Medium Yield

About Medium Yield

A podcast about arcane medical history and facts with an Australian bent. A celebration of the niche and miscellaneous. Mostly low yield, rarely high yield - on average: medium yield.

Publisher

Jake Leonard

Category

health & fitness

Language

en

Explicit

No

First episode

15 Aug 2023

Latest episode

21 Feb 2025

Latest episodes

8 episodes in the feed.

1. 

   21 Feb 2025

   08 - Thalidomide's long shadow

   Prior to 1961 drugs were not stringently tested before being introduced to the Australian market. The prevailing view in obstetric care was that medications that were non-toxic to the mother were non-toxic to the developing fetus. This illusion was dramatically and irreversibly shattered in 1961 when Sydney obstetrician Dr William McBride raised the alarm that babies exposed to thalidomide were being born with significant birth defects. The thalidomide tragedy would go on to have seismi...

2. 

   7 Nov 2024

   07 - Everyone's favourite hold music

   You might not know the name, but you have heard it countless times - and you either love or loathe Opus Number 1Opus Number 1 is copyright Tim Carleton and Darrick Deel. Parts reproduced here under fair dealing exceptions of the Copyright Act 1968.References6Sense "Cisco VoIP" accessed November 2024Buckley, Sean 2018 "Cisco, Avaya retain dominant PBX market share, but segment drops 8% on delayed spending, cloud migration, says analyst" Fierce Network accessed November 2024Corbett, Sara 2014 "...

3. 

   16 Feb 2024

   06 - Liquorice induced pseudohyperaldosteronism

   Just like a fistful of black jellybeans from the chemist, "liquorice induced pseudohyperaldosteronism" is a challenging mouthful. Just how does liquorice cause high blood pressure and low potassium? References Allcock E, J Cowdery 2015 "Hypertension induced by liquorice tea (https://doi.org/10.1136%2Fbcr-2015-209926)" BMJ Case Reports Martini N 2020 “Liquorice (https://doi.org/10.1071/HC15958)” Journal of Primary Health Care 12(4) 397-398 Mérillon, J-M & KG Ramawat 2018, “The Pharmacological Activities of Glycyrrhizinic Acid (“Glycyrrhizin”) and Glycyrrhetinic Acid (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7123798/)” pp. 245-261 in Sweeteners, Springer Quinkler M, PM Stewart 2003 “Hypertension and the Cortisol-Cortisone Shuttle (https://academic.oup.com/jcem/article/88/6/2384/2845128)” The Journal of Clinical Endocrinology & Metabolism Vol 88 Iss 6 pp 2384-2392 Schonwald S 2022 “Licorice poisoning treatment and management (https://emedicine.medscape.com/article/817578-treatment#d1?form=fpf)” Medscape Varma R, CN Ross 2017 "Liquorice: a root cause of secondary hypertension (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298563/)" JSRM Open 8(2) Wikipedia "Liquorice (https://en.wikipedia.org/wiki/Liquorice)"

4. 

   26 Oct 2023

   05 - Humans are getting colder

   Carl Wunderlich's seminal 1868 work "The Course of Temperature in Disease" defined the average human body temperature as 37 degrees celsius, a number that is still frequently quoted today. But the question of the average body temperature is far from settled. Could it be that it is changing with time? Music: Variatio 3 a 1 Clav. Canone all Unisuono Music by JS Bach, played by Kimiko Ishizaka (https://kimikoishizaka.bandcamp.com) for the Open Goldberg Variations project References: Ley C et al 2023 “Defining usual oral temperature ranges in outpatients using an unsupervised learning algorithm” JAMA https://doi.org/10.1001/jamainternmed.2023.4291 (https://doi.org/10.1001/jamainternmed.2023.4291) Mackowiak, P & Woden, G 1994 “Carl Reinhold August Wunderlich and the Evolution of Clinical Thermometry” Clinical Infectious Diseases https://www.jstor.org/stable/4457716 (https://www.jstor.org/stable/4457716) Protsiv M et al 2020 “Decreasing human body temperature in the United States since the Industrial Revolution” eLife https://doi.org/10.7554/eLife.49555 (https://doi.org/10.7554/eLife.49555) Speakman et al JR 2023 “Total daily energy expenditure has declined over the last 3 decades due to declining basal expenditure not reduced activity expenditure” Nature Metabolism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445668/ (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445668/) Sund-Levander et al 2002 “Normal oral, rectal, tympanic and axillary body temperature in adult men and women: a systematic literature review” Scandinavian Journal of Caring Sciences https://doi.org/10.1046/j.1471-6712.2002.00069.x (https://doi.org/10.1046/j.1471-6712.2002.00069.x) Wikipedia “Doubly labeled water” https://en.wikipedia.org/wiki/Doubly_labeled_water (https://en.wikipedia.org/wiki/Doubly_labeled_water) Wikipedia “Medical Thermometer” https://en.wikipedia.org/wiki/Medical_thermometer (https://en.wikipedia.org/wiki/Medical_thermometer)

5. 

   8 Oct 2023

   04 - The history of French, needle and suture gauges

   Join me on a truly low yield romp through the history of measuring medical equipment, spanning three countries and three centuries. References: Iverson 1987 “J.-F.-B. Charriere: The Man Behind the ‘French’ Gauge’”, The Journal of Emergency Medicine Vol 5 pp. 545-548 Iverson 1987 "The origins of the gauge system for medical equipment", The Journal of Emergency Medicine Vol 5 pp. 45-48 Muffly, T et al. 2011 “The history and evolution of sutures in pelvic surgery (https://doi.org/10.1258%2Fjrsm.2010.100243)” Journal of the Royal Society of Medicine, v 104(3) pp 107-112 Pöll J.S 2002 "The story of the gauge ( https://doi.org/10.1046/j.1365-2044.1999.00895.x)" Anaesthesia Vol 54, Issue 6, pp. 519-623 Wikipedia: Guillaume Dupuytren (https://en.wikipedia.org/wiki/Guillaume_Dupuytren) History of the Metric System (https://en.wikipedia.org/wiki/History_of_the_metric_system) Industrial Revolution (https://en.wikipedia.org/wiki/Industrial_Revolution) Surgical Suture (https://en.wikipedia.org/wiki/Surgical_suture) Music: "La Marseillaise (https://en.wikipedia.org/wiki/File:La_Marseillaise.ogg)" composed by Claude Joseph Rouget de Lisle Recorded by the United States Navy Band Public Domain "Rule, Britannia (https://en.wikipedia.org/wiki/File:Rule,_Britannia.ogg)" composed by James Thomson (lyrics) and Thomas Anne (music). Sung by Albert Farrington 1914 for Edison Records "Star Spangled Banner (https://en.wikipedia.org/wiki/File:Star_Spangled_Banner_instrumental.ogg)" composed by John Stafford Smith Recorded by the United States Navy Band Public Domain

6. 

   25 Sept 2023

   03 - Beriberi on Christmas Island

   Christmas Island, in the Indian Ocean, is remote and difficult to access by sea. The discovery of phosphate in the late 19th century changed its fortunes. In 1899 workers arrived to tame the island. Soon after they arrived, an ancient disease with an unknown cause and no known cure joined them - beriberi. References: Arts, Nicolass JM et al 2017 “Korsakoff’s syndrome: a critical review” Neuropsychiatric Disease and Treatment  vol 13 pp 2875-2890 https://doi.org/10.2147/NDT.S130078 (https://doi.org/10.2147/NDT.S130078) Blevins, Melissa 2014 “Why are vitamins labeled A, B (and all the sub B’s), C, etc.?”, Today I Found Out, http://www.todayifoundout.com/index.php/2014/04/vitamins-labeled-b-sub-bs-c-etc/ (http://www.todayifoundout.com/index.php/2014/04/vitamins-labeled-b-sub-bs-c-etc/) Carpenter, Kenneth J. 2005 "Beriberi, White Rice, and Vitamin B: A Disease, a Cause, and a Cure", University of California Press Hunt, John 2011 "Suffering through strength: The men who made Christmas Island", Blue Star Print ACT McCutechon, Peter 24 June 2021 "Christmas Island future uncertain as phosphate mine starts to wind down", ABC News, https://www.abc.net.au/news/2021-06-24/christmas-island-future-uncertain-as-phosphate-mine-winds-down/100231824 (https://www.abc.net.au/news/2021-06-24/christmas-island-future-uncertain-as-phosphate-mine-winds-down/100231824) Mozaffarian, Dariush et al 2018 “History of modern nutrition science—implications for current research, dietary guidelines, and food policy” BMJ https://doi.org/10.1136/bmj.k2392 (https://doi.org/10.1136/bmj.k2392) Sinha, Shirshendu et al 2019 “Wernicke Encephalopathy - Clinical Pearls” Mayo Clinical Proceedings Vol 94 Iss 6 https://doi.org/10.1016/j.mayocp.2019.02.018 (https://doi.org/10.1016/j.mayocp.2019.02.018) Wikipedia "Christmas Island" https://en.wikipedia.org/wiki/Christmas_Island#Demographics (https://en.wikipedia.org/wiki/Christmas_Island#Demographics) Wilson, Robert Beaumont 2020 “Pathophysiology, prevention and treatment of beriberi after gastric surgery” Nutrition Reviews, Volume 78, Issue 12, pp 1015-1029 https://doi.org/10.1093/nutrit/nuaa004 (https://doi.org/10.1093/nutrit/nuaa004) Yeoh, Fran "The old hospital and the scourge of beriberi", Christmas Island Archives, https://christmasislandarchives.com/old-hospital/ (https://christmasislandarchives.com/old-hospital/)

7. 

   28 Aug 2023

   02 - Snakes on a staff

   The twisty history of the Rod of Asclepius and the Caduceus as symbols of medicine. References: Wikipedia. Truly so much Wikipedia. Particularly: Asclepius https://en.wikipedia.org/wiki/Asclepius (https://en.wikipedia.org/wiki/Asclepius) Aesculapian Snake https://en.wikipedia.org/wiki/Aesculapian_snake (https://en.wikipedia.org/wiki/Aesculapian_snake) Caduceus as a symbol of medicine https://en.wikipedia.org/wiki/Caduceus_as_a_symbol_of_medicine (https://en.wikipedia.org/wiki/Caduceus_as_a_symbol_of_medicine) Greek Mythology https://en.wikipedia.org/wiki/Greek_mythology (https://en.wikipedia.org/wiki/Greek_mythology) Hermes https://en.wikipedia.org/wiki/Hermes (https://en.wikipedia.org/wiki/Hermes) Imhotep https://en.wikipedia.org/wiki/Imhotep (https://en.wikipedia.org/wiki/Imhotep) Panacea https://en.wikipedia.org/wiki/Panacea (https://en.wikipedia.org/wiki/Panacea) Rod of Asclepius https://en.wikipedia.org/wiki/Rod_of_Asclepius (https://en.wikipedia.org/wiki/Rod_of_Asclepius) RAAF Medical Uniforms: http://australianmilitarymedicalcollective.weebly.com/raaf-uniform-development.html (http://australianmilitarymedicalcollective.weebly.com/raaf-uniform-development.html) RAAMC Customs https://www.raamc.org.au/web/index.php?History:Customs (https://www.raamc.org.au/web/index.php?History:Customs) Westphalen, Neil 2018, “A History of Australian Navy Health Sailor Uniforms and Ranks (part 3)” Journal of Military and Veteran's Health Vol 26 No 4 https://jmvh.org/article/a-history-of-australian-navy-health-sailor-uniforms-and-ranks-part-3/ (https://jmvh.org/article/a-history-of-australian-navy-health-sailor-uniforms-and-ranks-part-3/)

8. 

   15 Aug 2023

   01 - Scorpion Sting Pancreatitis

   By far the most easily remembered cause of pancreatitis is scorpion stings. But how likely are you to see sting induced pancreatitis in Australia? References: Albuquerue et al 2018 "Acute kidney injury and pancreatitis due to scorpion sting: case report and literature review (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029862/)", Rev Inst Med Trop Sau Pauloa Carter, Murray 2020, "Marbled Scorpion (https://australian.museum/learn/animals/spiders/marbled-scorpion-lychas-marmoreus/)", Australian Museum Webpage Emergency Care Institute NSW 2023 "Bites and Stings (https://aci.health.nsw.gov.au/networks/eci/clinical/clinical-tools/bites-and-stings#heading5)" Fletcher et al 2010 "Vesicle-associated Membrane Protein (VAMP) Cleavage by a New Metalloprotease from the Brazilian Scorpion Tityus serrulatus (https://www.jbc.org/article/S0021-9258(19)58728-2/fulltext)", Journal of Biological Chemistry Kallel et al 2016, "Acute Necrotizing Pancreatitis after Tityus obscurus Scorpion Envenomation in French Guiana (https://www.longdom.org/open-access/acute-necrotizing-pancreatitis-after-emtityus-obscurusem-scorpion-envenomation-in--french-guiana-51354.html)", Journal of Clinical Toxicology Nesvaderani et al 2015, "Acute pancreatitis: update on management (https://www.mja.com.au/journal/2015/202/8/acute-pancreatitis-update-management)", Medical Journal of Australia Nesvaderani et al 2015, "Epidemiology, aetiology and outcomes of acute pancreatitis: A retrospective cohort study (https://www.sciencedirect.com/science/article/pii/S1743919115010730?via%3Dihub)", International Journal of Surgery Sofer et al 1991 "Acute pancreatitis in children following envenomation by the yellow scorpion Leiurus quinquestriatus (https://pubmed.ncbi.nlm.nih.gov/2028471/)", Toxicon

Reach and audience

Public platform figures. Ratings count people who left a rating, not total listeners.

Spotify

5.0 / 5

7 ratings

Podcast Authority Score: 16 / 100

A composite of feed quality, social presence, YouTube performance and engagement. Read the methodology.

Quality

8

Social presence

0

YouTube

0

Engagement

60

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Guest appearances

Books guests

Based on episode analysis; this does not confirm that the show is currently accepting guests.