35 Episodes
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2021 First episode About 科普上層樓 惡補科普知識讓教授對你刮目相看
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美國加州大學博士以甜美嗓音提供你豐富的專業科普知識
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難易度:
國小程度 *
高中程度 ***
博士程度 *****
#科普 #科普上層樓 #科學 #Science #Science-up #Pharma #科普Podcast
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Publisher 科普上層樓
Category health & fitness · science · science
Language zh
Explicit No
First episode 5 Apr 2021
Latest episode 7 Sept 2025 Latest episodes 35 episodes in the feed.
7 Sept 2025
2025年 美國前10大昂貴藥物 難易度:****
有多貴???
為什麼這麼貴???
在治療什麼疾病
一次告訴你
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6 Feb 2024
癌症會劫持神經系統來生長和擴散?!!! 難易度: **
介紹新一波的研究正在揭示癌症和神經元之間的關係,並尋找可以阻止他們之間交流的方法。
#propranolol # calcitonin gene-related peptide, CGRP
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31 Jan 2024
治療COVID-19的主流抗病毒藥物 難易度: ****
介紹:
輝瑞新冠口服藥Paxlovid (nirmatrelvir/ ritonavir)
鹽野義新冠特效藥 Xocova (ensitrelvir)
先諾欣XIANNUOXIN (simnotrelvir/ ritonavir)
#3C-like protease #3CL protease #Pfizer #Shionogi #Simcere #Molnupiravir #Lagevrio
Paxlovid:
Owen, D. R. et al. An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19. Science (2021); 374: 1586–1593.
N Engl J Med. (2022); 14, 386(15):1397-1408. doi: 10.1056/NEJMoa2118542. Epub 2022 Feb 16.
Xocova:
Tyndall, J. D. A. S-217622, a 3CL protease inhibitor and clinical candidate for SARS-CoV-2. J. Med. Chem. (2022); 65: 6496–6498.
Antimicrob Agents Chemother. (2022);18, 66(10): e0069722. doi: 10.1128/aac.00697-22. Epub 2022 Sep 13.
XIANNUOXIN:
Jiang, X., Su, H., Shang, W. et al. Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir. Nat Commun (2023); 14: 6463. https://doi.org/10.1038/s41467-023-42102-y (https://doi.org/10.1038/s41467-023-42102-y)
Oral Simnotrelvir for Adult Patients with Mild-to-Moderate Covid-19 N Engl J Med (2024); 390: 230-241. DOI: 10.1056/NEJMoa2301425
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