A podcast at the crossroads of microbiology, immunology, evolution, computational biology and more. Through informal interviews with researchers and students, I explore how biological organisms are "holobionts": super-organisms formed by a host and all of its communities of micro-organisms ( bacteria, viruses, fungi...)
Podcast Overview
A podcast at the crossroads of microbiology, immunology, evolution, computational biology and more. Through informal interviews with researchers and students, I explore how biological organisms are "holobionts": super-organisms formed by a host and all of its communities of micro-organisms ( bacteria, viruses, fungi...)
Language
🇺🇲
Publishing Since
5/2/2021
1 verified contact email on file for Holobiont
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Recent Episodes
November 13, 2022
#22 Can (and should) we patent DNA ? (Jorge L. Contreras)
<p><strong>Jorge L. Contreras</strong> is a Professor of Law at the University of Utah, specialising in <strong>Intellectual Property and Technology Law</strong>. He is the author of 150+ scholarly publications, alongside praised non-fiction books including “The Genome Defense: Inside the Epic Legal Battle to determine who owns your DNA” (2021). This book explores the <strong>AMP vs Myriad Case</strong>, which was sparked by patents litigations on the breast cancer gene <strong>BRCA</strong> for diagnostics, and historically determined that naturally occuring genes cannot be patented.</p> <p><strong>Timestamps</strong></p> <p>[01:00] Fundamental Principles of Patenting</p> <p>[08:30] Novelty and Utility in Patenting</p> <p>[10:40] BRCA and the AMP vs Myriad Case</p> <p>[17:00] Ethics of gene patenting </p> <p>[23:30] The case for gene patents in biotech</p> <p>[28:15] Alternative intellectual property than patents </p> <p>[33:00] Gene patents on pandemic pathogens</p> <p>[38:00] Patents in a globalised world</p> <p>[44:00] Future challenges in biotech patents </p> <p><strong>The Genome Defense Book Website</strong> : <a href="https://genomedefense.org/">https://genomedefense.org</a></p> <p>A thought about the genome as a public good, like a shared universal truth contained in all life forms, and faithfully entrusted from one generation to the next </p> <p>**Whoever has seen the universe, whoever has beheld the fiery designs of the universe, cannot think in terms of one man** (Borges, The God's Script (La escritura del Dios))</p> <p><br></p>
October 30, 2022
#21 The Tangled Story of H.pylori (Barry Marshall)
<p><strong>Barry Marshall</strong> is a Professor of Clinical Microbiology at the University of Western Australia. Alongside Robin Warren, he received the <strong>Nobel Prize in Physiology or Medicine</strong> in 2005 for first showing that <strong>Helicobacter pylori</strong><strong> </strong>bacteria, rather than acid, were the cause of <strong>stomach ulcers</strong>. For this, Marshall did a self-experiment where he ingested H.pylori and gave himself acute gastritis, establishing a first link between the infectious agent and the development of gastric disorders. </p> <p>We also embark on (a few) tangents: </p> <ul> <li>[00:00] The acid theory of ulcers</li> <li>[09:20] Curiosity-driven research</li> <li>[11:10] Self-experiment ingesting H.pylori</li> <li>[24:15] Non-invasive diagnostics</li> <li>[31:00] Peer-review </li> <li>[40:45] Reproducibility</li> <li>[46:15] Unanswered questions around H.pylori</li> <li>[50:35] Bacteria as vectors </li> <li>[57:45] Inflammation and cancer </li> <li>[1:05:00] The Microbiome Revolution</li> <li>[1:13:20] Charles Darwin</li> <li>[1:18:45] Book recommendations</li> <li>[1:21:10] Karry Mullis</li> </ul> <p><br></p> <p><br></p> <p><strong>Barry Marshall's blog</strong>: http://barryjmarshall.blogspot.com</p> <p><strong>Barry Marshall's Nobel Lecture (2005):</strong> https://www.nobelprize.org/prizes/medicine/2005/marshall/lecture/</p> <p><strong>Kary Mullis' Book</strong>: Dancing Naked in the Mind Field (1998)</p> <p><strong>Brother Surgeons: </strong>Brother Surgeons (1963) Garet Rogers</p> <p><br></p> <p><br></p> <p><br></p>
July 28, 2022
#20 Philosophy of Immunology and the Biological Self (Thomas Pradeu)
<p><strong>Thomas Pradeu</strong> is a CNRS Research Director in <strong>Philosophy of Science</strong>, leading a group at the <strong>ImmunoConcept</strong> called <strong>Conceptual Biology and Medicine</strong>. His group explores conceptual aspects spanning immunology, evolutionary biology, ageing and the microbiome. </p> <p>We discuss:</p> <ul> <li>What Philosophy of Immunology is </li> <li>How to assess the influence of an idea</li> <li>Misconceptions about the immune system</li> <li>The usefulness of the self/non-self framework</li> <li>Definitions of cancer in multicellular organisms</li> <li>How to integrate philosophy in science</li> </ul> <p>The ImmunoConcept lab page: https://immunoconcept.cnrs.fr</p> <p><br></p> <p><br></p> <p><br></p>
22 total episodes available
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