Each week, MIB Agents talks with the leaders and innovators in osteosarcoma surgery, research, treatment and advocacy. Questions are taken during the webinar and are included in each podcast. More information is available at www.mibagents.org
A Phase 1 Trial evaluating Folate Receptor Alpha CAR T cells for Advanced Osteosarcoma
Dr. Michelle Choe will introduce a phase 1 clinical trial currently open at Fred Hutch Cancer Center for folate receptor alpha (FOLR1)-CAR T cells for pediatric and adult patients with relapsed/refractory osteosarcoma after front-line therapy. This clinical trial is currently actively accruing and treating patients. The primary objective of the study is to evaluate the safety and tolerability of FOLR1-CAR T cells and to identify the recommended phase 2 dose. The secondary objective includes evaluating the antitumor activity of FOLR1-CAR T cells in patients.
29 Sept 2026
MISTOSUS: A phase II clinical trial of IscadorP (Mistletoe extract) as immunotherapy to improve event-free survival in patients with relapsed resectable osteosarcoma
There is an urgent need for safe and effective therapies to improve outcomes for patients with relapsed osteosarcoma. Viscum album extract (Iscador P, Iscador AG, Arlesheim, Switzerland) is a mistletoe extract manufactured from the leaves, stems and berries of Viscum album L., grown on pine trees (P = Pini). It has shown efficacy and safety in lab experiments and small clinical trials for patients with relapsed osteosarcoma. Data from a small pilot study in Italy paved the way for developing a larger clinical trial in the United States to test the use of Viscum album extract for children, teenagers, and young adults with osteosarcoma that has come back and can be removed with surgery. Another goal of this study is to learn more about what impact Viscum Album extract may have on patients' quality of life, tumor biology and immune system during treatment.
17 Sept 2026
osTEAo: Let's Talk Childhood Cancer
This month on osTEAo, Sammy, Inaaya, Mackenzie, and Keely discuss Childhood Cancer Awareness Month, how childhood cancer is portrayed and understood, and what those portrayals can miss about the realities of a cancer diagnosis. They share personal experiences and perspectives on awareness, treatment, advocacy, and the different ways patients, siblings, and families experience childhood cancer. They also reflect on the importance of supporting families who are grieving while continuing to raise awareness and create a better understanding of childhood cancer. Tune in for an honest conversation about childhood cancer awareness from the perspective of survivors and siblings.
Who has been a guest on MIB Agents OsteoBites
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Yingqi Hua
Sloane
Matthew
Damon Reed
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Apple Podcasts (US)
5.0 / 5
5 ratings
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