Cancer is a fascinating but rapidly evolving discipline - it's a full-time job just keeping up to date. In this podcast, Dr Michael Fernando and Dr Joshua Hurwitz explore the latest trials, research, and practice-changing updates, as well as regular interviews with renowned oncology specialists. Ideal for those starting their training journey, established specialists and anyone interested in medical science, oncological practice, or terrible jokes. Preferably all three.<hr><p style='color:grey; font-size:0.75em;'> Hosted on Acast. See <a style='color:grey;' target='_blank' rel='noopener noreferrer' href='https://acast.com/privacy'>acast.com/privacy</a> for more information.</p>

Oncology for the Inquisitive Mind
Claim This Podcastby Michael Fernando and Josh Hurwitz
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Podcast Overview
Cancer is a fascinating but rapidly evolving discipline - it's a full-time job just keeping up to date. In this podcast, Dr Michael Fernando and Dr Joshua Hurwitz explore the latest trials, research, and practice-changing updates, as well as regular interviews with renowned oncology specialists. Ideal for those starting their training journey, established specialists and anyone interested in medical science, oncological practice, or terrible jokes. Preferably all three.<hr><p style='color:grey; font-size:0.75em;'> Hosted on Acast. See <a style='color:grey;' target='_blank' rel='noopener noreferrer' href='https://acast.com/privacy'>acast.com/privacy</a> for more information.</p>
Language
🇺🇲
Publishing Since
7/31/2022
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Recent Episodes

July 12, 2026
208. ASCO 2026 - The Plenary Episode - Part 3
<p>This episode is the ASCO 2026 Plenary Episode. This week, all of the pivotal, game-changing, life-changing trials are discussed here. Some describe the plenary session as practice-changing, and we will always agree that better treatments with significant improvements in life expectancy and quality of life need their time in the spotlight.</p><br><p>Today, five trials are discussed, including SARC041, a liposarcoma study utilising the CDK 4/6 inhibigtor abemacicilib. Our second study is HARMONI-6, investigating whether ivonescimab plus chemotherapy is effective in patients with advanced squamous non-small cell lung cancer. Our third, almost like something written for an opera (LIBRETTO0-432), a lung cancer trial looking at selpercatinib in those with RET fusion early-stage NSCLCa. PROTEUS emerges as our fourth trial, rising from the depths of the ocean to evaluate apalutamide in the perioperative prostate cancer space.</p><br><p>Finally, and most importantly in our opinion, is RASolute302, the pancreatic cancer trial, showing that even the most difficult mutation is now treatable. An incredible story of an exceptionally difficult cancer to treat, Daraxonrasib is the star of this year's ASCO.</p><br><p><strong>Studies Discussed in this Episode</strong></p><p><strong>SARC041</strong></p><p><strong>HARMONI-6</strong></p><p><strong>LIBRETTO0-432</strong></p><p><strong>PROTEUS</strong></p><p><strong>RASolute302</strong></p><br><p>For more episodes, resources and blog posts, visit <a href="https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/www.inquisitiveonc.com" rel="noopener noreferrer" target="_blank">www.inquisitiveonc.com</a></p><p>Please find us on Twitter <a href="https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/@InquisitiveOnc!" rel="noopener noreferrer" target="_blank">@InquisitiveOnc!</a></p><p>If you want us to look at a specific trial or subject, email us at <a href="mailto:inquisitiveonc@gmail.com" rel="noopener noreferrer" target="_blank">inquisitiveonc@gmail.com</a></p><br><p>Art courtesy of Taryn Silver</p><p>Music courtesy of AlisiaBeats: https://pixabay.com/users/alisiabeats-39461785/</p><br><p>Disclaimer: This podcast is for educational purposes only. If you are unwell, seek medical advice.</p><br><p>Oncology for the Inquisitive Mind is recorded with the support of education grants from our foundation partners Pfizer and Merck Pharmaceuticals. Our partners have access to the episode at the same time you do and have no editorial control over the content.</p><hr><p style='color:grey; font-size:0.75em;'> Hosted on Acast. See <a style='color:grey;' target='_blank' rel='noopener noreferrer' href='https://acast.com/privacy'>acast.com/privacy</a> for more information.</p>

July 5, 2026
207. ASCO 2026 - Agents of the Future - Part 2
<p>This week, Josh and Michael's ASCO 2026 coverage looks at "Agents of the Future", trials of intrigue, promise and potential beyond its status. This episode also sheds light on more orphan status cancers like head and neck cancer, basket cohort studies, resistant EGFR lung cancer, metastatic colorectal cancer and hepatocellular carcinoma.</p><br><p>One more episode left of this arc - The Plenary! Stay tuned.</p><br><p><strong>Studies Discussed in this Episode</strong></p><p>OrigAMI-4</p><p>WU-KONG28</p><p>A Phase 1/2 Study of JK06, a 5T4-Targeted Antibody Drug Conjugate (ADC), In Patients with Unresectable Locally Advanced or Metastatic Cancer</p><p>ESANOA</p><p>ROSETTA Lung-02</p><p>Ivonescimab + FOLFOX</p><p>HERIZON-CRC01</p><p>CIRCULATE</p><p>EMERALD-3</p><p>BLUESTAR</p><p>GLP-1 agonist in breast cancer (Palleschi et al)</p><br><p>For more episodes, resources and blog posts, visit <a href="https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/www.inquisitiveonc.com" rel="noopener noreferrer" target="_blank">www.inquisitiveonc.com</a></p><p>Please find us on Twitter <a href="https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/@InquisitiveOnc!" rel="noopener noreferrer" target="_blank">@InquisitiveOnc!</a></p><p>If you want us to look at a specific trial or subject, email us at <a href="mailto:inquisitiveonc@gmail.com" rel="noopener noreferrer" target="_blank">inquisitiveonc@gmail.com</a></p><br><p>Art courtesy of Taryn Silver</p><p>Music courtesy of AlisiaBeats: https://pixabay.com/users/alisiabeats-39461785/</p><br><p>Disclaimer: This podcast is for educational purposes only. If you are unwell, seek medical advice.</p><br><p>Oncology for the Inquisitive Mind is recorded with the support of education grants from our foundation partners Pfizer and Merck Pharmaceuticals. Our partners have access to the episode at the same time you do and have no editorial control over the content.</p><hr><p style='color:grey; font-size:0.75em;'> Hosted on Acast. See <a style='color:grey;' target='_blank' rel='noopener noreferrer' href='https://acast.com/privacy'>acast.com/privacy</a> for more information.</p>

June 28, 2026
206. ASCO 2026 - Part 1
<p>ASCO 2026 is done, and Michael and Josh have created a marathon episode for you all. This week we cover "Agents of the Present", where we summarise all the important trials with updates, overall survival and progression-free survival data that could influence your practice.</p><br><p>They cover immunotherapy, lifestyle interventions, pan-PI3K inhibitors, rare cancers (such as uveal melanoma), and antibody drug conjugates, to name a few. All the cancer types are covered, including genitourinary, gynaecological cancers, breast, colorectal, lung and lifestyle interventions!</p><br><p>Two more episodes to come!</p><br><p><strong>Studies Discussed in this Episode</strong></p><p>EV-302 Extended Follow-Up</p><p>ROSELLA (Ovarian Cancer)</p><p>RAMPART (Adjuvant RCC)</p><p>VIKTORIA-1 (HR +ve Breast Cancer)</p><p>OptimUM</p><p>OPTIMA (Breast Cancer)</p><p>Anbenitimab and Chemotherapy (HER2 +ve Breast Cancer)</p><p>TALAPRO-3 (Prostate Cancer)</p><p>GLP-1 in HR +ve Breast Cancer</p><p>Lifestyle Interventions in HR +ve Breast Cancer</p><br><p>For more episodes, resources and blog posts, visit <a href="https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/www.inquisitiveonc.com" rel="noopener noreferrer" target="_blank">www.inquisitiveonc.com</a></p><p>Please find us on Twitter <a href="https://open.acast.com/networks/62d20dbcffef490011c8df4d/shows/62d20dbcffef490011c8df4b/episodes/@InquisitiveOnc!" rel="noopener noreferrer" target="_blank">@InquisitiveOnc!</a></p><p>If you want us to look at a specific trial or subject, email us at <a href="mailto:inquisitiveonc@gmail.com" rel="noopener noreferrer" target="_blank">inquisitiveonc@gmail.com</a></p><br><p>Art courtesy of Taryn Silver</p><p>Music courtesy of AlisiaBeats: https://pixabay.com/users/alisiabeats-39461785/</p><br><p>Disclaimer: This podcast is for educational purposes only. If you are unwell, seek medical advice.</p><br><p>Oncology for the Inquisitive Mind is recorded with the support of education grants from our foundation partners Pfizer and Merck Pharmaceuticals. Our partners have access to the episode at the same time you do and have no editorial control over the content.</p><hr><p style='color:grey; font-size:0.75em;'> Hosted on Acast. See <a style='color:grey;' target='_blank' rel='noopener noreferrer' href='https://acast.com/privacy'>acast.com/privacy</a> for more information.</p>
226 total episodes available
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