Joan Mannick on Rapamycin Longevity Series | Turning down mTOR to young levels may be good for aging
Dr Joan Mannick is one of the world’s leading rapamycin and mTOR researchers in the longevity field. Joan has a background in academic medicine and is currently CEO at her own company Tornado Therapeutics where they focus on developing the next generation of mTOR inhibitors. One of the company goals is to create a mTOR inhibitor which is better than Rapamycin. Throughout the years Joan has made important discoveries in humans when it comes to finding a connection between mTOR inhibition and improvement of the aging immune system. In this podcast we are going to talk about her research, drug development, mTOR, rapamycin, rapalogs and other interesting longevity topics.
Links
https://www.tornado-tx.com (Tornado Therapeutics)
Joan's LinkedIn (https://www.linkedin.com/in/joan-mannick-8089a614)
Joan’s research publications (https://pubmed.ncbi.nlm.nih.gov/?term=Mannick+JB)
Big thanks to TimePie for the research help for this episode (https://www.youtube.com/@timepie7959)
Rapamycin resources
Rapamycin.news (https://www.rapamycin.news)
Rapamycin Facebook group (https://www.facebook.com/groups/rapamycin)
Rapamycin Reddit group (https://www.reddit.com/r/Rapamycin)
Connect with Krister on:
Twitter (https://twitter.com/KristerKauppi)
LinkedIn (https://www.linkedin.com/in/krister-kauppi)
Instagram (https://www.instagram.com/longevity.lifestyle.hacker)
Disclaimer: The podcast is for general information and educational purposes only and is not medical advice for you or others. The use of information and materials linked to the podcast is at the users own risk. Always consult your physician with anything you do regarding your health or medical condition.
17 Oct 2023
Brian Kennedy on Rapamycin Master Series | Aging is the biggest risk factor for age-related diseases
Professor Brian Kennedy from the National University of Singapore is one of the world's leading researchers in the longevity field and has done longevity research for more than two decades. He is active in many different longevity companies and has been the President and CEO at Buck Institute for Research on Aging. Throughout the years he has made many different important and revolutionary longevity discoveries. Currently he is also one of the persons who is trying to move the longevity forward in a much efficient and faster way. This work he is doing in Singapore where he is leading a huge longevity research project. This unique project is something we are going to talk about in the podcast. We will also talk about his research on Rapamycin and other interesting longevity topics.
Links
The centre for Healthy Longevity at the National University of Singapore (https://coe.nuhs.edu.sg/Centre-for-Healthy-Longevity/Pages/default.aspx)
Healthy Longevity webinars on Youtube (https://www.youtube.com/@NUSYLLSoM)
Brian's research publications (https://pubmed.ncbi.nlm.nih.gov/?term=Kennedy+BK)
Brian's Twitter (https://www.linkedin.com/in/brian-kennedy-69777318)
Brian's LinkedIn (https://twitter.com/BKennedy_aging)
Rapamycin resources
Rapamycin.news (https://www.rapamycin.news)
Rapamycin Facebook group (https://www.facebook.com/groups/rapamycin)
Rapamycin Reddit group (https://www.reddit.com/r/Rapamycin)
Connect with Krister on:
Twitter (https://twitter.com/KristerKauppi)
LinkedIn (https://www.linkedin.com/in/krister-kauppi)
Instagram (https://www.instagram.com/longevity.lifestyle.hacker)
Disclaimer: The podcast is for general information and educational purposes only and is not medical advice for you or others. The use of information and materials linked to the podcast is at the users own risk. Always consult your physician with anything you do regarding your health or medical condition.
22 Aug 2023
Mikhail Blagosklonny on Rapamycin Longevity Series | mTOR drives age-related diseases
The world's leading Rapamycin researcher Mikhail Blagosklonny has a long background in cancer research and one important discovery he made around 2000 was that Rapamycin slowed down senescent cancer cells in different ways. After that step by step his interest in the longevity field increased and he developed the very interesting hyperfunction theory of aging. He has made a huge contribution in moving the Rapamycin longevity field forward and his research papers have impacted many people. For example, the Rapamycin physician Alan Green who thanks to these papers took the decision in 2017 to start prescribing Rapamycin off label. Today Alan Green has the biggest clinical experience in the area with more than 1200 patients. A lot of other physicians have after that also taken these steps and one of those are for example physician Peter Attia.
Links
Mikhail's research publications (https://pubmed.ncbi.nlm.nih.gov/?term=blagosklonny+m)
Mikhail's twitter (https://twitter.com/Blagosklonny)
Homepage (https://www.mikhailblagosklonny.com)
Rapamycin resources
Rapamycin.news (https://www.rapamycin.news)
Rapamycin Facebook group (https://www.facebook.com/groups/rapamycin)
Rapamycin Reddit group (https://www.reddit.com/r/Rapamycin)
Connect with Krister on:
Twitter (https://twitter.com/KristerKauppi)
LinkedIn (https://www.linkedin.com/in/krister-kauppi)
Instagram (https://www.instagram.com/longevity.lifestyle.hacker)
Disclaimer: The podcast is for general information and educational purposes only and is not medical advice for you or others. The use of information and materials linked to the podcast is at the users own risk. Always consult your physician with anything you do regarding your health or medical condition.
11 Jul 2023
Brad Stanfield on Rapamycin Longevity Series | Rapamycin, mTOR and the importance of muscle in life
Dr Brad Stanfield works as a medical doctor in New Zealand and beside his work in primary-care he has his own Youtube channel, in which he goes through the latest research and clinical guidelines on preventative medicine and longevity. In today’s podcast we are going to talk about Brad’s upcoming Rapamycin trial, the importance of muscle when we get older, sarcopenia and lots of other interesting longevity topics.
Links
Brad Stanfield's Youtube (https://www.youtube.com/@DrBradStanfield)
Donate to Brad's Rapamycin clinical trial (https://drstanfield.com/pages/ongoing-clinical-studies)
Brad's MicroVitamin supplement (https://drstanfield.com/products/microvitamin)
Brad's twitter (https://twitter.com/BradStanfieldMD)
Rapamycin resources
Rapamycin.news (https://www.rapamycin.news)
Rapamycin Facebook group (https://www.facebook.com/groups/rapamycin)
Rapamycin Reddit group (https://www.reddit.com/r/Rapamycin)
Connect with Krister on
Twitter (https://twitter.com/KristerKauppi)
LinkedIn (https://www.linkedin.com/in/krister-kauppi)
Instagram (https://www.instagram.com/longevity.lifestyle.hacker)
Disclaimer: The podcast is for general information and educational purposes only and is not medical advice for you or others. The use of information and materials linked to the podcast is at the users own risk. Always consult your physician with anything you do regarding your health or medical condition.
14 Jun 2023
Pankaj Kapahi on Rapamycin Longevity Series | There is no one size longevity intervention that fits all
Professor Pankaj Kapahi has his own lab at the Buck Institute for Research on Aging. His research for two decades has been focusing on things such as dietary restriction, fasting, rapamycin, nutrition and longevity. Pankaj was one of the pioneer researchers who discovered in the beginning of 2000 that genetic inhibition of mTOR led to life extension in flies. In this podcast we are going to talk about that discovery, Rapamycin, calorie restriction and other interesting longevity topics.
Links
Kapahi's Lab at Buck Institute (https://www.buckinstitute.org/lab/kapahi-lab)
Juvify and GLYLO (https://juvifyhealth.com)
Pankaj's twitter (https://twitter.com/kapahi_pankaj)
Rapamycin resources
Rapamycin.news (https://www.rapamycin.news)
Rapamycin Facebook group (https://www.facebook.com/groups/rapamycin)
Rapamycin Reddit group (https://www.reddit.com/r/Rapamycin)
Connect with Krister on:
Twitter (https://twitter.com/KristerKauppi)
LinkedIn (https://www.linkedin.com/in/krister-kauppi)
Instagram (https://www.instagram.com/longevity.lifestyle.hacker)
Disclaimer: The podcast is for general information and educational purposes only and is not medical advice for you or others. The use of information and materials linked to the podcast is at the users own risk. Always consult your physician with anything you do regarding your health or medical condition.
15 May 2023
Matt Kaeberlein on Rapamycin Longevity Series | Lessons learned from two decades of Rapamycin research
Professor Matt Kaeberlein from the University of Washington is one of the world's leading researchers in the Rapamycin field. He has done Rapamycin research on multiple species for two decades. Everything from yeasts, worms, mice and now also dogs and humans. Matt has made a big contribution to the longevity field and in this podcast he will share the knowledge he has acquired in the field.
Links
The Dog Aging Project (possible to still apply) (https://dogagingproject.org)
Ora Biomedical (https://orabiomedical.com)
Optispan (https://optispan.life)
Matt's twitter (https://twitter.com/mkaeberlein)
Rapamycin resources
Rapamycin.news (https://www.rapamycin.news)
Rapamycin Facebook group (https://www.facebook.com/groups/rapamycin)
Rapamycin Reddit group (https://www.reddit.com/r/Rapamycin)
Connect with Krister on
Twitter (https://twitter.com/KristerKauppi)
LinkedIn (https://www.linkedin.com/in/krister-kauppi)
Instagram (https://www.instagram.com/longevity.lifestyle.hacker)
Disclaimer: The podcast is for general information and educational purposes only and is not medical advice for you or others. The use of information and materials linked to the podcast is at the users own risk. Always consult your physician with anything you do regarding your health or medical condition.
11 Apr 2023
Alan Green on Rapamycin Longevity Series | Lessons learned from over 1200 patients
Dr Alan Green has his own medical practice in New York which focuses on longevity. He is a Rapamycin pioneer and one of the important longevity leaders who has made a big contribution to the longevity field and especially regarding the compound Rapamycin. Today he has clinical experience of more than 1200 patients who take Rapamycin and in this podcast he will share the knowledge he has acquired in the field.
Contact information for Dr Alan Green's medical practice can be found here
https://rapamycintherapy.com (https://rapamycintherapy.com)
Rapamycin resources
Rapamycin.news (https://www.rapamycin.news)
Rapamycin Facebook group (https://www.facebook.com/groups/rapamycin)
Rapamycin Reddit group (https://www.reddit.com/r/Rapamycin)
Connect with Krister on
Twitter (https://twitter.com/KristerKauppi)
LinkedIn (https://www.linkedin.com/in/krister-kauppi)
Instagram (https://www.instagram.com/longevity.lifestyle.hacker)
Disclaimer: The podcast is for general information and educational purposes only and is not medical advice for you or others. The use of information and materials linked to the podcast is at the users own risk. Always consult your physician with anything you do regarding your health or medical condition.
15 Mar 2023
Ross Pelton on Rapamycin Longevity Series | How it all began
Ross Pelton has a background as a pharmacist and is an author of 12 books in the health field. In this podcast we are going to talk about his recent published book "Rapamycin, mTOR, Autophagy & Treating mTOR Syndrome". The purpose of this podcast is to increase our knowledge about Rapamycin and it's longevity effects.
His book can be found on https://www.lifeextension.com/rapa (https://www.lifeextension.com/rapa)
Or call (866) 598-6747 24 hours a day to order the book and get a free 6-month subscription to Life Extension magazine
Ross Pelton's homepage https://www.naturalpharmacist.net (https://www.naturalpharmacist.net)
Links from the podcast
- The Dog Aging Project
https://dogagingproject.org (https://dogagingproject.org)
- Ross Pelton's paper "The Microbiome Theory of Aging"
http://imjournal.com/oa/index.html?fid=Microbiome_Theory_of_Aging (http://imjournal.com/oa/index.html?fid=Microbiome_Theory_of_Aging)
- Free book about Dr. Ohhira's Probiotics & Postbiotic Metabolites
https://naturalpharmacist.net/ohhirabook (https://naturalpharmacist.net/ohhirabook)
Connect with Krister on
Twitter (https://twitter.com/KristerKauppi)
LinkedIn (https://www.linkedin.com/in/krister-kauppi)
Instagram (https://www.instagram.com/longevity.lifestyle.hacker)
Disclaimer: The podcast is for general information and educational purposes only and is not medical advice for you or others. The use of information and materials linked to the podcast is at the users own risk. Always consult your physician with anything you do regarding your health or medical condition.
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