Welcome to the Practical Medicine Podcast for the wards, for the boards, and for all of the nerds! Whether you're a student, resident, or a seasoned pro, we have something for everyone to help you grow. We tackle complex topics and make them simple, all this to make your mind nimble. Sit back and relax and absorb what you can, here you'll find all you need to start making the perfect clinical plan.
Cervical Cancer1. Etiology and Risk Factors: - Human Papillomavirus (HPV): Causative agent in 99.7% of cases - Risk factors: a) Early onset of sexual activity b) Multiple sexual partners c) Immunosuppression (including HIV) d) Low socioeconomic status e) Smoking f) Oral contraceptive use2. Histology: - Squamous cell carcinoma: 69% - ...
6 Aug 2024
ABIM Oncology - Ovarian Cancer
Ovarian Cancer1. Epidemiology and Risk Factors: - Major risks: Genetic mutations (BRCA1, BRCA2, MMR genes), age, infertility, nulliparity, endometriosis, PCOS, smoking - 10-15% of patients carry mutations - All epithelial ovarian cancer patients should get BRCA1/2 testing - MMR testing for Lynch syndrome history - Lifetime risk: BRCA1 carriers 45%, others 3-12%2. Risk-Reduction: - BRCA1/2 or MMR carriers: Prophylactic bil...
5 Aug 2024
ABIM Oncology - Breast Cancer
Epidemiology & Risk Factors:- Most common cancer in US women (excluding skin cancers)- Lifetime risk: 12% (1 in 8 women)- Incidence increases with age; median age at diagnosis: 61 years- Highest incidence in non-Hispanic White and Black women- Risk factors: BRCA1/2 mutations (45-75% lifetime risk), chest irradiation age 10-30 (30-50% risk), atypical hyperplasia/LCIS (35% risk at 30 years)Screening & Prevention:- Average risk: Annual mammogram starting age 45-50- High risk: Annual mamm...
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