KYSCO Oncology Voices, a podcast from the Kentucky Society of Clinical Oncology (KYSCO), delivers the latest in oncology care and advocacy efforts to the state's cancer care providers. The series provides up-to-date guidance on patient care and practice management, covering everything from clinical research to legislative advocacy.
With a focus on individualizing patient care and understanding tumor biology, this episode explores the extraordinary transformation of prostate cancer management for patients across Kentucky. Host Dr. Shreyas Kalantri from the University of Cincinnati speaks with oncologist Dr. Chandler Park from the Norton Cancer Institute to discuss the shift from standard androgen deprivation therapy (ADT) to modern doublet and triplet therapies for metastatic hormone-sensitive prostate cancer.
Host: Dr. Shreyas Kalantri, University of Cincinnati
Guest: Dr. Chandler Park, Oncologist, Norton Cancer Institute
The Kentucky Society of Clinical Oncology (KYSCO) (https://www.kysco-oncology.org/)
Email: blawrence@kysco-oncology.org
14 Sept 2026
Breast Cancer Updates in Kentucky Part 3: Metastatic HER2+, TNBC ADCs + Targeted Advances
In the concluding episode of our breast cancer series, host Dr. Matthew Kurian (St. Elizabeth
Young Family Cancer Center) reunites with Dr. Laila Agrawal (Norton Cancer Institute) and Dr.
Brian Dong (University of Louisville Health, Brown Cancer Center) to navigate major metastatic
trial updates and their real-world clinical implications across Kentucky. The panel compares
first-line HER2-positive metastatic strategies from the HER2CLIMB-05 and DESTINY-Breast09
studies, debating the quality-of-life trade-offs between indefinite antibody-drug conjugate (ADC)
therapy and non-chemotherapy maintenance regimens while highlighting key depth-of-response
data presented at ASCO 2026.
Host: Dr. Matthew Kurian, St. Elizabeth Young Family Cancer Center
Guests:
Dr. Laila Agrawal, Medical Oncologist, Norton Cancer Institute
Dr. Brian Dong, Breast Oncologist, University of Louisville Health, Brown Cancer Center
The Kentucky Society of Clinical Oncology (KYSCO) (https://www.kysco-oncology.org/)
Email: blawrence@kysco-oncology.org
8 Sept 2026
Breast Cancer Updates in Kentucky Part 2: Advances in HR-Positive Care
Focusing on hormone receptor-positive, HER2-negative (HR+/HER2-) early breast cancer, this episode explores landmark trial updates in genomic risk stratification and novel endocrine therapies, alongside their real-world clinical application for patients across Kentucky. Host Dr. Matthew Curran (St. Elizabeth Young Family Cancer Center) reunites with medical oncologists Dr. Laila Agarwal (Norton Cancer Institute) and Dr. Brian Dong (University of Louisville Health, Brown Cancer Center) to evaluate several trials.
Host: Dr. Matthew Curran, St. Elizabeth Young Family Cancer Center
Guests:
Dr. Laila Agarwal, Medical Oncologist, Norton Cancer Institute
Dr. Brian Dong, Breast Oncologist, University of Louisville Health, Brown Cancer Center
The Kentucky Society of Clinical Oncology (KYSCO) (https://www.kysco-oncology.org/)
Email: blawrence@accc-cancer.org
31 Aug 2026
Breast Cancer Study Breakthroughs and KY Real World Application Part 1: HER2-Positive
Evaluating practice-changing clinical trials, this episode examines recent breakthroughs in HER2-positive breast cancer management and their real-world application for patients across Kentucky. Host Dr. Matthew Curran (St. Elizabeth Young Family Cancer Center) is joined by medical oncologists Dr. Laila Agarwal (Norton Cancer Institute) and Dr. Brian Dong (University of Louisville) to analyze landmark studies, including DESTINY-Breast05, DESTINY-Breast11, and the Phase 3 NeoHealer trial. The panel discusses the integration of antibody-drug conjugates (ADCs) like T-DXd in both post-neoadjuvant residual disease and upfront settings, balancing impressive pathologic complete response (pCR) rates against toxicities such as interstitial lung disease (ILD), 14-cycle treatment burdens, and travel considerations for rural Commonwealth residents.
Host: Dr. Matthew Curran, St. Elizabeth Young Family Cancer Center
Guests:
Dr. Laila Agarwal, Medical Oncologist, Norton Cancer Institute
Dr. Brian Dong, Breast Oncologist, University of Louisville Health, Brown Cancer Center
The Kentucky Society of Clinical Oncology (KYSCO) (https://www.kysco-oncology.org/)
Email: blawrence@accc-cancer.org
This episode walks through the patient journey and clinical management of Autologous Stem Cell Transplantation (ASCT) for multiple myeloma, with an emphasis on multidisciplinary coordination and community practice collaboration.
Host Dr. Rafeh Safdar draws from his clinical experience on the Bone Marrow Transplant service at UK Chandler Hospital alongside Dr. Zena Chahine to break down candidate evaluation, stem cell mobilization, high-dose conditioning and Day 0 reinfusion. The discussion offers practical insights for community oncologists on dynamic candidate eligibility, patient preparation, and streamlining referrals to academic transplant centers.
Host: Dr. Rafeh Safdar, Hematology/Oncology Fellow, University of Kentucky
Guest: Dr. Zena Chahine, Hematologist & Multiple Myeloma Specialist, UK Markey Cancer Center
The Kentucky Society of Clinical Oncology (KYSCO) (https://www.kysco-oncology.org/)
Email: blawrence@accc-cancer.org
24 Aug 2026
Multiple Myeloma Updates Part 1: Diagnosis & Frontline Management
With a focus on early intervention and modern risk stratification, this episode explores how recent advancements in plasma cell dyscrasia management are transforming care for multiple myeloma patients across Kentucky.
Host Dr. Rafeh Safdar, Hematology/Oncology Fellow at the University of Kentucky, speaks with myeloma specialist Dr. Zena Chahine from the UK Markey Cancer Center to discuss the evolution from classic CRAB to modern SLIM CRAB criteria, diagnostic workups, cytogenetics, and frontline quadruplet induction regimens.
The conversation highlights real-world clinical implications, supportive bone-directed care, and the importance of personalized, long-term disease management in the Commonwealth.
Host: Dr. Rafeh Safdar, Hematology/Oncology Fellow, University of Kentucky
Guest: Dr. Zena Chahine, Hematologist & Multiple Myeloma Specialist, UK Markey Cancer Center
The Kentucky Society of Clinical Oncology (KYSCO) (https://www.kysco-oncology.org/)
Email: blawrence@accc-cancer.org
2 Feb 2026
Liver-Directed Malignancies in Kentucky
With a focus on improving access and modernizing surgical techniques, this episode covers how the hepatic artery infusion (HAI) pump is transforming the landscape for patients with liver-directed malignancies in Kentucky.
Host Dr. Zach Pulliam, Medical Oncology Fellow at University of Louisville, speaks with expert Dr. Michael Cavnar from the University of Kentucky Markey Cancer Center to discuss the history, clinical benefits, and new accessibility trials for HAI pump therapy.
The conversation focuses on the logistics of rural cancer care, survival benefits for colorectal liver metastases and cholangiocarcinoma, and the future of home-based chemotherapy infusion.
Host: Zach Pulliam, MD,
Guest: Michael Cavnar, MD
The Kentucky Society of Clinical Oncology (KYSCO) (https://www.kysco-oncology.org/)
blawrence@kysco-oncology.org
29 Jan 2026
Latest on Hepatic Arterial Infusion Pump Therapy
This episode explores the latest advancements in hepatic arterial infusion (HAI) pump therapy and its impact on cancer care in Kentucky. Surgical Oncologist Brent Xia, MD of the St. Elizabeth Cancer Center, discusses the multidisciplinary effort required to implement this technology and its role in providing targeted, high-dose chemotherapy for liver-directed
The conversation highlights the survival benefits of regional therapy, the importance of multidisciplinary tumor boards, and new ways to reduce financial toxicity for patients.
Host: Andrew Hearn, MD, Hematology & Oncology Fellow, University of Louisville
Guest: Brent Xia MD Surgical Oncologist, St. Elizabeth Healthcare / The Yung Family Cancer Center
The Kentucky Society of Clinical Oncology (KYSCO) (https://www.kysco-oncology.org/)
https://www.interaoncology.com/patients-caregivers/find-an-hai-center
blawrence@kysco-oncology.org
19 Sept 2025
Focus on Small Cell Lung Cancer Treatment in Kentucky
With a focus on improving access and managing toxicity, this episode covers how new therapies are transforming the landscape for small cell lung cancer patients across the state.
Host Dr. Shreyas Kalantri, Hematology and Oncology Chief Fellow at University of Louisville, speaks with experts Dr. Goetz Kloecker and Dr. Firas Badin to discuss groundbreaking trials and treatment advances for small cell lung cancer like the IMforte and DeLLphi-304 studies. The conversation focuses on real-world implications, survival benefits, and the future of cancer care in Kentucky.
Host: Dr. Shreyas Kalantri
Guest: Dr. Goetz Kloecker
Guest: Dr. Firas Badin
The Kentucky Society of Clinical Oncology (KYSCO) (https://kysco.accc-cancer.org/)
Email: blawrence@accc-cancer.org
29 Aug 2025
Transforming Lung Cancer Care in Kentucky
In the latest episode of KYSCO Oncology Voices, host Dr. Shreyas Kalantri, Hematology and Oncology Chief Fellow at University of Louisville, shares updates on recent advances in non-small cell lung cancer (NSCLC) with renowned experts Dr. Goetz Kloecker and Dr. Firas Badin.
They cover landmark trials such as CheckMate 816 (neoadjuvant immunotherapy) and NeoADAURA (neoadjuvant targeted therapy for EGFR-mutant NSCLC), discussing their implications on practice and the multidisciplinary approach to lung cancer care in Kentucky. With Kentucky having one of the highest lung cancer incidence rates, this episode focuses on how recent trial findings can shape patient outcomes in our state.
Tune in to explore how cutting-edge research is being translated into real-world clinical practices.
Host: Dr. Shreyas Kalantri
Guest: Dr. Goetz Kloecker
Guest: Dr. Firas Badin
The Kentucky Society of Clinical Oncology (KYSCO) (https://kysco.accc-cancer.org/)
Email: blawrence@accc-cancer.org
8 Jul 2025
Key Breast Cancer Updates from Recent SERENA-6 and ASCENT-04 Trials
Are you up-to-date with the latest breast cancer advances? In the latest episode of KYSCO Oncology Voices, host Dr. Matthew Kurian discusses key breast cancer updates from ASCO 2025 with guest experts Dr. Brian Dong and Dr. Ruta Arays.
They explore trial results, including SERENA-6 and ASCENT-04, and their potential implications for treatment decisions in Kentucky. Tune in to understand how these updates might impact both academic and community settings, focusing on the specific challenges faced in Kentucky.
Host: Dr. Matt Kurian
Guest: Dr. Ruta Arays
Guest: Dr. Brian Dong
The Kentucky Society of Clinical Oncology (KYSCO) (https://kysco.accc-cancer.org/)
Email: blawrence@accc-cancer.org
2 Jun 2025
Prostate Cancer Care in Kentucky
Kentucky is working to reduce disparities and improve early cancer detection. In the inaugural episode of the Kentucky Society of Clinical Oncology (KYSCO) Podcast, host Dr. Matt Kurian talks with experts Mollie Beck, Oncology Pharmacist, and Jordan Brady, Coordinator of Clinical Genetics, about everything from local statistics to genetic screenings and treatments. Listen to learn about the importance of early detection, legislative changes, and the benefits of both germline and somatic testing.
Host: Matthew Kurian, MD (https://www.linkedin.com/in/matthew-kurian-md-097aa1216/)
Guest: Mollie Beck, PharmD, BCOP
Guest: Jordan Brady, MS, CGC (https://www.linkedin.com/in/jordan-brady-ms-cgc-846380b2/)
The Kentucky Society of Clinical Oncology (KYSCO) (https://kysco.accc-cancer.org/)
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171
Score snapshot 15 Sept 2025
Apple Podcasts (US)
5.0 / 5
1 ratings
Podcast Authority Score: 34 / 100
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YouTube
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