Conversations about medicine, health, aesthetics, wellness, internet trends, and the realities of modern healthcare from the perspective of a board-certified internal medicine physician. Some episodes break down medical misinformation. Some unpack what patients are actually struggling with. Some are just honest conversations out loud.
What Primary Care Doctors Wish Patients Understood
In this episode of Out Loud, Dr. Makkani is joined by Dr. Javier “Kenji” Martinez, a family medicine physician in Miami, for an honest conversation about primary care, physician voices on social media, and the realities of taking care of patients in a healthcare system that often makes good care harder to deliver.
They discuss what patients often misunderstand about primary care, the difference between MDs and DOs, why medicine is not one-size-fits-all, and how social media can both educate and mislead patients.
They also talk about supplements, annual physicals, insurance rules, social determinants of health, and the emotional weight physicians carry when patients cannot access or afford the care they need.
This conversation is about medicine beyond the diagnosis — the patient, the system, the barriers, and the people trying to help from inside it.
18 Jun 2026
Treating Obesity Without Shame: Beyond the GLP-1 Hype with Dr. Aryanna Amini
In this episode of Out Loud, Dr. Makkani is joined by Dr. Aryanna Amini, a board-certified family medicine physician with additional certification in sports medicine and obesity medicine.
They talk about what obesity medicine actually looks like beyond the online noise around GLP-1 medications. The conversation covers obesity as a chronic medical condition, the stigma patients carry, realistic expectations with GLP-1s, muscle preservation, strength training, compounded medications, access, nutrition, and why weight alone should not be the only measure of health.
They also discuss how social media has shaped the way patients think about weight loss, why many patients feel shame even asking for help, and what more thoughtful, weight-neutral obesity care can look like in real clinical practice.
This episode is a grounded physician-to-physician conversation about obesity, GLP-1s, metabolic health, and treating patients without judgment.
Dr. Amini's social media: @draryannaamini
Dr. Makkani's social media: @drmakkani
11 Jun 2026
GLP-1s, Compounding, and the Problem With Casual Prescribing
GLP-1 medications have changed the way we treat obesity, diabetes, and metabolic disease.
In this episode, I talk about compounded GLP-1s, online prescribing, and why the process around these medications matters — including dosing, follow-up, patient selection, and informed consent.
This is not a conversation about fear. It is a conversation about treating these medications with the medical oversight they deserve.
4 Jun 2026
When Women’s Health Became a Social Media Industry
Women’s health is finally being talked about more openly and that matters.
But somewhere along the way, hormones, cortisol, inflammation, gut health, perimenopause, PCOS, supplements, and “wellness” became one of the biggest industries on the internet.
In this episode of Out Loud, Dr. Makkani talks about why so many women have felt dismissed for years, why online health content can feel validating, and how fear-based wellness marketing can turn women’s bodies into another optimization project.
Women deserve thoughtful, evidence-based conversations about their health without being dismissed by medicine or manipulated by marketing.
Episode 2: When Women’s Health Became a Social Media Industry
28 May 2026
Why Healthcare Feels So Confusing Right Now
Out Loud with Dr. Makkani is a podcast about medicine, wellness, aesthetics, misinformation, and the realities of modern healthcare from the perspective of a board-certified internal medicine physician.
Some episodes break down confusing health trends and viral medical claims. Some explore the systems, burnout, and frustrations shaping the way patients experience healthcare today. Others are honest conversations with physicians, creators, researchers, and people working inside health and wellness.
This is where evidence-based medicine meets real life.
Thoughtful. Grounded. Honest. Human.
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