This is a podcast that will help you navigate the complexities of dementia. It’s presented by two friends who come at the subject from two very different perspectives.
Professor Julie Williams has spent most of her working life trying to understand Alzheimer's disease and other forms of dementia. Meanwhile, Justine Pickering understands the colossal human cost all too well. She lost her mum to a rare form of young-onset dementia before founding a unique respite project for families coping with the emotional toll of the disease.
In Two Minds brings you the highs and lows of the shared experiences of dementia. We’ll hear inspiring special guests and all about current research and future treatments.
Together, we’ll explore the challenges of coping with this disease and how to live well following diagnosis.
In Conversation with Ruth Jones Part 2: Annie’s Legacy
In part 2 of the conversation with her friend Ruth Jones, Justine speaks with raw honesty about the heartbreak of slowly losing her mum, the realities of caring and the overwhelming guilt that so often follows. She reflects on the moments she wishes she could relive, the memories she clings to, and the pain of a Christmas Eve goodbye.
Driven by love and necessity, Justine created a respite project that transformed the lives of families living with dementia - a beautiful, dignified space where joy, music, kindness, and humanity come first, and where carers are finally given permission to rest.
This episode is about more than loss. It’s about making moments matter. It’s about finding light in the darkest places and about the profound impact one woman’s life can have long after she’s gone.
If you have any questions for Justine and Prof Julie, email us hello@twomindspodcast.co.uk.
For further help and advice, please visit
https://www.alzheimers.org.uk (https://www.alzheimers.org.uk/)
27 Jan 2026
In Conversation with Ruth Jones Part 1: When a Mother Needs Her Daughter
The one and only Ruth Jones joins the podcast for the next two weeks as co-host of In Two Minds. As Julie takes a little break, Justine shares with Ruth the story she never thought she could tell — the story of her mum, Annie, and their family’s journey through young-onset dementia.
Justine reflects on who Annie was before the diagnosis: a glamorous, funny, fiercely loving woman — a young mum and a devoted grandmother. Together, they explore the slow, bewildering onset of dementia, the thousand small moments that didn’t make sense at the time, and the heartbreak of watching independence, dignity, and language gradually slip away.
This episode speaks honestly about the realities of caring: the humiliation dementia can bring, the exhaustion of “orchestrated fun,” and the painful question of who normality is really for.
A tribute to Annie, and to all families living with dementia, this episode is about love in its rawest form — and why better understanding, support, and respite matter so deeply.
If you have any questions for Justine and Prof Julie, email us hello@twomindspodcast.co.uk.
For further help and advice, please visit
https://www.alzheimers.org.uk (https://www.alzheimers.org.uk/)
20 Jan 2026
Decoding Dementia: Dr. Emma Mead on the Future of Alzheimer’s Therapies
Dr. Emma Mead, Chief Scientific Officer, discusses the innovative science behind Alzheimer's and neurodegenerative diseases, highlighting microglia's potential in preventing dementia and the future of personalized treatments in this interview.
Who has been a guest on In Two Minds
Names identified in recent episode analyses. Showing up to five guests.
Dr Emma Mead
Tess Thomas
Rebecca Evans CBE
Jen
Caleb Webber
Podcast Authority Score: 32 / 100
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