U labu je podkast u kojem trojica hemičara različitih stavova, interesovanja i stručnosti razgovaraju o nauci čak i kad ne razgovaraju o njoj. Ponekad imamo goste, ponekad ne, ponekad nam neko fali, a jednom je Miloš sam snimio epizodu (i nije se proslavio).
Podcast Overview
U labu je podkast u kojem trojica hemičara različitih stavova, interesovanja i stručnosti razgovaraju o nauci čak i kad ne razgovaraju o njoj. Ponekad imamo goste, ponekad ne, ponekad nam neko fali, a jednom je Miloš sam snimio epizodu (i nije se proslavio).
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Publishing Since
3/26/2023
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Recent Episodes
May 24, 2026
Koronavirus – prepoznavanje preko MDA5
<p>U labu 110 (s04e30)</p><p><br></p><p>Snimljeno: 2026-05-22</p><p>Mesto: Departman za hemiju, biohemiju i zaštitu životne sredine, PMF NS</p><p>Autori: Srđan i Miloš</p><p><br></p><p><a href="https://linktr.ee/ulabu" target="_blank" rel="ugc noopener noreferrer">U labu</a></p><p><a href="https://discord.gg/J5ZwstequU" target="_blank" rel="ugc noopener noreferrer">Discord</a></p><p><br></p><p>Beleške:</p><p><br></p><p>02:10 Uvod 1: rekapitulacija dosadašnjih epki o imunitetu, naročito one o ulasku virusa u ćeliju</p><p>09:15 Uvod 2: građenje DMV čestica</p><p>12:20: MDA5 - Melanoma Differentiation-Associated protein 5</p><p>RLR - RIG-I-Like Receptors</p><p>RIG-I - Retinoic acid-Inducible gene I</p><p>TLR - Toll-Like Receptors</p><p>CARD - Caspase Recruitment Domain</p><p>26:00 MAVS - Mitochondrial antiviral-signaling</p><p>30:15 TRAF3 - Tumor necrosis factor Receptor-Associated Factor 3</p><p>Ubikvitin i razgradnja proteina, kao i paralelna uloga ubikvitinacije u imunitetu (K63 ubikvitinacija)</p><p>37:05 TBK1 - TANK-binding kinase 1</p><p>TANK - TRAF gamily member-Associated NF-Kappa B activatorKinaze kao važne farmaceutske mete</p><p>Fosforilovanje kao način kontrole kinaznog supstrata (često proteina)</p><p>42:55 IRF3 - Interferon Regulatory Factor 3</p><p>45:40 IFN-β - InterFeroN Beta</p><p>Citokini kao posebni ćelijski glasnici različiti od hormona i neurotransmitera</p><p>NF-κB - Nuclear Factor kappa-light-chain-enhancer of activated B cells</p><p>50:10 Rekapitulacija puta, završni komentari najava priče o NF-κB</p><p><br></p><p><a href="https://tinyurl.com/s04e30MDA5" target="_blank" rel="ugc noopener noreferrer">Reference</a> (ažuriraćemo)</p>
May 17, 2026
Gastrointestinalni kanceri i AdResCanCER COST akcija - dr Luka Bočkor i MSc Anja Bošnjaković
<p>U labu 109 (s04e29)</p><p><br></p><p>Gosti:</p><p><a href="https://inantro.hr/profili-zaposlenika/dr-sc-luka-bockor/" target="_blank" rel="noopener noreferer">dr. Luka Bočkor</a></p><p><a href="https://inantro.hr/en/staff-profiles/anja-bosnjakovic-2/" target="_blank" rel="noopener noreferer">MSc Anja Bošnjaković</a></p><p><a href="https://www.cost.eu/actions/CA24162/#tabs+Name:Description" target="_blank" rel="noopener noreferer">AdResCanCER COST Action CA24162</a></p><p><br></p><p>Snimljeno: 2026-05-05 (otprilike)</p><p>Mesto: Zadar</p><p>Autori: Srđan, Brane i Miloš</p><p><br></p><p><a href="https://linktr.ee/ulabu" target="_blank" rel="noopener noreferer">U labu</a></p><p><a href="https://discord.gg/J5ZwstequU" target="_blank" rel="noopener noreferer">Discord</a></p><p><br></p><p>Beleške:</p><p><br></p><p>01:30 Uvod, vreme, Zadar</p><p>02:20 Gosti, AdResCanCER, Insritut za antropologiju</p><p>06:10 Biološka antropologija</p><p>09:50 COST akcije</p><p>12:20 Šta su završili Luka i Anja</p><p>12:55 Tim koji se bavi kolorektalnim karcinomom</p><p>16:30 Gastrointestinalni kanceri</p><p>18:30 Rezistencija kancera</p><p>20:30 Gastrointestinalni kanceri su podmukli jer su im simptomi prigušeni/generički</p><p>22:00 GI trakt je povezan sa krvnim/limfnim sistemom, pa GI kanceri lako metastaziraju</p><p>22:45 Dalmatinska pršuta i kancerogenost</p><p>24:05 Srđan i COST akcija, rezistentnost, DAADRAC</p><p>28:15 Finansiranje COST akcija, STSM, broj zemalja u AdResCanCER, Vatikan</p><p>33:35 Uzimanje uzoraka iz klinika i uvođenje metoda u kliniku</p><p>38:45 Šta Anja kao data scientist radi, obrada sirovih rezultata korišćenjem odgovarajućih biblioteka u Pythonu</p><p>43:20 Gledaju se lipidi, ciljani mali molekuli...</p><p>44:55 Cena masenog spektrometra, održavanje je problem</p><p>46:40 AdResCanCER</p><p>48:40 Odjava</p><p><br></p><p><a href="https://tinyurl.com/s04e28epigen" target="_blank" rel="noopener noreferer">Reference</a></p>
May 10, 2026
Epigenetika, dijabetes i kancer - dr Melita Vidaković, dr Aleksandra Uskoković i dr Ana Sarić
<p>U labu 108 (s04e28)</p><p><br></p><p>Gošće:</p><p>dr. <a href="https://www.ibiss.bg.ac.rs/sr-yu/molekularna-biologija/saradnici/3975-dr-melita-vidakovic" target="_blank" rel="noopener noreferer">Melita Vidaković</a></p><p>dr <a href="https://www.ibiss.bg.ac.rs/sr-yu/molekularna-biologija/saradnici/3967-dr-aleksandra-uskokovic" target="_blank" rel="noopener noreferer">Aleksandra Uskoković</a></p><p>MSc <a href="https://www.ibiss.bg.ac.rs/sr-yu/molekularna-biologija/saradnici/3965-ana-saric" target="_blank" rel="noopener noreferer">Ana Sarić</a></p><p><br></p><p>Snimljeno: 2026-05-05 (otprilike)</p><p>Mesto: Zadar</p><p>Autori: Srđan, Brane i Miloš</p><p><br></p><p><a href="https://linktr.ee/ulabu" target="_blank" rel="noopener noreferer">U labu</a></p><p><a href="https://discord.gg/J5ZwstequU" target="_blank" rel="noopener noreferer">Discord</a></p><p><br></p><p>Beleške:</p><p><br></p><p>01:30 Uvod</p><p>02:50 Gošće, IBISS, 300 zaposlenih, 14 odeljenja</p><p>05:50 Odeljenje za molekularnu biologiju</p><p>06:35 Ozempic</p><p>07:45 T1D vs T2D</p><p>10:40 Ekstrakti protiv T1D</p><p>11:20 Epigenetika</p><p>14:55 Kratko o razvoju (epi)genetike u 21. veku</p><p>17:05 Epigenetika vs T1D</p><p>19:10 Stem vs somatske ćelije</p><p>20:30 Zaključavanje ARX gena</p><p>22:25 Metilacija i CRISPR-Cas (Cas/makaze treba da bude inaktiviran)</p><p>24:05 Metilacija citozina (CpG)</p><p>26:05 Selektivnost</p><p>26:55 Ubeđivanje alfi da postanu bete, model: miš</p><p>28:45 Epigenetika protiv drugih bolesti, regulativa</p><p>30:25 Trostruko negativni karcinom dojke (TNBC)</p><p>32:45 Ana pokušava da pomoću CRISPR-Cas ubedi TNBC ćelije da razviju mete koje zatim možemo da gađamo postojećim terapijama (PARP inhibitorima)</p><p>35:00 PARP</p><p>36:40 Apoptoza vs nekroza</p><p>37:50 Dopremanje CRISPR-Cas epigenetičke terapije do ćelija pankreasa</p><p>40:05 Rezistencija kancera dojke</p><p>40:50 Protokoli lečenja kancera, trka sa rezistencijom</p><p>42:10 Metilacija/demetilacija</p><p>43:40 Hemijsko modifikovanje histona, odnosno proteina (ne samo DNK)</p><p>45:30 Mapiranje (epi)genetike, značaj širine ekspertize</p><p>46:50 Šta gošće rade u labu</p><p>48:30 Struja i Cas9</p><p>49:30 Ko pravi CRISPR-Cas</p><p>50:20 dr Tomasz Jurkowski</p><p>51:40 BH/B je kul</p><p>52:30 Iskustva i perspektive sa COST akcijama Evropske unije</p><p>55:30 Saradnja unutar IBISS-a - btw. slušajte Biologiranje, tu je lepo mapiran institut</p><p>59:00 Predstavljanje i promocija nauke</p><p>1:00:20 Gojaznost</p><p>1:01:25 Šećer, neumerenost, šunka, lekovi, stres</p><p>1:05:35 Poruke za kraj</p><p><br></p><p><a href="https://tinyurl.com/s04e28epigen" target="_blank" rel="noopener noreferer">Reference</a> (ažuriraćemo)</p>
120 total episodes available
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