Leading Beyond The Lab

About Leading Beyond The Lab

97% of our listeners don't realise they aren't followed, please double check, thank you! The Leading Beyond The Lab Podcast is hosted by Lawrence Rose, one of the Directors at ARTO, a talent solutions agency specialising in leadership roles within the Life Sciences sector globally. This podcast provides insightful discussions with industry experts, leaders and innovators, shaping the future in drug development and clinical devices. We talk with biotechnology and/or pharmaceutical executives, and find out from them their stories, personal career development and analyse their opinion on how to become successful in this space. We talk on a range of topics including soft skills, oncology, leadership, micromanagement, investment, cardiology, AI, dementia, addiction, hematology, dermatology, and much more. This podcast applies broadly to all types of connections in the Life Sciences Industry, and aims to educate and inspire those who want to excel in leadership. Hosted on Acast. See acast.com/privacy (https://acast.com/privacy) for more information.

Publisher

ARTO Talent

Category

business · health & fitness · science

Language

en

Explicit

No

First episode

11 Dec 2024

Latest episode

16 Jul 2026

Latest episodes

39 episodes in the feed.

1. 

   16 Jul 2026

   The Evolution of Medical Affairs in Global Pharma

   What does it really take to transform Medical Affairs from a scientific support function into one of the biggest strategic drivers in pharmaceutical innovation? In this episode, Vlado Kopernicky, former Senior Vice President of International Medical Affairs at one of the world's leading pharmaceutical companies, shares how a career that began as a neonatologist evolved into helping shape one of the most significant transformations in the pharmaceutical industry. From launching medicines across global markets to redefining the role of Medical Affairs, Vlado reflects on the leadership lessons, commercial mindset and organisational changes that supported extraordinary growth. In this episode, Vlado covers: 03:26 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=206s) How moving from clinical medicine into pharma changed the way decisions are made and why understanding business became essential. 10:27 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=627s) Why Medical Affairs has evolved beyond scientific support into a strategic function responsible for accelerating the adoption of innovation across healthcare. 15:26 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=926s) How Medical Affairs proved its value by measuring impact differently, and why "tell me how you measure me and I will tell you how I behave" changed the conversation. 20:19 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=1219s) Why focus, speed and disciplined decision making become competitive advantages, and the leadership lessons inspired by Steve Jobs' philosophy on prioritisation. 27:43 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=1663s) The career lessons that mattered most, from developing future leaders to recognising that long-term impact extends far beyond individual achievements. If you're interested in pharmaceutical leadership, Medical Affairs, commercial strategy, innovation, or what it takes to build high-performing global organisations, this conversation offers practical insights from someone who has experienced transformation at the highest level. Watch the full episode and join the discussion in the comments. Follow ARTO LinkedIn: / artotalent (https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbFVyRXJmdVl6RDIwbGgxM0VTSm1EYURoUmFFd3xBQ3Jtc0tsOGtJWmZwS2hIckxoRXpVQTFuby1FcHpNT3JxYWhSc29rVXpZQlpzN3dhTXdnQzJJUGF0WDVrWS0wRVpaS0poTXNlUjd1V19jdHZkTlZfVzlhakQxOF9ENlJFSmhHOU5sYUVCaTFlVU1ERW4xVzZERQ&q=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Fartotalent&v=im1KFAoyPC0) Spotify: https://open.spotify.com/show/0kEcRZO... (https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbVczcnliRUFfYXJhZ1V1V0FKUkpyY21IcWE4QXxBQ3Jtc0tuMU56LUhoVVNWZUwtekNqZzRQZ1lhQk5HMDE5MXpjYjRsZFczV0k0cWZuRVlDUURUcURGcmxkTmUzODc1ZE5qVEpIeEd1OUJyMzRnN1JndFlhbnhGZGZwX0RhN1hIdmd4MGxzMDdzc3MwLVZyczFZUQ&q=https%3A%2F%2Fopen.spotify.com%2Fshow%2F0kEcRZOiJChOoN1KF2n1ng&v=im1KFAoyPC0) Instagram: https://www.instagram.com/arto.talent... (https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbkZ0SlNlZlY4SU9aVVdYbjNZeThoR3JvT2s5d3xBQ3Jtc0ttcTh6VlcyV1VlVEJfNkJtd3EySlBWd0dZdDU5UFJfOTRWUl9LMC01UkllckFsZlVLR3p1X21pWnhXMXdvUHdFd0lXNDlvWFZlNktIYjVoTG9IVFZIRmNJOE1IN051MUpBelZVUDlQMGFjdlpXalh0MA&q=https%3A%2F%2Fwww.instagram.com%2Farto.talent%3Figsh%3DMWdhbWl5N204a253NQ%253D%253D%26utm_source%3Dqr&v=im1KFAoyPC0) TikTok: https://www.tiktok.com/@artotalent?_t... (https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqblQzRVkzTnpaRFh0bnh2TnFMRzhOd2xyeTJjUXxBQ3Jtc0trSFlWUUdNYS00OHNPLWtBUVdVUjFTWFB1QTd4WG8yTkdKLU94ajhxUHRVdVpvTjJfaHNDS1ltZGJDODZOZ0c1ZWFIdnZNSnRiM1ZpQnN0LUVTOU9kTjJmV3Zzb1I5eGdQZ3pzUmQ0NDV6UjJqOVRHTQ&q=https%3A%2F%2Fwww.tiktok.com%2F%40artotalent%3F_t%3DZG-8tHbGACAZaj%26_r%3D1&v=im1KFAoyPC0) Apple Podcasts: https://podcasts.apple.com/us/podcast... (https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbG5LbEpzNzJCR1A5aU1XU3RmcUVZY3VMdzFkUXxBQ3Jtc0trM2JoclY5Z3piVXRfR0hSdThUT2h5WXU0V3JuTWdLckFoQUczeGRQTk16YUYwYjM5NkZ1am5wbHo3V0dTRm1Ka2JGM1MtcHhpSDdWb3A0Rm5jUm1ud2J5Y3lGanVuT0hGRDkyb0tuUElPaHVtclpTNA&q=https%3A%2F%2Fpodcasts.apple.com%2Fus%2Fpodcast%2Fleading-beyond-the-lab%2Fid1783115575&v=im1KFAoyPC0) Website: https://arto-talent.com/ (https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbHp3aUNGZkFLTDBkWkZLRC1hdEhXTHBYLS1kd3xBQ3Jtc0trSjFTd3NEbUpGYm4tci0xQjFhTEpJeGhFODlNenZ3ZUJUWkNCQzIzd01RMlRzdno5cXZvaGlYTVNlRnM4MWdPOVF2LWNkNDBsNWM1U2hKVGpEYU9DTjk5UWxzeU1zaDEtM24tM3l1TnQ2Vm84T2duYw&q=https%3A%2F%2Farto-talent.com%2F&v=im1KFAoyPC0) YouTube: / @artotalent (https://www.youtube.com/channel/UCkoSWF_xqX4i9OIkX4pGaxQ) Vlado Kopernicky LinkedIn: / vlado-kopernicky-b7326925 (https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbHQ1SjRhdUJsWXBfblBuTVNNOXU4M1FLNWIzd3xBQ3Jtc0ttaktDVVlacjBSbEd4YUhzX2VNcl9DRFQzT2RvSW40U2Jnb20yclBxNzVmWFZfalFESEQ2WGVJZHVlTDFZWml2QkhnNXRRTURLZUxzMVZLd0pOZUEtb3ppZ1FSSmFoTkUtLXFmSE1iVE1zSUNjSV9Ibw&q=https%3A%2F%2Fwww.linkedin.com%2Fin%2Fvlado-kopernicky-b7326925%2F&v=im1KFAoyPC0) Lawrence Rose LinkedIn: / lawrencerose (https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbEVNNWM5S2JtSkg5MkxnWS16S0FFQXZWWWlnd3xBQ3Jtc0tuR3M3MzRRZlFBekd0cHlfa25Pc0xXQ19xMVlLZ3VvUmc2VXo5LS1IbUR1NjQxMS13dnBnX3NnVVo2WUc3dDZLSTQxaWpGOG1teDUtTDZWNy1IVkRrU1N6TmhtTHM2QTVFZmEzUDV1NW5QTGd6VFVWRQ&q=https%3A%2F%2Fwww.linkedin.com%2Fin%2Flawrencerose%2F&v=im1KFAoyPC0) Timestamps: 00:00 (https://www.youtube.com/watch?v=im1KFAoyPC0) Introduction 01:53 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=113s) From neonatology into pharma 03:26 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=206s) Learning the business of pharma 06:26 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=386s) Launching medicines in a competitive market 09:05 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=545s) Building brands that resonate with patients 10:27 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=627s) The evolution of Medical Affairs 12:20 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=740s) The pharma business model and adoption of innovation 15:26 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=926s) Measuring the value of Medical Affairs 20:19 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=1219s) Focus, speed and competitive advantage 22:30 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=1350s) Leading transformation and helping people embrace change 24:21 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=1461s) The future of Medical Affairs leadership 27:43 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=1663s) Career milestones and leadership legacy 29:58 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=1798s) The impact of innovation on patient outcomes 31:51 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=1911s) Advice for future transformation leaders 33:12 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=1992s) Mentors and leadership lessons 34:45 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=2085s) The advice that shaped Vlado's career 36:06 (https://www.youtube.com/watch?v=im1KFAoyPC0&t=2166s) Final thoughts #leadingbeyondthelab (https://www.youtube.com/hashtag/leadingbeyondthelab) #ARTOTalent (https://www.youtube.com/hashtag/artotalent) #MedicalAffairs (https://www.youtube.com/hashtag/medicalaffairs) #PharmaceuticalIndustry (https://www.youtube.com/hashtag/pharmaceuticalindustry) #PharmaLeadership (https://www.youtube.com/hashtag/pharmaleadership) #LifeSciences (https://www.youtube.com/hashtag/lifesciences) #Biotech (https://www.youtube.com/hashtag/biotech) #HealthcareInnovation (https://www.youtube.com/hashtag/healthcareinnovation) #DrugDevelopment (https://www.youtube.com/hashtag/drugdevelopment) #Leadership (https://www.youtube.com/hashtag/leadership) #CommercialStrategy (https://www.youtube.com/hashtag/commercialstrategy) #Innovation (https://www.youtube.com/hashtag/innovation) Hosted on Acast. See acast.com/privacy (https://acast.com/privacy) for more information.

2. 

   25 Jun 2026

   How One AI Platform Is Cutting Years Off Drug Discovery - Yann Gaston-Mathé

   95% of our viewers aren't subscribed. If you're watching and not yet subscribed, please subscribe to the channel so you don't miss future episodes. What does it take to improve a drug discovery success rate of less than 1%? In this episode, Yann Gaston-Mathé explains how AI, robotics, and laboratory automation are being combined to accelerate the development of new medicines and tackle some of the industry's most challenging drug targets. This week on Leading Beyond The Lab, Lawrence Rose sat down with Yann Gaston-Mathé, CEO and Co-Founder of Iktos, with more than 20 years of experience spanning pharmaceutical R&D, data science, IT, strategic consulting, entrepreneurship, and AI-driven drug discovery. In this episode, Yann Gaston-Mathé covers: • How Iktos is tackling the inefficiency of small molecule drug discovery and why overall success rates remain below 1% • What differentiates Iktos from other AI drug discovery companies by combining generative AI with laboratory automation and robotic synthesis • The journey from large pharmaceutical organisations into entrepreneurship and the founding story behind Iktos in 2016 • How AI, predictive modelling, robotics and iterative design-make-test cycles are transforming drug discovery workflows • Why the next frontier for AI in healthcare is improving clinical success rates and reducing development timelines that currently take 8 to 10 years Yann provides a practical perspective on where AI is creating real value in drug discovery, the importance of combining software with experimental science, and why human expertise remains central to the future of pharmaceutical innovation. If you're interested in AI, biotechnology, drug discovery, pharmaceutical R&D, laboratory automation, or the future of healthcare innovation, this episode offers valuable insight from someone building and deploying these technologies today. Throughout the conversation, Lawrence and Yann discuss the evolution of @Iktos, collaborations across the pharmaceutical industry, and lessons learned from working with global pharmaceutical and biotechnology partners. Follow ARTO LinkedIn: https://www.linkedin.com/company/artotalent Spotify: https://open.spotify.com/show/0kEcRZOiJChOoN1KF2n1ng Instagram: https://www.instagram.com/arto.talent?igsh=MWdhbWl5N204a253NQ%3D%3D&utm_source=qr TikTok: https://www.tiktok.com/@artotalent?_t=ZG-8tHbGACAZaj&_r=1 Apple Podcasts: https://podcasts.apple.com/us/podcast/leading-beyond-the-lab/id1783115575 Website: https://arto-talent.com/ Youtube: https://www.youtube.com/@artotalent Yann Gaston-Mathé LinkedIn: https://www.linkedin.com/in/yann-gaston-mathe-9850a21/ Lawrence Rose LinkedIn: https://www.linkedin.com/in/lawrencerose/ Timestamps: 00:00 Introduction and episode highlights 01:37 Welcome to Leading Beyond The Lab 07:19 The founding story behind Iktos 08:05 Career journey through pharma, consulting, IT and data science 10:09 Leaving large pharmaceutical companies for entrepreneurship 11:10 How the Iktos platform works 16:41 Automation and scaling medicinal chemistry workflows 22:03 Measuring impact, speed and efficiency in drug discovery 26:19 Competition within AI drug discovery 27:30 The future of AI in pharmaceutical R&D 29:35 Building strategic pharmaceutical partnerships 30:52 Evaluating new collaboration opportunities 32:18 Working across global cultures and organisations 33:35 Creating value through partnerships 35:45 Scaling resources and managing growth 41:09 Challenges in building automated laboratory infrastructure 42:12 Will AI replace chemists? 45:29 Will AI ever fully replace human scientists? 47:59 What continues to motivate Yann Gaston-Mathé 49:24 Advice for the next generation of scientists 50:38 Science, technology and the future workforce 51:06 Closing remarks #LeadingBeyondTheLab #ARTOTalent #DrugDiscovery #ArtificialIntelligence #Biotech #Pharmaceuticals #LifeSciences #LaboratoryAutomation #MachineLearning #HealthcareInnovation #DrugDevelopment #GenerativeAI Hosted on Acast. See acast.com/privacy (https://acast.com/privacy) for more information.

3. 

   1 Jun 2026

   The Next Generation of Autoimmune Therapies? Inside SciRhom’s IRhom2 Platform

   95% of our viewers aren’t subscribed. If you’re watching and not yet subscribed, please subscribe to the channel so you don’t miss future episodes. Can targeting IRhom2 unlock a new generation of autoimmune disease treatments? This week on Leading Beyond The Lab, Lawrence Rose sat down with Jan Poth and Jens Ruhe of SciRhom, discussing a new therapeutic approach focused on IRhom2 and TACE inhibition in autoimmune disease. The conversation explored the scientific origins of the company, lessons from failed inflammatory pathway inhibitors, and the challenge of building a biotech platform in one of the toughest funding environments in recent years. In this episode, Jan Poth and Jens Ruhe cover: • Why previous TACE inhibitors failed and how targeting IRhom2 could offer a more selective approach to inflammatory diseases • The scientific breakthrough that convinced the founding team IRhom2 could be druggable despite industry skepticism at the time (Carl Blobel, Hospital for Special Surgery) • Why combining multiple inflammatory pathways may be necessary to move beyond the efficacy ceiling seen with TNF and IL-6 inhibitors • How the company secured an oversubscribed Series A after speaking with more than 150 investors over two years, with backing from Wellington Partners, Hadean Ventures, Kurma Partners, Andera Partners, MIG Capital, Bain Capital, and HTGF • The roadmap for S878, expectations for the upcoming Phase I trial in rheumatoid arthritis patients, and the long-term ambition to become the defining company in IRhom2 therapeutics. This episode offers a detailed look into modern biotech company building, translational immunology, and the realities of advancing a first-in-class therapeutic platform from concept to clinic. If you are interested in autoimmune disease innovation, antibody development, biotech financing, or platform company strategy, this conversation is well worth your time. Follow ARTO LinkedIn: https://www.linkedin.com/company/artotalent Spotify: https://open.spotify.com/show/0kEcRZOiJChOoN1KF2n1ng Instagram: https://www.instagram.com/arto.talent?igsh=MWdhbWl5N204a253NQ%3D%3D&utm_source=qr TikTok: https://www.tiktok.com/@artotalent?_t=ZG-8tHbGACAZaj&_r=1 Apple Podcasts: https://podcasts.apple.com/us/podcast/leading-beyond-the-lab/id1783115575 Website: https://arto-talent.com/ Youtube: https://www.youtube.com/@artotalent Jan Poth & Jens Ruhe CEO & COO at SciRhom LinkedIn: https://www.linkedin.com/in/jan-poth-a79424136/ LinkedIn: https://www.linkedin.com/in/jens-ruhe/ Lawrence Rose LinkedIn: https://www.linkedin.com/in/lawrencerose/ Timestamps: 00:00 Introduction to immune system complexity and inflammatory disease challenges 01:38 Podcast introduction and overview of SciRhom’s approach 02:30 The origins of targeting IRhom2 and TACE 05:20 The founding of SciRhom and early scientific conviction 06:39 Discovering IRhom2 surface accessibility with Carl Blobel 08:26 Combining inflammatory pathway inhibition 12:14 Complexity of the immune system and autoimmune disease treatment 14:20 Why single pathway inhibitors reach an efficacy ceiling 18:15 Raising a successful Series A in a difficult biotech market 20:23 Overview of lead candidate S878 and upcoming Phase I trial 24:15 Fundraising challenges and early investor support from HTGF 31:47 Key milestones and expectations for Phase I readouts 34:22 Building a pipeline around IRhom2 biology 35:24 Balancing speed, capital efficiency, and scientific rigor 39:55 Founder dynamics and collaborative decision-making 43:12 Bringing commercial development expertise into biotech strategy 49:11 Balancing patient impact with commercial success 49:45 Long-term vision for SciRhom and IRhom2 therapeutics 52:30 AI, technology, and reducing drug development costs 55:11 Shared mission and improving outcomes for autoimmune disease patients 56:34 Closing remarks #LeadingBeyondTheLab #ARTOTalent #Biotech #Immunology #AutoimmuneDisease #DrugDevelopment #AntibodyTherapeutics #RheumatoidArthritis #LifeSciences Hosted on Acast. See acast.com/privacy (https://acast.com/privacy) for more information.

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137,330

Score snapshot 15 Sept 2025

Podcast Authority Score: 65 / 100

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Quality

81

Social presence

97

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76

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0

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