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Leading Beyond The Lab

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by ARTO Talent

39 episodes
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Podcast Overview

<p>97% of our listeners don't realise they aren't followed, please double check, thank you!</p><br><p>The <strong>Leading Beyond The Lab </strong>Podcast is hosted by Lawrence Rose, one of the Directors at <strong>ARTO</strong>, a talent solutions agency specialising in leadership roles within the Life Sciences sector globally.</p><br><p>This podcast provides insightful discussions with industry experts, leaders and innovators, shaping the future in drug development and clinical devices. We talk with biotechnology and/or pharmaceutical executives, and find out from them their stories, personal career development and analyse their opinion on how to become successful in this space. We talk on a range of topics including soft skills, oncology, leadership, micromanagement, investment, cardiology, AI, dementia, addiction, hematology, dermatology, and much more.</p><br><p><strong>This podcast applies broadly to all types of connections in the Life Sciences Industry, and aims to educate and inspire those who want to excel in leadership.&nbsp;</strong></p><hr><p style='color:grey; font-size:0.75em;'> Hosted on Acast. See <a style='color:grey;' target='_blank' rel='noopener noreferrer' href='https://acast.com/privacy'>acast.com/privacy</a> for more information.</p>

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12/11/2024

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Recent Episodes

Episode thumbnail for The Evolution of Medical Affairs in Global Pharma

July 16, 2026

The Evolution of Medical Affairs in Global Pharma

<p>What does it really take to transform Medical Affairs from a scientific support function into one of the biggest strategic drivers in pharmaceutical innovation?</p><br><p>In this episode, Vlado Kopernicky, former Senior Vice President of International Medical Affairs at one of the world's leading pharmaceutical companies, shares how a career that began as a neonatologist evolved into helping shape one of the most significant transformations in the pharmaceutical industry.</p><br><p>From launching medicines across global markets to redefining the role of Medical Affairs, Vlado reflects on the leadership lessons, commercial mindset and organisational changes that supported extraordinary growth.</p><br><p>In this episode, Vlado covers:</p><br><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=206s" rel="noopener noreferrer" target="_blank">03:26</a> How moving from clinical medicine into pharma changed the way decisions are made and why understanding business became essential.</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=627s" rel="noopener noreferrer" target="_blank">10:27</a> Why Medical Affairs has evolved beyond scientific support into a strategic function responsible for accelerating the adoption of innovation across healthcare.</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=926s" rel="noopener noreferrer" target="_blank">15:26</a> How Medical Affairs proved its value by measuring impact differently, and why "tell me how you measure me and I will tell you how I behave" changed the conversation.</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=1219s" rel="noopener noreferrer" target="_blank">20:19</a> Why focus, speed and disciplined decision making become competitive advantages, and the leadership lessons inspired by Steve Jobs' philosophy on prioritisation.</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=1663s" rel="noopener noreferrer" target="_blank">27:43</a> The career lessons that mattered most, from developing future leaders to recognising that long-term impact extends far beyond individual achievements.</p><br><p>If you're interested in pharmaceutical leadership, Medical Affairs, commercial strategy, innovation, or what it takes to build high-performing global organisations, this conversation offers practical insights from someone who has experienced transformation at the highest level.</p><br><p>Watch the full episode and join the discussion in the comments.</p><p>Follow ARTO</p><p>LinkedIn: <a href="https://www.youtube.com/redirect?event=video_description&amp;redir_token=QUFFLUhqbFVyRXJmdVl6RDIwbGgxM0VTSm1EYURoUmFFd3xBQ3Jtc0tsOGtJWmZwS2hIckxoRXpVQTFuby1FcHpNT3JxYWhSc29rVXpZQlpzN3dhTXdnQzJJUGF0WDVrWS0wRVpaS0poTXNlUjd1V19jdHZkTlZfVzlhakQxOF9ENlJFSmhHOU5sYUVCaTFlVU1ERW4xVzZERQ&amp;q=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Fartotalent&amp;v=im1KFAoyPC0" rel="noopener noreferrer" target="_blank">&nbsp;<img src="https://www.gstatic.com/youtube/img/watch/social_media/linkedin_1x.png">&nbsp;/&nbsp;artotalent&nbsp;&nbsp;</a></p><p>Spotify: <a href="https://www.youtube.com/redirect?event=video_description&amp;redir_token=QUFFLUhqbVczcnliRUFfYXJhZ1V1V0FKUkpyY21IcWE4QXxBQ3Jtc0tuMU56LUhoVVNWZUwtekNqZzRQZ1lhQk5HMDE5MXpjYjRsZFczV0k0cWZuRVlDUURUcURGcmxkTmUzODc1ZE5qVEpIeEd1OUJyMzRnN1JndFlhbnhGZGZwX0RhN1hIdmd4MGxzMDdzc3MwLVZyczFZUQ&amp;q=https%3A%2F%2Fopen.spotify.com%2Fshow%2F0kEcRZOiJChOoN1KF2n1ng&amp;v=im1KFAoyPC0" rel="noopener noreferrer" target="_blank">https://open.spotify.com/show/0kEcRZO...</a></p><p>Instagram: <a href="https://www.youtube.com/redirect?event=video_description&amp;redir_token=QUFFLUhqbkZ0SlNlZlY4SU9aVVdYbjNZeThoR3JvT2s5d3xBQ3Jtc0ttcTh6VlcyV1VlVEJfNkJtd3EySlBWd0dZdDU5UFJfOTRWUl9LMC01UkllckFsZlVLR3p1X21pWnhXMXdvUHdFd0lXNDlvWFZlNktIYjVoTG9IVFZIRmNJOE1IN051MUpBelZVUDlQMGFjdlpXalh0MA&amp;q=https%3A%2F%2Fwww.instagram.com%2Farto.talent%3Figsh%3DMWdhbWl5N204a253NQ%253D%253D%26utm_source%3Dqr&amp;v=im1KFAoyPC0" rel="noopener noreferrer" target="_blank">https://www.instagram.com/arto.talent...</a></p><p>TikTok: <a href="https://www.youtube.com/redirect?event=video_description&amp;redir_token=QUFFLUhqblQzRVkzTnpaRFh0bnh2TnFMRzhOd2xyeTJjUXxBQ3Jtc0trSFlWUUdNYS00OHNPLWtBUVdVUjFTWFB1QTd4WG8yTkdKLU94ajhxUHRVdVpvTjJfaHNDS1ltZGJDODZOZ0c1ZWFIdnZNSnRiM1ZpQnN0LUVTOU9kTjJmV3Zzb1I5eGdQZ3pzUmQ0NDV6UjJqOVRHTQ&amp;q=https%3A%2F%2Fwww.tiktok.com%2F%40artotalent%3F_t%3DZG-8tHbGACAZaj%26_r%3D1&amp;v=im1KFAoyPC0" rel="noopener noreferrer" target="_blank">https://www.tiktok.com/@artotalent?_t...</a></p><p>Apple Podcasts: <a href="https://www.youtube.com/redirect?event=video_description&amp;redir_token=QUFFLUhqbG5LbEpzNzJCR1A5aU1XU3RmcUVZY3VMdzFkUXxBQ3Jtc0trM2JoclY5Z3piVXRfR0hSdThUT2h5WXU0V3JuTWdLckFoQUczeGRQTk16YUYwYjM5NkZ1am5wbHo3V0dTRm1Ka2JGM1MtcHhpSDdWb3A0Rm5jUm1ud2J5Y3lGanVuT0hGRDkyb0tuUElPaHVtclpTNA&amp;q=https%3A%2F%2Fpodcasts.apple.com%2Fus%2Fpodcast%2Fleading-beyond-the-lab%2Fid1783115575&amp;v=im1KFAoyPC0" rel="noopener noreferrer" target="_blank">https://podcasts.apple.com/us/podcast...</a></p><p>Website: <a href="https://www.youtube.com/redirect?event=video_description&amp;redir_token=QUFFLUhqbHp3aUNGZkFLTDBkWkZLRC1hdEhXTHBYLS1kd3xBQ3Jtc0trSjFTd3NEbUpGYm4tci0xQjFhTEpJeGhFODlNenZ3ZUJUWkNCQzIzd01RMlRzdno5cXZvaGlYTVNlRnM4MWdPOVF2LWNkNDBsNWM1U2hKVGpEYU9DTjk5UWxzeU1zaDEtM24tM3l1TnQ2Vm84T2duYw&amp;q=https%3A%2F%2Farto-talent.com%2F&amp;v=im1KFAoyPC0" rel="noopener noreferrer" target="_blank">https://arto-talent.com/</a></p><p>YouTube: <a href="https://www.youtube.com/channel/UCkoSWF_xqX4i9OIkX4pGaxQ" rel="noopener noreferrer" target="_blank">&nbsp;&nbsp;<img src="https://www.gstatic.com/youtube/img/watch/yt_favicon_ringo2.png">&nbsp;/&nbsp;@artotalent&nbsp;&nbsp;</a></p><p>Vlado Kopernicky LinkedIn: <a href="https://www.youtube.com/redirect?event=video_description&amp;redir_token=QUFFLUhqbHQ1SjRhdUJsWXBfblBuTVNNOXU4M1FLNWIzd3xBQ3Jtc0ttaktDVVlacjBSbEd4YUhzX2VNcl9DRFQzT2RvSW40U2Jnb20yclBxNzVmWFZfalFESEQ2WGVJZHVlTDFZWml2QkhnNXRRTURLZUxzMVZLd0pOZUEtb3ppZ1FSSmFoTkUtLXFmSE1iVE1zSUNjSV9Ibw&amp;q=https%3A%2F%2Fwww.linkedin.com%2Fin%2Fvlado-kopernicky-b7326925%2F&amp;v=im1KFAoyPC0" rel="noopener noreferrer" target="_blank">&nbsp;<img src="https://www.gstatic.com/youtube/img/watch/social_media/linkedin_1x.png">&nbsp;/&nbsp;vlado-kopernicky-b7326925&nbsp;&nbsp;</a></p><p>Lawrence Rose LinkedIn: <a href="https://www.youtube.com/redirect?event=video_description&amp;redir_token=QUFFLUhqbEVNNWM5S2JtSkg5MkxnWS16S0FFQXZWWWlnd3xBQ3Jtc0tuR3M3MzRRZlFBekd0cHlfa25Pc0xXQ19xMVlLZ3VvUmc2VXo5LS1IbUR1NjQxMS13dnBnX3NnVVo2WUc3dDZLSTQxaWpGOG1teDUtTDZWNy1IVkRrU1N6TmhtTHM2QTVFZmEzUDV1NW5QTGd6VFVWRQ&amp;q=https%3A%2F%2Fwww.linkedin.com%2Fin%2Flawrencerose%2F&amp;v=im1KFAoyPC0" rel="noopener noreferrer" target="_blank">&nbsp;<img src="https://www.gstatic.com/youtube/img/watch/social_media/linkedin_1x.png">&nbsp;/&nbsp;lawrencerose&nbsp;&nbsp;</a></p><br><p>Timestamps:</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0" rel="noopener noreferrer" target="_blank">00:00</a> Introduction</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=113s" rel="noopener noreferrer" target="_blank">01:53</a> From neonatology into pharma</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=206s" rel="noopener noreferrer" target="_blank">03:26</a> Learning the business of pharma</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=386s" rel="noopener noreferrer" target="_blank">06:26</a> Launching medicines in a competitive market</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=545s" rel="noopener noreferrer" target="_blank">09:05</a> Building brands that resonate with patients</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=627s" rel="noopener noreferrer" target="_blank">10:27</a> The evolution of Medical Affairs</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=740s" rel="noopener noreferrer" target="_blank">12:20</a> The pharma business model and adoption of innovation</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=926s" rel="noopener noreferrer" target="_blank">15:26</a> Measuring the value of Medical Affairs</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=1219s" rel="noopener noreferrer" target="_blank">20:19</a> Focus, speed and competitive advantage</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=1350s" rel="noopener noreferrer" target="_blank">22:30</a> Leading transformation and helping people embrace change</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=1461s" rel="noopener noreferrer" target="_blank">24:21</a> The future of Medical Affairs leadership</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=1663s" rel="noopener noreferrer" target="_blank">27:43</a> Career milestones and leadership legacy</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=1798s" rel="noopener noreferrer" target="_blank">29:58</a> The impact of innovation on patient outcomes</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=1911s" rel="noopener noreferrer" target="_blank">31:51</a> Advice for future transformation leaders</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=1992s" rel="noopener noreferrer" target="_blank">33:12</a> Mentors and leadership lessons</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=2085s" rel="noopener noreferrer" target="_blank">34:45</a> The advice that shaped Vlado's career</p><p><a href="https://www.youtube.com/watch?v=im1KFAoyPC0&amp;t=2166s" rel="noopener noreferrer" target="_blank">36:06</a> Final thoughts</p><br><p><a href="https://www.youtube.com/hashtag/leadingbeyondthelab" rel="noopener noreferrer" target="_blank">#leadingbeyondthelab</a> <a href="https://www.youtube.com/hashtag/artotalent" rel="noopener noreferrer" target="_blank">#ARTOTalent</a> <a href="https://www.youtube.com/hashtag/medicalaffairs" rel="noopener noreferrer" target="_blank">#MedicalAffairs</a> <a href="https://www.youtube.com/hashtag/pharmaceuticalindustry" rel="noopener noreferrer" target="_blank">#PharmaceuticalIndustry</a> <a href="https://www.youtube.com/hashtag/pharmaleadership" rel="noopener noreferrer" target="_blank">#PharmaLeadership</a> <a href="https://www.youtube.com/hashtag/lifesciences" rel="noopener noreferrer" target="_blank">#LifeSciences</a> <a href="https://www.youtube.com/hashtag/biotech" rel="noopener noreferrer" target="_blank">#Biotech</a> <a href="https://www.youtube.com/hashtag/healthcareinnovation" rel="noopener noreferrer" target="_blank">#HealthcareInnovation</a> <a href="https://www.youtube.com/hashtag/drugdevelopment" rel="noopener noreferrer" target="_blank">#DrugDevelopment</a> <a href="https://www.youtube.com/hashtag/leadership" rel="noopener noreferrer" target="_blank">#Leadership</a> <a href="https://www.youtube.com/hashtag/commercialstrategy" rel="noopener noreferrer" target="_blank">#CommercialStrategy</a> <a href="https://www.youtube.com/hashtag/innovation" rel="noopener noreferrer" target="_blank">#Innovation</a></p><hr><p style='color:grey; font-size:0.75em;'> Hosted on Acast. See <a style='color:grey;' target='_blank' rel='noopener noreferrer' href='https://acast.com/privacy'>acast.com/privacy</a> for more information.</p>

Episode thumbnail for How One AI Platform Is Cutting Years Off Drug Discovery - Yann Gaston-Mathé

June 25, 2026

How One AI Platform Is Cutting Years Off Drug Discovery - Yann Gaston-Mathé

<p>95% of our viewers aren't subscribed. If you're watching and not yet subscribed, please subscribe to the channel so you don't miss future episodes.</p><br><p>What does it take to improve a drug discovery success rate of less than 1%? In this episode, Yann Gaston-Mathé explains how AI, robotics, and laboratory automation are being combined to accelerate the development of new medicines and tackle some of the industry's most challenging drug targets.</p><br><p>This week on Leading Beyond The Lab, Lawrence Rose sat down with Yann Gaston-Mathé, CEO and Co-Founder of Iktos, with more than 20 years of experience spanning pharmaceutical R&amp;D, data science, IT, strategic consulting, entrepreneurship, and AI-driven drug discovery.</p><br><p>In this episode, Yann Gaston-Mathé covers:</p><br><p>• How Iktos is tackling the inefficiency of small molecule drug discovery and why overall success rates remain below 1% </p><br><p>• What differentiates Iktos from other AI drug discovery companies by combining generative AI with laboratory automation and robotic synthesis</p><br><p>• The journey from large pharmaceutical organisations into entrepreneurship and the founding story behind Iktos in 2016 </p><br><p>• How AI, predictive modelling, robotics and iterative design-make-test cycles are transforming drug discovery workflows </p><br><p>• Why the next frontier for AI in healthcare is improving clinical success rates and reducing development timelines that currently take 8 to 10 years </p><br><p>Yann provides a practical perspective on where AI is creating real value in drug discovery, the importance of combining software with experimental science, and why human expertise remains central to the future of pharmaceutical innovation.</p><br><p>If you're interested in AI, biotechnology, drug discovery, pharmaceutical R&amp;D, laboratory automation, or the future of healthcare innovation, this episode offers valuable insight from someone building and deploying these technologies today.</p><br><p>Throughout the conversation, Lawrence and Yann discuss the evolution of @Iktos, collaborations across the pharmaceutical industry, and lessons learned from working with global pharmaceutical and biotechnology partners.</p><br><p>Follow ARTO</p><br><p>LinkedIn: https://www.linkedin.com/company/artotalent</p><p>Spotify: https://open.spotify.com/show/0kEcRZOiJChOoN1KF2n1ng</p><p>Instagram: https://www.instagram.com/arto.talent?igsh=MWdhbWl5N204a253NQ%3D%3D&amp;utm_source=qr</p><p>TikTok: https://www.tiktok.com/@artotalent?_t=ZG-8tHbGACAZaj&amp;_r=1</p><p>Apple Podcasts: https://podcasts.apple.com/us/podcast/leading-beyond-the-lab/id1783115575</p><p>Website: https://arto-talent.com/</p><p>Youtube: https://www.youtube.com/@artotalent</p><br><p>Yann Gaston-Mathé</p><br><p>LinkedIn: https://www.linkedin.com/in/yann-gaston-mathe-9850a21/</p><br><p>Lawrence Rose</p><br><p>LinkedIn: https://www.linkedin.com/in/lawrencerose/</p><br><p>Timestamps:</p><br><p>00:00 Introduction and episode highlights</p><p>01:37 Welcome to Leading Beyond The Lab</p><p>07:19 The founding story behind Iktos</p><p>08:05 Career journey through pharma, consulting, IT and data science</p><p>10:09 Leaving large pharmaceutical companies for entrepreneurship</p><p>11:10 How the Iktos platform works</p><p>16:41 Automation and scaling medicinal chemistry workflows</p><p>22:03 Measuring impact, speed and efficiency in drug discovery</p><p>26:19 Competition within AI drug discovery</p><p>27:30 The future of AI in pharmaceutical R&amp;D</p><p>29:35 Building strategic pharmaceutical partnerships</p><p>30:52 Evaluating new collaboration opportunities</p><p>32:18 Working across global cultures and organisations</p><p>33:35 Creating value through partnerships</p><p>35:45 Scaling resources and managing growth</p><p>41:09 Challenges in building automated laboratory infrastructure</p><p>42:12 Will AI replace chemists?</p><p>45:29 Will AI ever fully replace human scientists?</p><p>47:59 What continues to motivate Yann Gaston-Mathé</p><p>49:24 Advice for the next generation of scientists</p><p>50:38 Science, technology and the future workforce</p><p>51:06 Closing remarks</p><br><p>#LeadingBeyondTheLab #ARTOTalent #DrugDiscovery #ArtificialIntelligence #Biotech #Pharmaceuticals #LifeSciences #LaboratoryAutomation #MachineLearning #HealthcareInnovation #DrugDevelopment #GenerativeAI</p><hr><p style='color:grey; font-size:0.75em;'> Hosted on Acast. See <a style='color:grey;' target='_blank' rel='noopener noreferrer' href='https://acast.com/privacy'>acast.com/privacy</a> for more information.</p>

Episode thumbnail for The Next Generation of Autoimmune Therapies? Inside SciRhom’s IRhom2 Platform

June 1, 2026

The Next Generation of Autoimmune Therapies? Inside SciRhom’s IRhom2 Platform

<p>95% of our viewers aren’t subscribed. If you’re watching and not yet subscribed, please subscribe to the channel so you don’t miss future episodes.</p><br><p>Can targeting IRhom2 unlock a new generation of autoimmune disease treatments?</p><br><p>This week on Leading Beyond The Lab, Lawrence Rose sat down with Jan Poth and Jens Ruhe of SciRhom, discussing a new therapeutic approach focused on IRhom2 and TACE inhibition in autoimmune disease. </p><br><p>The conversation explored the scientific origins of the company, lessons from failed inflammatory pathway inhibitors, and the challenge of building a biotech platform in one of the toughest funding environments in recent years.</p><br><p>In this episode, Jan Poth and Jens Ruhe cover:</p><br><p>• Why previous TACE inhibitors failed and how targeting IRhom2 could offer a more selective approach to inflammatory diseases</p><br><p>• The scientific breakthrough that convinced the founding team IRhom2 could be druggable despite industry skepticism at the time (Carl Blobel, Hospital for Special Surgery) </p><br><p>• Why combining multiple inflammatory pathways may be necessary to move beyond the efficacy ceiling seen with TNF and IL-6 inhibitors </p><br><p>• How the company secured an oversubscribed Series A after speaking with more than 150 investors over two years, with backing from Wellington Partners, Hadean Ventures, Kurma Partners, Andera Partners, MIG Capital, Bain Capital, and HTGF</p><br><p>• The roadmap for S878, expectations for the upcoming Phase I trial in rheumatoid arthritis patients, and the long-term ambition to become the defining company in IRhom2 therapeutics.</p><br><p>This episode offers a detailed look into modern biotech company building, translational immunology, and the realities of advancing a first-in-class therapeutic platform from concept to clinic. If you are interested in autoimmune disease innovation, antibody development, biotech financing, or platform company strategy, this conversation is well worth your time.</p><br><p>Follow ARTO</p><p>LinkedIn: https://www.linkedin.com/company/artotalent</p><p>Spotify: https://open.spotify.com/show/0kEcRZOiJChOoN1KF2n1ng</p><p>Instagram: https://www.instagram.com/arto.talent?igsh=MWdhbWl5N204a253NQ%3D%3D&amp;utm_source=qr</p><p>TikTok: https://www.tiktok.com/@artotalent?_t=ZG-8tHbGACAZaj&amp;_r=1</p><p>Apple Podcasts: https://podcasts.apple.com/us/podcast/leading-beyond-the-lab/id1783115575</p><p>Website: https://arto-talent.com/</p><p>Youtube: https://www.youtube.com/@artotalent</p><br><p>Jan Poth &amp; Jens Ruhe</p><p>CEO &amp; COO at SciRhom</p><p>LinkedIn: https://www.linkedin.com/in/jan-poth-a79424136/</p><p>LinkedIn: https://www.linkedin.com/in/jens-ruhe/</p><br><p>Lawrence Rose</p><p>LinkedIn: https://www.linkedin.com/in/lawrencerose/</p><br><p>Timestamps:</p><p>00:00 Introduction to immune system complexity and inflammatory disease challenges</p><p>01:38 Podcast introduction and overview of SciRhom’s approach</p><p>02:30 The origins of targeting IRhom2 and TACE</p><p>05:20 The founding of SciRhom and early scientific conviction</p><p>06:39 Discovering IRhom2 surface accessibility with Carl Blobel</p><p>08:26 Combining inflammatory pathway inhibition</p><p>12:14 Complexity of the immune system and autoimmune disease treatment</p><p>14:20 Why single pathway inhibitors reach an efficacy ceiling</p><p>18:15 Raising a successful Series A in a difficult biotech market</p><p>20:23 Overview of lead candidate S878 and upcoming Phase I trial</p><p>24:15 Fundraising challenges and early investor support from HTGF</p><p>31:47 Key milestones and expectations for Phase I readouts</p><p>34:22 Building a pipeline around IRhom2 biology</p><p>35:24 Balancing speed, capital efficiency, and scientific rigor</p><p>39:55 Founder dynamics and collaborative decision-making</p><p>43:12 Bringing commercial development expertise into biotech strategy</p><p>49:11 Balancing patient impact with commercial success</p><p>49:45 Long-term vision for SciRhom and IRhom2 therapeutics</p><p>52:30 AI, technology, and reducing drug development costs</p><p>55:11 Shared mission and improving outcomes for autoimmune disease patients</p><p>56:34 Closing remarks</p><br><p>#LeadingBeyondTheLab #ARTOTalent #Biotech #Immunology #AutoimmuneDisease #DrugDevelopment #AntibodyTherapeutics #RheumatoidArthritis #LifeSciences</p><hr><p style='color:grey; font-size:0.75em;'> Hosted on Acast. See <a style='color:grey;' target='_blank' rel='noopener noreferrer' href='https://acast.com/privacy'>acast.com/privacy</a> for more information.</p>

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<p>97% of our listeners don't realise they aren't followed, please double check, thank you!</p><br><p>The <strong>Leading Beyond The Lab </strong>Podcast is hosted by Lawrence Rose, one of the Directors at <strong>ARTO</strong>, a talent solutions agency specialising in leadership roles within the Life Sciences sector globally.</p><br><p>This podcast provides insightful discussions with industry experts, leaders and innovators, shaping the future in drug development and clinical devices. We talk with biotechnology and/or pharmaceutical executives, and find out from them their stories, personal career development and analyse their opinion on how to become successful in this space. We talk on a range of topics including soft skills, oncology, leadership, micromanagement, investment, cardiology, AI, dementia, addiction, hematology, dermatology, and much more.</p><br><p><strong>This podcast applies broadly to all types of connections in the Life Sciences Industry, and aims to educate and inspire those who want to excel in leadership.&nbsp;</strong></p><hr><p style='color:grey; font-size:0.75em;'> Hosted on Acast. See <a style='color:grey;' target='_blank' rel='noopener noreferrer' href='https://acast.com/privacy'>acast.com/privacy</a> for more information.</p>
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