In this special episode of Two Brothers, One Prostate (https://www.facebook.com/profile.php?id=61589440547973), Kevin and John talk with Ed St. John about his prostate cancer journey. Together, they discuss the emotional challenges, medical insights, and upcoming fundraising events that aim to raise awareness and support for prostate cancer patients. Ed also shares his experience with the PC Tribe (https://pctribe.org/) support group and highlights the importance of community support and advocacy for men facing similar challenges.
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13 Aug 2026
Two Bros, One Pro
In this special episode of Two Brothers, One Prostate (https://www.facebook.com/profile.php?id=61589440547973), Kevin and John sit down with world-renowned medical oncologist Dr. Nabil Adra (https://www.linkedin.com/in/nabil-adra-454bb023/) from the IU Simon Comprehensive Cancer Center (https://cancer.iu.edu/) for an engaging and insightful conversation on men’s health and the evolving landscape of prostate cancer care. Dr. Adra breaks down the importance of early detection, understanding PSA scores and genetic factors, navigating aggressive diagnoses, and the vital role clinical trials play in advancing targeted therapies and potential cures. The brothers share their personal journeys, from stage four metastatic treatment to post-prostatectomy recovery, while emphasizing the power of self-advocacy, family support, and destigmatizing health conversations.
Finally, they highlight the upcoming Outpacing Prostate Cancer (https://cancer.iu.edu/community/events/outpacing-prostate-cancer.html) awareness walk happening September 12th at the Scottish Rite Cathedral in Indianapolis, inviting listeners and the community to connect, raise awareness, and support life-saving research together. Tune in, know your numbers, and take charge of your health!
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6 Jul 2026
Three Brothers, Two Prostates?
Kevin and John are back to bring you some massive updates, fresh merch, and a very special guest. The brothers officially unveil the NEW Two Brothers, One Prostate logo and the upcoming merchandise store, featuring everything from hoodies to face-printed pickleball sets (where you can literally hit balls at their faces). Be sure to head over to the brand-new Two Brothers, One Prostate Facebook (https://www.facebook.com/profile.php?id=61589440547973) page to check out the logo, grab a link to the store, and join a growing community of over 300 friends!
The real chaos begins when they're joined by their brother Mike, who successfully steals the movie quote spotlight. Between debating the outdated misery of colonoscopy preps, celebrating Kevin’s upcoming grandparenthood (and his sticker shock over a $1,500 stroller), and swapping traumatizing childhood memories, this episode is a hilariously messy reminder of why you need to stay positive, keep laughing, and above all else - know your number!
15 May 2026
Two Brothers, One $1,300 Bar Tab
Kevin and John are finally together in Indiana, but the circumstances are bittersweet as they reunite to say goodbye to their cousin, Kathy. In true "Two Brothers" fashion, they find the humor in the heavy stuff by trading stories about Kathy’s Kentucky Derby-themed funeral, her "no-nonsense" legacy as a probation officer, and a legendary $1,300 wedding bar tab.
Between the laughs and a few emotional moments over an Irish blessing, the guys get back to their main mission: urging everyone to quit stalling on those blood tests. It’s a raw, heartfelt episode that moves from "gnawing on ham hocks" to a botched live Movie Quote of the Week, serving as a messy reminder that while life is short, you'd better make sure you actually live it.
22 Apr 2026
One Guest, One Hit Song
Kevin and John welcome their first-ever guest, prostate cancer survivor and advocate Brett Steffey. Brett joins the brothers to share his personal journey and reinforce a vital message: prostate cancer isn't just an "old man's disease" - it's a conversation every man over 40 needs to have.
Between the serious talk, the brothers always find a way to bring the humor back to the conversation with a look at questionable new merchandise, a hilarious original song tribute, and the weekly movie quote challenge.
From navigating the Rocky moments of life to staying positive through hormone therapy and health checkups, this episode is a rowdy, heartfelt reminder that resilience is the best medicine.
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13 Mar 2026
Two A-Cups, One Waterslide
This week, Kevin and John celebrate a major milestone as John reveals a PSA score of 0.04, proving that while the road to recovery is a "waterslide," it’s finally pointing in the right direction.
The brothers navigate the highs and lows of post-surgery life, from Kevin’s "A-cup" status and hot flashes to John’s viral-worthy TSA pat-down. Between brainstorming "unpaid" sponsorships for everything from coolers to training bras, the brothers test their movie trivia and reminisce about childhood memories.
They wrap up by looking ahead to their first-ever guest, and reminding listeners to stay positive, know your number, and live life to the fullest… with a cape.
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23 Feb 2026
17 Polyps, Zero Sponsors
Kevin and John lean into the chaos of life with cancer this week, trading medical updates and brotherly roasts while continuing their hunt for the perfect podcast sponsor. From nostalgic childhood stories to movie quotes, the brothers share an honest look at the reality of doctor visits and the importance of early testing. This episode is a funny, heartfelt reminder to keep a positive attitude and stay on top of your health.
Key Topics Covered:
The Search for Sponsors: Moving on from "Cuties" to pitch the National Grapefruit Council and Morton's Water Softener Salt
Deciphering Doctor Speak: The struggle of trying to read medical reports and PET scan results
17 Polyps: Why John holds the "record" for colonoscopy results and the importance of early prep
"Relax, It's a Blood Test": Breaking down the Super Bowl ad
RelaxItsABloodTest.com (http://relaxitsabloodtest.com/)
Superhero Capes: The story behind Kevin's new office decor and staying positive during clinical trials
Jersey Nostalgia: A look back at childhood snow days, Catholic school, and family stories
The Movie Quote Game: John tries to redeem his trivia reputation with a classic 80s flick
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10 Feb 2026
Two Knuckleheads, One Tangerine
Welcome to the debut episode of Two Brothers, One Prostate, where health meets hilarity. Join brothers, Kevin and John McDonald, as they share their prostate cancer journeys. Their goal is to educate, entertain, and empower men and their loved ones facing similar battles, with a dose of positivity, humor and real talk.
Key Topics Covered:
Kevin & John’s personal diagnoses: similarities and differences in their journeys
The significance of PSA testing and early detection
Experience with MRI, biopsy, and treatment options
Managing side effects of hormone therapy and surgery
The importance of a support network and mental health
Encouraging men to stay vigilant and get tested regularly
The power of positivity and laughter in battling cancer
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