Killer Chemistry is a true crime podcast hosted by investigative journalist Callie Lyons, uncovering the hidden dangers of environmental toxins. Explore toxic exposures rooted in military science that continue to affect millions. This gripping series reveals a silent killer’s impact on generations and the coverups that kept the truth buried, blending true crime with scientific investigation.
Smoke from an industrial fire forces a scary question into the open: what are we breathing right now? When containment fails, chemistry stops being a behind-the-scenes industrial process and becomes a community problem, fast. And in the first hours, the most accurate answer to “Is it dangerous?” is often the one people hate hearing most: we don’t know yet. I break down why that uncertainty is normal in environmental disasters and why it’s also when exposure risk can be highest. Fire crews ha...
26 Jun 2026
Ep. 7 - The Hellbender's Warning
Something ancient is vanishing from Appalachian streams, and the most unsettling part is how quietly it happens. We start under a flat rock in water cold enough to numb your fingers, where the hellbender salamander survives by breathing through its skin. That single fact turns it into a perfect early-warning system: every molecule in the current becomes personal, every storm can rewrite the chemistry of its world, and the first signs of trouble show up on its body before they show up in our h...
1 May 2026
Ep. 6 - Encountering the Unexplained
A man drives home on a cold November night in 1966, and the road in front of him stops feeling like the world he knows. Along Interstate 77 near Parkersburg, West Virginia, Woodrow Derenberger reports a craft close enough to halt traffic and a stranger with a fixed smile who “speaks” without moving his mouth. Minutes later it’s gone, but the details stick, especially that smile. Ten days after, downriver near Point Pleasant and the abandoned TNT area, another report lands in the dark: someth...
16 Apr 2026
Ep. 5 - The Shadow in the Woods
Something moves at the edge of the headlights near Point Pleasant, West Virginia, and the witnesses can’t find words that fit. A huge shape. Red reflective eyes. The feeling of being watched. The story gets a name, The Mothman, and after the Silver Bridge collapses into the Ohio River, the legend locks into place as a “warning.” But I can’t stop thinking about a more unsettling possibility: what if the creature is a symptom of a landscape that was chemically changed long before anyone could m...
8 Apr 2026
Ep. 4 - The Stranger on the Porch
We trace how Appalachian storytelling can carry a warning that science later proves, then follow the C8 contamination story as it moves across the Ohio River like a threat that never needed permission. We walk through how a rural water manager fought for a single number the system could not ignore, and why making results public changed what happened next. • Appalachian communication as layered truth and shared burden • The snake parable as a model for predictable harm and mispla...
31 Mar 2026
Ep. 3 - A Flood of Discovery Reveals the Haint in the Water
Something in Appalachia’s storytelling cuts closer to science than most people expect: the idea that certain things attach themselves, linger, and reshape your life even when you can’t see them. We use that lens to follow a real contaminant that behaves exactly that way, a synthetic forever chemical tied to Teflon production that doesn’t break down in the environment or move quickly through the human body. If you’ve heard “PFAS” or “PFOA” and wondered why communities describe it like a haunti...
24 Mar 2026
Ep. 2 - The Invisible Crime Scene
When most people picture a crime scene, they imagine yellow police tape and obvious danger. But environmental contamination rarely announces itself, and that’s the chilling frame for this true crime science story from Washington Bottom, West Virginia. The Ohio River Valley is steeped in folklore, cryptids, UFOs, alien sightings, and Appalachian rules for surviving the dark, yet the real threat here isn’t a cryptid. It’s industrial pollution that seeps into creeks and wells and into bodi...
23 Mar 2026
Ep. 1 - The Bomb's Secret Ingredient
A new podcast, Killer Chemistry, explores how military science developed during the Manhattan Project became part of the biology of nearly every living thing on Earth. Hosted by award-winning investigative journalist and author Callie Lyons, the series brings together scientific context, legal history, and lived experience to examine the origins and global presence of what are commonly referred to as “forever chemicals.” Killer Chemistry is a true crime science podcast, presenting a complex a...
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