Investigating HLH, brought to you by Sobi Inc., is a podcast that takes a deep dive into the complex world of hemophagocytic lymphohistiocytosis, or HLH. As a rare and fatal disease that was once considered incurable, HLH presents with a range of severe signs and symptoms that make diagnosis difficult. Join us as we discuss insights about HLH from all angles with various experts in the field of hematology-oncology who have helped to advance the understanding and treatment of this devastating disease. When treating patients with HLH, knowledge is power—because knowing what to look for can save lives.

Investigating HLH
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Podcast Overview
Investigating HLH, brought to you by Sobi Inc., is a podcast that takes a deep dive into the complex world of hemophagocytic lymphohistiocytosis, or HLH. As a rare and fatal disease that was once considered incurable, HLH presents with a range of severe signs and symptoms that make diagnosis difficult. Join us as we discuss insights about HLH from all angles with various experts in the field of hematology-oncology who have helped to advance the understanding and treatment of this devastating disease. When treating patients with HLH, knowledge is power—because knowing what to look for can save lives.
Language
🇺🇲
Publishing Since
11/14/2023
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Recent Episodes

September 23, 2025
What is MAS?
Adam Narloch speaks with Dr. Daniella Schwartz and Dr. Randy Cron about recognizing and managing MAS, a rare subtype of HLH in rheumatic diseases.

February 25, 2025
Monitoring Treatment Response
Kari Magee speaks with Dr Bethany Verkamp to discuss her recent research on evaluating treatment response to etoposide-based treatment in patients with hemophagocytic lymphohistiocytosis (HLH).

June 27, 2024
A Treatment Option
<p>Adam Narloch speaks with Dr Michael Jordan to talk about his HLH research and a pivotal trial in HLH. Dr Jordan is a pediatric hematologist-oncologist at Cincinnati Children’s Hospital Medical Center and a professor in the Department of Pediatrics at the University of Cincinnati. Hear from Dr Jordan about his work exploring the pathology of HLH using mouse models, as well as the background, methods, and results from the Gamifant pivotal trial.</p><p>Indication</p><p>Gamifant is an interferon gamma (IFNγ)–blocking antibody indicated for the treatment of adult and pediatric (newborn and older) patients with primary hemophagocytic lymphohistiocytosis (HLH) with refractory, recurrent, or progressive disease or intolerance with conventional HLH therapy.</p><p>Important Safety Information</p><p>Infections</p><p>Before initiating Gamifant, patients should be evaluated for infection, including latent tuberculosis (TB). Prophylaxis for TB should be administered to patients who are at risk for TB or known to have a positive purified protein derivative (PPD) test result or positive IFNγ release assay.</p><p>Please see additional Important Safety Information and the full Prescribing Information for Gamifant at Gamifant.com.</p> <p><p>©2023 Sobi, Inc. All rights reserved. NP-32204 12/23 </p></p>
7 total episodes available
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Frequently asked questions
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- What is Investigating HLH?
- How often does this podcast release new episodes?
This podcast updates bi-weekly.
- Where can I listen to this podcast?
This podcast is available on 8 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.
- Does this podcast accept guests?
No, this podcast does not typically feature guests.
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