
Inside Matters
Claim This Podcastby Dr James McIlroy
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Podcast Overview
<p>The gut health show – conversations with the most forward-thinking minds in health, fitness, science, nutrition and business. In-depth discussions about how our gut microbiome impacts our health, well-being, mood and more.<br /><br />Inside Matters was conceived by microbiome expert Dr James McIlroy as a platform to raise awareness of the importance of the gut microbiome. Our aim is to inspire and educate listeners around the world about the importance of gut health, equipping them with the knowledge they need to transform their lives for the better.</p> <p>Produced by the <a href="https://www.podcaststudioglasgow.com/" target="_blank" rel="noreferrer noopener">Podcast Studio Glasgow</a>.</p>
Language
🇺🇲
Publishing Since
9/12/2022
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Recent Episodes

July 23, 2026
Why We Eat: The Science of Appetite, Nutrition and Weight - Prof Alexandra Johnstone
Host Dr James McIlroy interviews Professor Alexandra Johnstone about the science of appetite, nutrition, and weight, revealing how our bodies, habits, and environments shape eating patterns.

April 2, 2026
The Importance of the Reproductive Tract Microbiome: Insights from David MacIntyre
Dr. James McIlroy interviews Professor David MacIntyre about the surprising low-diversity reproductive tract microbiome and its impact on pregnancy health.

December 4, 2025
Gut Health, Celiac Disease & the Future of Microbiome Medicine — With Dr Debra Silberg
Dr Debra Silberg joins Inside Matters for a deep, wide-ranging conversation on gut health, drug development, and the future of microbiome therapeutics. Dr Silberg is the Chief Scientific Officer at Beyond Celiac, a former global clinical leader at Shire/Takeda and AstraZeneca, and one of the most respected figures in GI medicine and microbiome science. In this episode, we explore:• How she moved from basic science to medicine to pharma leadership• Why the GI field needed so much research — and how it transformed• The real science behind ulcers, H. pylori, and the Barry Marshall story• What she teaches in her popular “Understanding Your Gut” course• Prebiotics vs probiotics — what actually matters• The truth about gluten, celiac disease, gluten sensitivity and rising incidence• The microbiome’s role in inflammation, autoimmune disease, mental health & IBS• Whether microbiome drug development is finally turning a corner• Why the gut–brain axis may be the most exciting frontier in medicine Dr Silberg also shares insights from her work with Finch Therapeutics, her role at Beyond Celiac, and her experience advising the team at Biotics. If you’re interested in gut science, the microbiome, diet, or how modern medicines are built from the ground up, you’ll get a huge amount from this conversation. Be well, trust your gut — and thanks for listening. 00:00 Introduction to Dr Debra Silberg 00:54 Dr Silberg's Career Journey 02:26 Insights on Gut Health and Microbiome 04:05 Understanding GI Diseases and Treatments 07:41 The Role of Diet in Gut Health 15:59 Celiac Disease and Gluten Sensitivity 25:04 Exploring the Microbiome 27:43 Exploring Therapeutic Approaches to the Microbiota 31:36 Challenges in Microbiome Drug Development 34:22 The Gut-Brain Connection and Mental Health 39:13 Transitioning from Academia to Pharma 41:45 Insights into Drug Development and Success Stories 44:55 The Long Journey of Drug Development 52:01 The Role of AI in FDA Reviews 55:04 Quick Fire Round: Future of Microbiome Research You must not rely on the information in this video as an alternative to medical advice from your doctor or other professional healthcare provider. If you have any specific questions about any medical matter you should consult your doctor or other professional healthcare provider. If you think you may be suffering from any medical condition you should seek immediate medical attention. You should never delay seeking medical advice, disregard medical advice, or discontinue medical treatment because of the information in this video.
71 total episodes available with 26 transcripts
Recent guests on Inside Matters
Guests from recent episodes — sign up to see every guest that has ever appeared on this show.
Alexandra Johnstone
Guest
Dr Ran Blekhman
Guest
Dr Johan van Hylckama Vlieg
Guest
Dr Chris Damman
Guest
Professor Yan Yiannakou
Guest
Cory Greenberg
Guest
Dr James McIlroy
Guest
Dr Joël Doré
Guest
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Frequently asked questions
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- What is Inside Matters?
<p>The gut health show – conversations with the most forward-thinking minds in health, fitness, science, nutrition and business. In-depth discussions about how our gut microbiome impacts our health, well-being, mood and more.<br /><br />Inside Matters was conceived by microbiome expert Dr James McIlroy as a platform to raise awareness of the importance of the gut microbiome. Our aim is to inspire and educate listeners around the world about the importance of gut health, equipping them with the knowledge they need to transform their lives for the better.</p> <p>Produced by the <a href="https://www.podcaststudioglasgow.com/" target="_blank" rel="noreferrer noopener">Podcast Studio Glasgow</a>.</p> - How often does this podcast release new episodes?
This podcast updates bi-weekly.
- Where can I listen to this podcast?
This podcast is available on 10 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.
- Does this podcast accept guests?
Yes, this podcast regularly features guests.
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