Hosted by Mark Wade of TransPerfect Life Sciences, LifeSci Talks is an informal, informative conversation that focuses on a variety of themes and topics in the life sciences space. Featuring thought leaders and industry experts from different therapeutic areas and divisions, the discussions provide actionable takeaways and topical insights into current global challenges and opportunities.
The "Frankenstein Instrument" Problem Why Some PRO Measures Don't Fit Today's Patients
Are the COA Instruments we've relied on for decades still measuring what matters to patients today? In this episode, Mark Wade sits down with Kathrin Fischer PhD, Patient-Centered Outcome Strategy Lead at Boehringer Ingelheim and ISOQOL Director-at-Large Term: 2024 – 2027, to challenge some long-held assumptions in the COA space. They examine why some legacy instruments were built for a different era, what gets lost when items are stitched together from multiple measures, and whether computer adaptive testing could finally solve the patient burden problem. Kathrin also shares why cultural and regional bias in instrument design deserves more scrutiny, and where she'd point her magic wand if she could change one thing about the future of COA.
4 Aug 2026
Why eConsent Still Isn’t Standard in Clinical Trials—and What Could Change That
In this episode of LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, sits down with Edwin Cohen, Principal Consultant at C&Flow, to talk about eConsent adoption in clinical trials. They discuss the research behind why animated, electronic consent is better perceived by patients, the fragmented technology landscape sites have to navigate, the plain-language and health-literacy challenges baked into consent forms, and the timeline and budget pressures that keep eConsent from being standard practice. They also cover why pediatric and rare disease studies could be the fastest path to wider adoption, and how reconsent, an often-overlooked, recurring part of the process, is particularly well suited to going digital.
21 Jul 2026
Nothing Remains the Same: Why Measures Have to Evolve
In this episode of LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, sits down with RJ Wirth, CEO and Consulting Psychometrician at Vector Psychometric Group, to talk about why the measures we rely on are living things rather than fixed artifacts. The two discuss why keeping a rigorous measure is often harder than building it in the first place, walk through why studies still run on out-of-date versions and translations, and reflect on what happens when one of these unvalidated instruments is used in real-world applications. Tune in to hear why the same words on a page can mean something different a decade later, and how thoughtful measurement keeps instruments rigorous, relevant, and ready for whatever comes next, AI included.
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