of Evidence Generation
<p>In this episode, we chat with Alyssa Antonopoulos, a bioinformatician at Natera who spends her days wrangling some of the messiest data in healthcare. We get into the chaos of clinical abstraction, why large language models are exciting (but not magic), and how a single phrase like “last day of therapy” can derail an analysis. Alyssa walks us through Natera’s journey from prenatal testing to cancer monitoring and kidney disease, and we talk about what real-world evidence could look like when the data finally starts playing nice.TIMESTAMPS(0:00) Intro(1:59) Understanding Natera’s Flagship Test(3:34) Natera’s Expansion into Therapeutic Areas(5:09) Real-World Data and Monitoring Frequency(6:40) Data Integration and Abstraction Challenges(9:27) Leveraging Large Language Models for Data Extraction(11:30) Evaluating and Improving Data Accuracy(21:43) Flexible Data Structures for Analysis(23:07) Data Modeling and Oncology Challenges(23:40) Importance of Semantic Definitions(24:27) Data Dictionaries and Abstraction Logic(26:24) Oncology and Chronic Kidney Disease Analyses(27:35) Genomic Landscapes and ctDNA Dynamics(28:25) Kaplan–Meier Analyses in CKD(34:56) Future of Real-World Data and Evidence(38:55) Leading a Data Team: Advice and Insights(42:38) Closing Remarks and Future Plans🔗Links & Resources:Natera Inc: https://www.natera.com/🔔 Subscribe For deep dives and guest interviews about healthcare data, AI, and the future of health tech.🎙️ About High Dimensional Health Data (HD²) HD² is the podcast for people building healthcare's data and AI future. Hosted by Aaron and Phil, HD² explores the intersection of healthcare, data, and AI, and focuses on conversations with builders and practitioners.HostsPhil Ballentine – Sr Director, Data Engineering at Atropos Health🔗 https://www.linkedin.com/in/phil-ballentine/Aaron Neiderhiser – Co-Founder and CEO at Tuva Health🔗 https://www.linkedin.com/in/aaronneiderhiser/GuestsAlyssa Antonopoulo – Senior Director, Data and Informatics (RWD) at Natera 🔗https://www.linkedin.com/in/alyssa-antonopoulos/ Interested in working together or coming on the podcast as a guest? Email us at hello@highdimensional.health</p>
June 27, 2025
Mara Alexeev on Messy Clinical Data, the Limit of EHRs, and the Future of Clinical Informatics
Clinical informatician and pediatrician Mara Alexeev discusses the challenges of messy clinical data and the limitations of electronic health records, while hosts Phil Ballentine and Aaron Neiderhiser explore the future of clinical informatics in this interview.
5 total episodes available
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Mara Alexeev
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Frequently asked questions
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- What is High Dimensional Health Data?
- How often does this podcast release new episodes?
This podcast updates daily.
- Where can I listen to this podcast?
This podcast is available on 4 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.
- Does this podcast accept guests?
Yes, this podcast regularly features guests.
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