Precision Medicine Podcast

About Precision Medicine Podcast

Welcome to the Precision Medicine Podcast by Trapelo. Created and hosted by patient advocate Karan Cushman, this is the podcast where leading voices in cancer explore how to bring precision medicine to patients everywhere.

Publisher

Trapelo

Category

health & fitness · news · science

Language

en

Explicit

No

First episode

28 Nov 2018

Latest episode

2 Dec 2025

Latest episodes

69 episodes in the feed.

1. 

   2 Dec 2025

   Liquid Biopsy for Precision Medicine: What’s Actionable Now and What’s Next

   Advances in molecular diagnostics are reshaping how cancer is detected, monitored, and treated, and liquid biopsy is becoming central to that progress. This simple blood draw can reveal key tumor biology at diagnosis and over time, providing timely insight and guiding more precise decisions throughout a patient’s journey. Clinicians now face an important challenge: knowing what is actionable today and what is coming next so more patients can benefit from the promise of these advances.As we kick off Season 7, host and patient advocate Karan Cushman expands this season’s focus on Bringing Precision Medicine to Everyone with a deeper look inside the science of liquid biopsy. The conversation features two leaders shaping the field: Dr. Christian Rolfo, Division Director of Medical Oncology at The James Comprehensive Cancer Center at Ohio State University, and Dr. Roberto Borea, Medical Oncologist and emerging investigator from the Rolfo Lab.Together, they break down the scientific momentum driving liquid biopsy forward, including tumor fraction, MRD-guided treatment strategies, resistance monitoring, fragmentomics, and the expanding frontier of early detection. They also discuss the barriers that continue to slow broader adoption, such as assay variability, limited standardization, reimbursement gaps, and operational challenges in community settings.In this episode, we cover:• How tumor fraction is emerging as a meaningful real-time biomarker• Where MRD-driven escalation and de-escalation strategies are heading• The current promise and limitations of early detection and MCED testing• What is required to standardize liquid biopsy across reporting, workflows, and clinical trialsEpisode 70 offers a clear look at the advances researchers are helping drive right now and what these developments could mean for clinicians, laboratories, and patients in the near future.This conversation builds on episode 69 with Dr. Kashyap Patel, who introduced the foundations of liquid biopsy and its role in accelerating treatment decisions. Combined, these two episodes offer clinicians and patients an overview of where the science and real-world applications stand now and where the field is headed next.

2. 

   23 Sept 2025

   Liquid Biopsy Part 1: Breaking Speed and Access Barriers in Precision Oncology

   Liquid biopsy is breaking speed and access barriers in precision oncology. In this episode of the Precision Medicine Podcast, part of our series Bringing Precision Medicine to Everyone and the first in a two-part focus, founder and host Karan Cushman speaks with Dr. Kashyap Patel, CEO of Carolina Blood and Cancer Care Associates, author, and national leader in value-based oncology.Together, they explore how liquid biopsy is changing the diagnostic and treatment landscape. This blood-based test can deliver results in days, be repeated as needed, and reduce the need for invasive procedures. Tissue biopsy remains important, but when the samples are too small or unsuitable for testing, liquid biopsy provides a valuable alternative in guiding treatment decisions and monitoring disease.For patients with aggressive “turbo cancers” such as diffuse large B-cell lymphoma or small cell lung cancer, the time saved can be lifesaving. Karan shares her own experience with DLBCL, while Dr. Patel highlights real-world cases where liquid biopsy revealed actionable mutations, informed therapy, or enabled minimal residual disease (MRD) monitoring.Finally, Dr. Patel underscores the need for standardization and payer alignment to move liquid biopsy from innovation to everyday practice. This candid discussion frames liquid biopsy not as a futuristic idea, but as a clinically powerful and scalable tool that is closing gaps in precision oncology today.

3. 

   9 Jul 2025

   Bringing Precision Medicine—and Compassion—to Every Cancer Journey with Dr. Arif Kamal

   American Cancer Society Chief Patient Officer Dr. Arif Kamal discusses with Karan Cushman bringing precision medicine and compassion to cancer care, emphasizing equity and addressing barriers like geography and affordability in this interview.

Who has been a guest on Precision Medicine Podcast

Names identified in recent episode analyses. Showing up to five guests.

• Dr Arif Kamal
• Ellen Matloff
• Dr Angella Charnot-Katsikas
• Dr Kashyap Patel
• Dr Douglas Flora

Reach and audience

Public platform figures. Ratings count people who left a rating, not total listeners.

YouTube views

327

Score snapshot 15 Sept 2025

Apple Podcasts (US)

4.8 / 5

33 ratings

Spotify

5.0 / 5

6 ratings

Podcast Authority Score: 62 / 100

A composite of feed quality, social presence, YouTube performance and engagement. Read the methodology.

Quality

77

Social presence

0

YouTube

66

Engagement

51

Contact Precision Medicine Podcast

Guest appearances

Books guests

Based on episode analysis; this does not confirm that the show is currently accepting guests.