The BioInsights Podcast

About The BioInsights Podcast

The BioInsights Podcast: discussing the challenges of translating novel biologics from bench to clinic to market.

Publisher

BioInsights

Category

business · science · science

Language

en

Explicit

No

First episode

10 May 2022

Latest episode

6 Oct 2026

Latest episodes

3 of 61 episodes have a transcript.

1. 

   6 Oct 2026

   Making the Move to AAV producer cell lines: comparability, bridging studies and regulatory considerations

   Lauren Coyle interviews Lonza's Laura Sands, Ramesh Koukuntla, Wenling Dong, and Vijetha Bhat on navigating regulatory hurdles and comparability studies for AAV producer cell line transitions.

2. 

   24 Jun 2026

   From one target to many: how high‑plex ddPCR is changing CGT from development to analytics

   Lauren Coyle, Editor, BioInsights, speaks with Christian Overgaard, Senior Field Application Scientist, Bio‑Rad Laboratories, about the technical and practical evolution of droplet digital PCR (ddPCR) and high‑plex multiplexing, covering assay design challenges, vector integration analysis, biodistribution studies, and the emerging role of digital PCR in cell and gene therapy characterization and clinical development.

3. 

   17 Jun 2026

   Beyond one and done: engineering durable, redosable cell‑based gene therapies

   The one‑and‑done model has defined gene therapy for a generation. Chris Hopkins thinks it is time to move on. At ASGCT 2026, Abi Pinchbeck spoke with the Co‑founder and CEO of Glafabra Therapeutics on redoseable cell‑based gene therapy, a platform spanning Fabry, Pompe, and Gaucher diseases, and what durable, if not permanent, treatment could mean for patients. A podcast version of this discussion is also available.

Inside a recent episode

Crossing the ADC inflection points: what separates clinical success from failure

Published 23 Feb 2026 · Transcript excerpt

[…] I try to give you, I mean, an answer which makes sense, at least this is how I approach, I would advise, or I advise the development teams on thinking, you know, essentially you have, you have three legs, you know. One is, do not assume you understand completely your MOA, it's not because of the target that, you know, your MOA is actually fully understood by MOA, I mean, the mechanism of action. You know, the heavy lifting work which has been done by Gustav Rusy on the so -called Daisy trial and then the Harris program, which really, you know, decompreated completely the mechanism by which the drug on ADC binds itself to which receptor, how it graphics, how it is released and how the special temporal distribution of the cells, which picked up the drug, released it and then the bisoner effect, all of this, how it affects the actual effect in the human tubers, you know, is critically important. […]

Who has been a guest on The BioInsights Podcast

Names identified in recent episode analyses. Showing up to five guests.

• Laura Sands
• Ramesh Koukuntla
• Wenling Dong
• Vijetha Bhat
• Jokūbas Leikauskas

Reach and audience

Public platform figures. Ratings count people who left a rating, not total listeners.

Apple Podcasts (US)

5.0 / 5

4 ratings

Spotify

5.0 / 5

5 ratings

Podcast Authority Score: 28 / 100

A composite of feed quality, social presence, YouTube performance and engagement. Read the methodology.

Quality

28

Social presence

0

YouTube

0

Engagement

68

Contact The BioInsights Podcast

Guest appearances

Does not typically book guests

Based on episode analysis; this does not confirm that the show is currently accepting guests.

Questions about The BioInsights Podcast