Each episode is a deep dive on Mast Cell Activation Syndrome (MCAS) with a top physician, researcher or other expert who specializes in treating patients with MCAS. Hosted by Johns-Hopkins-trained world renowned specialist Tania Dempsey, MD, we take a practical approach to helping doctors and patients better manage MCAS. We cover the symptoms, testing, diagnosis, treatment, challenges, practical strategies, common comorbidities (e.g., POTS, hypermobility spectrum disorders, ME/CFS, autoimmunity, GI dysmotility), latest research findings and clinical pearls. These episodes are a monthly feature of The POTScast, presented by Standing Up to POTS, a non-profit dedicated to improving life for those with POTS and related chronic illness. Check out our full podcast — with other types of great episodes — at ThePOTScast.com.

Mast Cell Matters: Deep dives on MCAS with Tania Dempsey, MD - Presented by The POTScast
Claim This Podcastby Tania Dempsey, MD with Jill Brook, MA
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Podcast Overview
Each episode is a deep dive on Mast Cell Activation Syndrome (MCAS) with a top physician, researcher or other expert who specializes in treating patients with MCAS. Hosted by Johns-Hopkins-trained world renowned specialist Tania Dempsey, MD, we take a practical approach to helping doctors and patients better manage MCAS. We cover the symptoms, testing, diagnosis, treatment, challenges, practical strategies, common comorbidities (e.g., POTS, hypermobility spectrum disorders, ME/CFS, autoimmunity, GI dysmotility), latest research findings and clinical pearls. These episodes are a monthly feature of The POTScast, presented by Standing Up to POTS, a non-profit dedicated to improving life for those with POTS and related chronic illness. Check out our full podcast — with other types of great episodes — at ThePOTScast.com.
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Publishing Since
11/8/2023
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Recent Episodes

May 30, 2026
GLP-1s in MCAS with Dr. Tania Dempsey
Dr. Tania Dempsey shares her latest observations and recommendations on using GLP-1 medications for Mast Cell Activation Syndrome in this interview.

April 1, 2026
Cell membrane health and why it matters for MCAS and beyond with Dr. Melanie Stein and Dr. Tania Dempsey
Dr. Melanie Stein, ND is a licensed Naturopathic Physician in Portland, Oregon and a recognized leader in Cell Membrane Therapy for the treatment of complex and chronic illness. She specializes in restoring health at the cellular level—repairing and revitalizing cell membranes to improve energy production, enhance detoxification, and restore healthy communication between cells. In this episode, she and Dr. Dempsey discuss why cell membrane health is relevant to MCAS and many other chronic illnesses, testing and treatment approaches, their favorite in-office treatments, diet considerations and much more. Dr. Stein's clinic's website is here. Dr. Stein's book, Breaking Through Chronic Illness, is here on Amazon. Dr. Tania Dempsey's website is here. If you liked this episode, we hope you will click subscribe so that you don't miss an episode. If you are so moved, donations are accepted to help to support our production costs https://www.standinguptopots.org/donate Tell us what you think of The POTScast or send us your idea at info@standinguptopots.org! Find out more about Standing Up to POTS! Check us out on our Website: www.standinguptopots.org Facebook: https://www.facebook.com/standinguptopots/ Instagram: https://www.instagram.com/standinguptopots/ Twitter: https://twitter.com/POTSActivist Pintrest: https://www.pinterest.com/TheStandingUpToPOTS/ Medical Disclaimer: The information provided here is not intended to serve as professional medical advice, diagnosis, or treatment. If you have health related issues, please contact a qualified health professional to get the personalized assessment, advice, and treatment that you need. Standing Up to POTS will not be liable for any direct, indirect, or other damages arising from the use of this podcast.

March 1, 2026
More cutting edge treatments (part 2) with Dr. Tania Dempsey
Dr. Dempsey is always looking for new ways to help her complex patients. In this episode Dr. Dempsey discusses how she incorporates treatments with Methylene Blue, peptides, and the Nanovi breathing device. For each one she explains what it is, how it works, the risks and benefits, who is a good candidate, and more. More information about Dr. Tania Dempsey and her clinic can be found at https://drtaniadempsey.com/. If you liked this episode, we hope you will click subscribe so that you don't miss an episode. If you are so moved, donations are accepted to help to support our production costs https://www.standinguptopots.org/donate Tell us what you think of The POTScast or send us your idea at info@standinguptopots.org! Find out more about Standing Up to POTS! Check us out on our Website: www.standinguptopots.org Facebook: https://www.facebook.com/standinguptopots/ Instagram: https://www.instagram.com/standinguptopots/ Twitter: https://twitter.com/POTSActivist Pintrest: https://www.pinterest.com/TheStandingUpToPOTS/ Medical Disclaimer: The information provided here is not intended to serve as professional medical advice, diagnosis, or treatment. If you have health related issues, please contact a qualified health professional to get the personalized assessment, advice, and treatment that you need. Standing Up to POTS will not be liable for any direct, indirect, or other damages arising from the use of this podcast.
41 total episodes available with 1 transcripts
Recent guests on Mast Cell Matters: Deep dives on MCAS with Tania Dempsey, MD - Presented by The POTScast
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Tania Dempsey
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Dr Alexis Cutchins
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- What is Mast Cell Matters: Deep dives on MCAS with Tania Dempsey, MD - Presented by The POTScast?
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This podcast updates bi-weekly.
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