Listen to Medscape InDiscussion: Myasthenia Gravis, a podcast series where thought leaders and clinical experts share their diverse insights and practical ideas for optimizing patient care. Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/989800). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Managing Myasthenia Gravis in Primary Care: Best Practices
Drs Nicholas Silvestri and Michael Hehir discuss best practices for primary care physicians who see patients with myasthenia gravis.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/990463). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
New and Emerging Treatments for Myasthenia Gravis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407383/
Meningococcal Vaccination: Recommendations of the Advisory Committee on Immunization Practices, United States, 2020 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527029/
Myasthenia Gravis With Elderly Onset at Advanced Age https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991148/
Myasthenia Gravis, Respiratory Function, and Respiratory Tract Disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10132430/
Myasthenic Crisis https://pubmed.ncbi.nlm.nih.gov/37114503/
Telemedicine Visits in Myasthenia Gravis: Expert Guidance and the Myasthenia Gravis Core Exam (MG-CE) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057373/
MGFA Partners in MG Care Program https://myasthenia.org/Professionals/MGFA-Partners-in-MG-Care
MGFA List of Cautionary Drugs https://myasthenia.org/Portals/0/Cautionary%20Drugs.pdf
21 Sept 2023
Myasthenia Gravis: Exercise and Lifestyle Considerations
Drs Nicholas Silvestri and Kelly Gwathmey discuss how exercise and other modifiable lifestyle factors can influence how patients experience the burden of myasthenia gravis.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/990462). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Evidence-based Practice in Rehabilitation of Myasthenia Gravis. A Systematic Review of the Literature https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739309/
Drugs That Induce or Cause Deterioration of Myasthenia Gravis: An Update https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038781/
The Humanistic Burden of Myasthenia Gravis: A Systematic Literature Review https://pubmed.ncbi.nlm.nih.gov/35486970/
Outcome Measures in Clinical Trials of Patients With Myasthenia Gravis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793650/
23 Aug 2023
Myasthenia Gravis: Who Really Benefits From Thymectomy?
Drs Nicholas Silvestri and Gil Wolfe get right to the point about when and why thymectomy may be considered as an evidence-based option for treatment of myasthenia gravis.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/990461). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Long-term Effect of Thymectomy Plus Prednisone Versus Prednisone Alone in Patients With Non-thymomatous Myasthenia Gravis: 2-year Extension of the MGTX Randomised Trial https://pubmed.ncbi.nlm.nih.gov/30692052/
Randomized Trial of Thymectomy in Myasthenia Gravis https://pubmed.ncbi.nlm.nih.gov/27509100/
The Short and Long-term Effects of Open vs Minimally Invasive Thymectomy in Myasthenia Gravis Patients: A Systematic Review and Meta-analysis https://pubmed.ncbi.nlm.nih.gov/36539629/
Prognostic Factors for Conversion to Generalization in Ocular Myasthenia Gravis https://pubmed.ncbi.nlm.nih.gov/34106649/
Development of a Model Care Pathway for Myasthenia Gravis https://pubmed.ncbi.nlm.nih.gov/34770107/
Drugs That Induce or Cause Deterioration of Myasthenia Gravis: An Update https://pubmed.ncbi.nlm.nih.gov/33917535/
25 Jul 2023
Tools for More Personalized Myasthenia Gravis Care
Drs Nicholas Silvestri and James "Chip" Howard discuss newer and novel myasthenia gravis tools to personalize treatment, including complement inhibitors, FcRn antagonists, biomarkers, and more.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/990460). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Safety and Efficacy of Eculizumab in Refractory Generalized Myasthenia Gravis (REGAIN Study) https://clinicaltrials.gov/ct2/show/NCT01997229
Safety and Efficacy of Eculizumab in Anti-acetylcholine Receptor Antibody-positive Refractory Generalised Myasthenia Gravis (REGAIN): A Phase 3, Randomised, Double-blind, Placebo-controlled, Multicentre Study https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(17)30369-1/fulltext
ULTOMIRIS® (Ravulizumab-cwvz) Approved in the US for Adults With Generalized Myasthenia Gravis https://www.astrazeneca-us.com/media/press-releases/2022/ultomiris-approved-in-the-us-for-adults-with-generalized-myasthenia-gravis.html
UCB Announces US FDA Acceptance of New Drug Application and EMA MAA Validation for Zilucoplan for the Treatment of Generalized Myasthenia Gravis in Adult Patients https://www.prnewswire.com/news-releases/ucb-announces-us-fda-acceptance-of-new-drug-application-and-ema-maa-validation-for-zilucoplan-for-the-treatment-of-generalized-myasthenia-gravis-in-adult-patients-301676223.html
Zilucoplan: An Investigational Complement C5 Inhibitor for the Treatment of Acetylcholine Receptor Autoantibody–positive Generalized Myasthenia Gravis https://www.tandfonline.com/doi/full/10.1080/13543784.2021.1897567
22 Jun 2023
Treating Myasthenia Gravis? Don't Stop at Pyridostigmine
Drs Nicholas Silvestri and Neelam Goyal lay out pathways for successful routine treatment of myasthenia gravis.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/990458). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Adverse Side Effects Associated With Corticosteroid Therapy: A Study in 39 Patients With Generalized Myasthenia Gravis https://pubmed.ncbi.nlm.nih.gov/34707081/
The History of Acetylcholinesterase Inhibitors in the Treatment of Myasthenia Gravis https://pubmed.ncbi.nlm.nih.gov/32918950/
FcRn Inhibitors: A Novel Option for the Treatment of Myasthenia Gravis https://pubmed.ncbi.nlm.nih.gov/36751773/
Ravulizumab: A Review in Generalised Myasthenia Gravis https://pubmed.ncbi.nlm.nih.gov/37166620/
Safety and Efficacy of Eculizumab in Anti-acetylcholine Receptor Antibody-positive Refractory Generalised Myasthenia Gravis (REGAIN): A Phase 3, Randomised, Double-blind, Placebo-controlled, Multicentre Study https://pubmed.ncbi.nlm.nih.gov/29066163/
22 Jun 2023
Myasthenia Gravis: Which Test Is Best? When and Why?
Drs Nicholas Silvestri and Carolina Barnett-Tapia discuss what you need to know about immunopathogenesis and diagnosis for this relatively rare condition.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/989800). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Myasthenia Gravis: Epidemiology, Pathophysiology and Clinical Manifestations https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8196750/
Complement Inhibitor Therapy for Myasthenia Gravis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283905/
Spotlight on MuSK Positive Myasthenia Gravis: Clinical Characteristics, Treatment and Outcomes https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895578/
A Radioimmunoassay for the Quantitative Evaluation of Anti-human Acetylcholine Receptor Antibodies in Myasthenia Gravis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1541026/
Reach and audience
Public platform figures. Ratings count people who left a rating, not total listeners.
Apple Podcasts (US)
4.8 / 5
8 ratings
Contact Medscape InDiscussion: Myasthenia Gravis
Guest appearances
Books guests
Based on episode analysis; this does not confirm that the show is currently accepting guests.
Host of Medscape InDiscussion: Myasthenia Gravis?
Claim your podcast to manage its listing and keep your show details accurate.
Pod Engine is an independent podcast discovery and analytics service and is not affiliated with or endorsed by this podcast. Artwork and show content belong to their owners. Full legal notice.
Explore this show Podcast research with Pod Engine
