Dr. Robert Melillo is a world renowned expert in adult and childhood developmental neurological conditions, functional neuroimmunology. He is joined by Dr. Peter Scire, a colleague and protégé of Dr Melillo, and also an expert in Functional Medicine. This show is focused on bringing the most cutting edge scientific and clinical information on many different common issues that are all related to brain developmental issues.
In the latest episode, Dr. Melillo and Dr. Scire discuss why parents more than ever don't know who to believe. They discuss how social media is adding to that distrust and confusion while also discussing how the different approaches to treating neurobehavioral disorders of childhood are so fragmented. During their conversation the doctors will touch on the following.
You'll hear them discuss:
Breaking things down in terms of left and right brain
The Echo chamber that is the left hemisphere.
This feels right to me. How the right brain makes decisions.
The importance of integration in the brain.
The story of the Blind Men and the Elephant.
What makes the Melillo Method different than traditional therapies?
Why is there such a gap in immunology training for practitioners?
Emergence of systems neuroimmunology.
The importance of a physical examination and functional measurements.
Multiple systems involvement can only mean you address the brain first.
All those different diagnoses mean there is a brain imbalance.
Stories of how young adults have been helped by Melillo Method.
Research outcomes behind the Melillo Method.
Step 1 in learning about the Melillo Method.
31 Mar 2025
How does your brain generate goals and habits?
In the first episode of 2025, Dr. Melillo and Dr. Scire discuss habit formation, goal setting and manifestation from a neurological perspective. Throughout their conversation they explain how different parts of the right and left brain contribute to these functions, especially the prefrontal cortex and the basal ganglia. Dr. Melillo shares how to apply the Goal, Purpose, Action (GPA) program he wrote about in the Reconnected Kids for yourself and child.
26 Feb 2025
Where in the brain do OCD, Tics, Stims and Anxiety come from?
So many children are currently being diagnosed with Anxiety, OCD, Motor tics and other
hyperkinetic behaviors. In this new episode Dr. Melillo and Dr. Scire expand on prior
conversations about the right and left hemisphere’s specialization. They discuss specific
pathways within each hemisphere and how they are responsible for these various
symptoms.
Key Points:
The Platform of Behavior: Approach and Avoidance
Review of Right and Left hemisphere Emotions
Early Development of the Right Hemisphere
Review of Basal Ganglia Pathways and how they influence human motor,
cognitive and emotional functions.
Discussion of the 5 major frontal-striatal brain circuitry
Right and left hemisphere personalities
Case Review of teenager with motor tics and hyperactive immune responses.
23 Jan 2025
What makes the human brain grow?
Over the past several episodes, Dr. Melillo and Dr. Scire have discussed the
developmental blueprint of the human brain. In this episode, they elaborated on the
early development of the brain during gestation, the first several years of life and how
these various stages of development allow the brain to build the complex networks that
operate social engagement, emotional regulation, executive functions and human
consciousness.
Key Topics:
The right brain’s role in attachment, social engagement, nonverbal
communication and emotional regulation.
Explanation of the development of the autonomic nervous system in the first year
of life.
Why is movement during early childhood so critical for the brain?
How does the brain modulate the development of the gastrointestinal system?
What are the early signs of alterations in the developmental brain blueprint?
How does bipedalism drive the emergent properties of the human brain?
Discuss the role of the vestibular system in movement and cognition.
The role of hemispheric function on the autonomic nervous system and the
immune system.
9 Dec 2024
Change doesn't always look Good
Dr. Melillo and Dr. Scire reveal how the Melillo Method's brain-stimulating protocols can produce seemingly negative emotional, behavioral, and metabolic changes, but ultimately lead to positive developmental outcomes.
11 Nov 2024
How exactly does the Melillo Method change the brain?
One of the first questions parents often ask Dr. Melillo is how does the Melillo Method approach change my child's brain? In this episode of Everything Brain, Dr. Melillo explains exactly how his approach can change the brain by harnessing the principles of neuroplasticity to improve the functional capabilities of the brain of a child with a developmental delay. Dr. Melillo and Dr. Scire discusses how they determine what areas of the brain are underdeveloped in the brain and then how they choose which Melillo Method therapies they will use to stimulate the brain to promote neuroplasticity within those areas and the entire brain.
29 Oct 2024
What does the science say about Brain Asymmetry?
Over the past few decades pop culture has created numerous lists to describe the functions of the right and left hemispheres. However, many of these lists have created more misconceptions regarding the 2 hemispheres than clarity. During this episode of Everything Brain, Dr. Melillo and Dr. Scire tackle these misconceptions by providing an in-depth perspective on brain laterality research over the past several decades while also discussing several books that have been written on brain lateralization by the acclaimed psychiatrist Dr. Iain McGilchrist.
16 Oct 2024
What makes the new edition of Disconnected Kids Different?
Welcome back to the Melillo Method Podcast, it’s now been several weeks since the 3rd Edition of the Disconnected Kids book was released. The excitement surrounding this edition is at an all-time high. During this episode Dr. Melillo and Dr. Scire discuss the new chapters on primitive reflexes that explain the new research conducted by Dr. Melillo’s research team as well how impactful retained primitive reflexes are to the developmental blueprint of a child's brain. In addition, Dr. Melillo and Dr. Scire highlight how to use the Melillo Method home assessment to determine if your child has a developmental brain imbalance.
16 Aug 2024
The Attentional Divide
How does telling some they have ADHD help them understand what is going on inside their brain? Is it possible the symptoms and gifts that they possess are really a difference in the developmental maturation of their 2 hemispheres? Could immaturity in either hemisphere be responsible for attentional issues, hyperactivity, and impulsivity? Dr. Melillo and his colleague Dr. Scire will explore how each hemisphere has a role in the various forms of attention while also discussing how the symptoms of hyperactivity, impulsivity, tics that are present in ADHD are because pathways from the frontal lobes are developmental immature.
5 Aug 2024
A global message of Hope: The Disconnected Kids book
Finally, the new edition of the Disconnected Kids is available. 15 years after its initial release the new edition expands on the extensive research and clinical work that Dr. Melillo conducted while pursuing his PhD. Dr. Melillo catches up with Dr. Scire to discuss the contents of the new book but also takes us back on how the original book came about and the impact that the book has had world wide over these past 15 years.
22 Jul 2024
Synchronicity: How does our brain use the concept of timing to coordinate its neural networks?
How often do we use the expression “timing is everything”? In the human brain it literally is! Dr. Melillo, co-host Dr. Scire and CEO of Interactive Metronome Matt Wukasch discuss how a computerized metronome device which arouse from a musician’s need to help other musicians keep time can now help clinicians and therapists reestablish abnormal timing within the brain networks that oversee executive functions, attention, speech, sensory and motor functions and much more.
8 Jul 2024
Getting inside the mind of Dr. Melillo. Past, Present and Future of the Melillo Method.
Have you ever wondered about how did Dr. Robert Melillo developed the Melillo Method?
During this episode, Dr. Melillo and his co-host Dr. Scire explore the origins of his theories on
brain development, functional disconnection syndrome and the role right and left hemispheres
functional differences play in childhood developmental disorders such as Autism, ADHD,
Dyslexia, Learning Disabilities, OCD, Tics/Tourettes, and Anxiety. Throughout the episode Dr.
Melillo and Dr. Scire discuss research papers that Dr. Melillo has published over the past 15
years that explore groundbreaking concepts of interoception(sense of self), embodiment,
attachment and brain-immune connections.
3 Apr 2024
The Epidemic of Anxiety, what is happening in the Brain and how to eliminate it
In this episode Dr. Robert Melillo and Dr. Peter Scire discuss different types of anxiety especially “right brain anxiety”. In this they discuss differences in the emotional regulation of the right and left hemispheres of the brain and how imbalances between them can produce various symptoms. In this episode, they specifically discuss right hemisphere anxiety which is caused by overactivity of the right hemisphere and underactivity of the left hemisphere. The right hemisphere emotions are fear (sense of danger), Sadness, Embarrassment, shame, guilt, disgust and rejection sensitivity. Overactivity of these emotions can lead to severe social anxiety, low self-esteem, feelings of being judged by others and one self. There is also decreased emotions of happiness, joy and pride which are left brain emotions, this can also cause depression along with anxiety and in extreme cases this is the foundation of bipolar disorder. They also discuss ways to help restore proper brain function and reduce or eliminate these symptoms.
Reach and audience
Public platform figures. Ratings count people who left a rating, not total listeners.
YouTube views
549,100
Score snapshot 15 Sept 2025
Apple Podcasts (US)
4.8 / 5
17 ratings
Spotify
5.0 / 5
25 ratings
Podcast Authority Score: 37 / 100
A composite of feed quality, social presence, YouTube performance and engagement. Read the methodology.
Quality
20
Social presence
0
YouTube
86
Engagement
51
Host of Melillo Method Podcast, Everything Brain?
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