Jeremy Murphree discusses the latest research of Morgellons disease.
Morgellons Discussion
Claim This Podcastby Jeremy Murphree
4.8(5 reviews)
58 episodes
Updated Weekly
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42
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Podcast Overview
Jeremy Murphree discusses the latest research of Morgellons disease.
Language
🇺🇲
Publishing Since
9/18/2020
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42
Podcast Authority
BetaFairBased on show quality, social media presence, reviews, charts, and more
Quality72
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Engagement32
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Recent Episodes
April 24, 2026
New Morgellons Research? Say Whaaaaaaat! with Crystal Clear 🤯
<p>In this powerful crossover episode of Morgellons Discussion, host Jeremy Murphree sits down with Crystal Clear from the More Morgellons Podcast (moremorgellons.com) to break down the brand-new preprint study that’s sending shockwaves through the Morgellons community: “Metagenomics reveals a phylogenetically informed microbial signature associated with Morgellons disease” by Lambert and Kindschuh (bioRxiv, April 15, 2026). </p><p><br></p><p>For years, patients have been told Morgellons is “all in their head.” This study says otherwise—loudly and with data. Using deep metagenomic sequencing on skin lesions from a family cohort, the researchers uncovered a distinct “shadow biome”: massive amounts of previously unclassified microbial DNA (61.4% unclassified non-human sequences in lesions vs. just 34% in healthy skin), a complete ecological takeover by Pseudomonadota and Bacteroidota, and a phylogenetically informed microbial signature tied directly to symptom severity. Even the infamous fibers? Confirmed as human keratin and collagen—not lint, not delusion. </p><p><br></p><p>Jeremy and Crystal Clear unpack the methods, the groundbreaking findings, what the “Symptomatic Subtree” means for patients with fatigue and cognitive issues, and why this research finally gives the scientific community hard evidence that Morgellons is a real, biologically driven condition—not “delusional parasitosis.” </p><p><br></p><p>If you’ve been fighting for answers, this episode is validation, hope, and the next chapter in the fight to be taken seriously. </p><p><br></p><p><strong> Listen now and share with anyone who still thinks Morgellons is “just mental.”</strong></p><p><br></p><p> Study breakdown: <a href="https://www.morgellons.io/new-research/new-metagenomic-evidence/ " target="_blank" rel="ugc noopener noreferrer">https://www.morgellons.io/new-research/new-metagenomic-evidence/ </a></p><p><strong>Correction from last night’s episode with Crystal Clear!</strong> 🎙️🧬</p><p>I wanted to clarify a detail regarding the paper I discussed: "Reframing delusional infestation: perspectives on unresolved puzzles." During the show, I mentioned it was published in the journal <strong>General Psychiatry</strong> (which previously held a high Impact Factor of <strong>11.9, </strong>presently at<strong> 7</strong>). </p><p>It was actually published in <strong>Psychology Research and Behavior Management</strong>.</p><p>The "11.9" was on my mind because the authors (Lai, Xu, and Hu) are world-class researchers whose work often appears in General Psychiatry. I associated their high-caliber output with that specific journal’s impact factor.</p><p>While the publication venue is different, the paper’s significance remains: it’s a major call for the medical community to stop dismissing patients and start looking at the "unresolved puzzles" of these symptoms through a more comprehensive, clinical lens.</p><p>Accuracy is key when we're talking about real research. Thanks for tuning in! 🎧</p><p><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC6171510/">Reframing delusional infestation: perspectives on unresolved puzzles - PMC</a>#Morgellons #MedicalResearch #MorgellonsDisease #GeneralPsychiatry #ClinicalUpdate #FactCheck #CrystalClear</p><p><br></p><p>You can reach Crystal Clear at her website <a href="https://www.moremorgellons.com/" target="_blank" rel="ugc noopener noreferrer">More Morgellons</a>Listen to Crystal Clear's podcast <a href="https://anchor.fm/more-morgellons" target="_blank" rel="ugc noopener noreferrer">More Morgellons</a></p>
April 3, 2026
Silenced by Similarity: How the Syphilis Comparison Shut Down Morgellons Research
<p>In February 2020, a groundbreaking peer-reviewed paper titled “Classification and Staging of Morgellons Disease: Lessons from Syphilis” dropped a bombshell. Researchers showed that Morgellons lesions mirror secondary syphilis in their wildly variable appearance, spirochetal burden (Borrelia in skin cells), and histopathological patterns. They even proposed a new staging system modeled directly on syphilis.</p><p>Then… the information flow about Morgellons virtually stopped.</p><p>No major new studies. Minimal mainstream coverage. Dermatology guidelines still call it delusional infestation. Even within the patient community, the full spirochetal picture — especially the syphilis parallels and visible fibers/sores — gets sidelined or ignored.</p><p>In this episode, I break down the 2020 paper’s key findings, the suspicious silence that followed, and why almost nobody outside a small research circle wants to engage with this science. I also call out the gaps: the Charles E. Holman Foundation runs conferences and the Morgellons Lived Experience Project, but isn’t pushing the syphilis staging research hard enough through aggressive outreach. </p><p>Meanwhile, some Lyme doctors like Daniel Cameron acknowledge crawling and biting sensations as neurologic Lyme symptoms, yet downplay the dermopathy, fibers, and full Morgellons picture.</p><p>If Morgellons is another spirochetal infection like syphilis or chronic Lyme, patients deserve real testing, treatment discussions, and answers — not silence.</p><p>Listen as we examine how the moment the science got too real, the conversation went quiet. Read the 2020 paper yourself (link below), demand better outreach from patient organizations, and help force this discussion back into the light.</p><p>2020 Paper: <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC7012249/" target="_blank" rel="noopener noreferer">https://pmc.ncbi.nlm.nih.gov/articles/PMC7012249/ </a></p><p>Charles E. Holman Foundation: thecehf.org (support them… but push them for more outreach!) </p><p>Daniel Cameron article on crawling sensations: danielcameronmd.com (example of narrowed view) </p><p>Sources: Middelveen et al. 2020, CDC 2012 contrast, recent patient registry updates</p>
January 24, 2026
Morgellons Disease: Bacterial Truth vs. Psychiatric Myth
<p><strong>Morgellons is not a mystery; it is microbiology.</strong> In this 15-minute clinical briefing, host Jeremy Murphree strips away the stigma of "unexplained dermopathy" and replaces it with a concrete bacterial framework. For years, patients have been trapped in the "Delusional Parasitosis" (DP) label—a diagnostic dead end that halts medical investigation. Today, we turn the tide.</p><p><strong>In this episode, we cover:</strong></p><ul><li><p><strong>The Diagnostic Barrier:</strong> Why the DP label is used to gaslight patients and how to bypass the "negative test trap."</p></li><li><p><strong>The Spirochetal Link:</strong> Exploring the connection between Borrelia (Lyme Disease), Syphilis, and the cutaneous manifestations of infection.</p></li><li><p><strong>Biofilm Science:</strong> How mixed biofilms and proteins like β-amyloid protect pathogens from the immune system.</p></li><li><p><strong>The Middelveen Criteria:</strong> Breaking down the Stages A–C of infection and the truth about human biofilaments (keratin/collagen) vs. textile myths.</p></li><li><p><strong>Your Action Plan:</strong> How to find ILADS-trained doctors, demand "Direct Detection" (PCR/FISH) testing, and access financial aid.</p></li></ul><p><strong>Stop fighting for belief and start fighting with biochemistry.</strong></p><ul><li><p><strong>Middelveen, M. J., et al. (2015).</strong> Exploring the association between Morgellons disease and Lyme disease: identification of Borrelia burgdorferi in Morgellons disease patients. BMC Dermatology. <a href="https://doi.org/10.1186/s12895-015-0023-0" target="_blank" rel="noopener">Read the full study here</a>.</p><p>Key takeaway: Confirmed the presence of spirochetes in 24 out of 25 MD patients.</p></li><li><p><strong>Middelveen, M. J., et al. (2020).</strong> Classification and Staging of Morgellons Disease: Lessons from Syphilis. Clinical, Cosmetic and Investigational Dermatology. <a href="https://doi.org/10.2147/CCID.S239840" target="_blank" rel="noopener">Read the full study here</a>.</p><p>Key takeaway: Establishes the Classes I-IV and Stages A-C framework used in the episode.</p></li><li><p><strong>Middelveen, M. J., & Stricker, R. B. (2016).</strong> Morgellons disease: a filamentous borrelial dermatitis. International Journal of General Medicine. <a href="https://doi.org/10.2147/IJGM.S116608" target="_blank" rel="noopener">Read the full study here</a>.</p><p>Key takeaway: Provides the histological proof that fibers are human biofilaments (keratin/collagen).</p></li></ul><ul><li><p><strong>Ekbom, K. A. (1938).</strong> Der prasenile Dermatozoenwahn. (The original study on "delusions" where subjects actually had syphilis).</p></li><li><p><strong>Vié, J. (1935).</strong> Les idées de possession et d'infestation parasitaires. (Early documentation of spirochetal links to parasitic delusions).</p></li><li><p><a href="https://morgellons.io/learn/">The New Morgellons Movement - Free Morgellons Course</a></p></li></ul><ul><li><p><strong>The Charles E. Holman Morgellons Disease Foundation (CEHMDF):</strong> The leading source for MD research, patient education, and financial aid information. <a href="https://thecehf.org" target="_blank" rel="noopener">Visit thecehf.org</a>.</p></li><li><p><strong>ILADS (International Lyme and Associated Diseases Society):</strong> For finding clinicians who specialize in complex tick-borne infections and intracellular-targeting protocols. <a href="https://www.ilads.org" target="_blank" rel="noopener">Visit ilads.org</a>.</p></li><li><p><strong>IU Indianapolis ScholarWorks:</strong> For accessing the latest posters and data on the diagnostic overlaps between DP and MD. <a href="https://scholarworks.indianapolis.iu.edu/" target="_blank" rel="noopener">Search the Repository</a>.</p></li></ul><ul><li><p><strong>Tick-Borne Disease Working Group (TBDWG):</strong> 2020 Report to Congress. This report acknowledges the gaps in diagnosis and the need for better validation of Lyme-related conditions. <a href="https://www.google.com/search?q=https://www.hhs.gov/ash/advisory-committees/tickbornedisease/reports/2020-report-to-congress/index.html" target="_blank" rel="noopener">Download the 2020 Report</a>.</p></li></ul>
58 total episodes available
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