Technology is moving fast. Very fast. In each episode of I/O You an Explanation, we'll tackle a topic in technology and talk to an expert. We'll have a candid conversation about where the technology came from, its impact on us, and what makes it important. Whether it's completely new to you, or you're just hearing some perspective you hadn't thought of, by the end of the episode, you'll have a better understanding of the tech that shapes our jobs and our lives.
Discover how IT leaders balance AI governance, tokenomics, and business value. CHAPTERS: 00:00 - Introduction: What Does a CIO Really Do? 02:00 - The Before Times: Office Phones & Analog Tech in 1993 06:42 - The Three Core Buckets of a CIO’s Job 10:45 - Aligning Tech Strategy with Measurable Business Outcomes 13:18 - CIO vs. CTO: Understanding Key Leadership Differences 14:06 - How Generative AI Is Changing the CIO Role 16:54 - AI...
25 Sept 2026
Autonomous Agents Are Changing Enterprise Workflows
How do autonomous software agents transition from answering questions to completing real work for your company? Overview Host Dan Ciruli (VP and General Manager of Cloud Native at Nutanix) sits down with Leslie Lee (Chief Product Officer at Squid AI) to explore the evolution of autonomous agents in business environments. They discuss combining structured and unstructured data, automating complex tasks through backend execution, and maintaining strict security in enterprise settings. Discove...
25 Aug 2026
How Distributed Storage Disrupted the Enterprise
Can enterprise IT run resilient, cloud-like infrastructure on standard commodity hardware? In this episode of I/O You an Explanation, host Dan Ciruli (VP, GM Cloud Native) and Steve Carter (Director of Product Marketing) trace the origins of Nutanix AOS from Google File System principles to modern multi-cloud operations. Discover how hyperconverged architecture eliminated single points of failure in IT infrastructure and why Kubernetes is maturing for stateful applications. CHAPTERS ...
26 Jul 2026
What is an AI Gateway and Why Do Your LLM Workloads Need One?
What is an AI Gateway, and why are traditional API gateways no longer enough for modern generative AI applications? In this episode of I/O You an Explanation, host Dan Ciruli sits down with Ashwini Vasanth, Principal Product Manager, to demystify the critical role of AI Gateways in managing enterprise LLM workloads. What You’ll Learn: What is an AI Gateway? How AI gateways extend beyond legacy API gateways to handle token-based metering, streaming outputs, and vendor lock-in prevent...
28 Jun 2026
What Is Model Context Protocol (MCP) and How Does It Work?
The input: Too much tech jargon. The output: Clarity. On this episode of I/O You an Explanation, host Dan Ciruli (VP and General Manager of Cloud Native at Nutanix) sits down with Laura Jordana (Principal Technical Marketing Engineer) to unpack this open-source protocol. Subscribe to I/O You an Explanation for monthly enterprise tech insights without the fluff.
26 May 2026
What Edge Computing Actually Means
Technology moves fast, but some of the most important infrastructural shifts are happening way out at the absolute edge of the network. In this episode of I/O You an Explanation, host Dan Ciruli sits down with Lynn Comp, Head of Data Center Group Market Readiness at Intel, to unpack why edge computing has become the hottest topic in modern architecture. From the streaming platforms caching your favorite holiday movies to the high-stakes world of real-time sports analytics, edge computing is q...
23 Apr 2026
The Evolution of Open Source with Kelsey Hightower
What does it take to turn a tech trend into a global standard? In this episode of I/O You an Explanation, recorded live at Nutanix .NEXT, host Dan Ciruli sits down with the "Explainer-in-Chief," Kelsey Hightower, to discuss the intersection of open-source legacy and the next frontier of automation. Kelsey bridges the gap between "The Before Times"—the grit of 80s gaming and the birth of Linux—and today’s rapid shift toward Agentic AI. He shares a masterclass in tech adoption, using a brilli...
24 Mar 2026
From Floppy Disks to Ambient Mesh: The Evolution of Service Communication with Louis Ryan
How did we go from manual 15-disk Windows installs to the seamless automation of modern cloud native environments? In this inaugural episode of I/O An Explanation, host Dan Ciruli sits down with industry legend Louis Ryan (CTO of Solo.io, co-founder of Istio, and co-inventor of gRPC) to unpack the past, present, and future of how services talk to one another. We dive into the foundational technologies that revolutionized modern software communication. Whether you are building internal microse...
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