Your Genes by Design: practical genetics for women 45+.
This podcast features short episodes designed to turn complex science into everyday insight.
New episodes are currently paused while I focus on creating in-depth genomics courses and written resources to help you better understand your own genes and how you can support them.
If you’ve ever looked at lab results and felt like they didn’t fully explain what was happening in your body, you may find this helpful.
Download the free guide When “Normal” Lab Results Don’t Feel Normal, which explains how genomics adds context to bloodwork, hormone panels, and other health tests by showing how genes influence the body’s underlying processes.
Download the guide:
https://www.inspiredlivingforwomen.online/genes-and-lab-tests-guide
How Your Brain’s Energy, Clarity, and Memory Shift After 45 And the Genes That Shape It
If cognition feels different than it used to and focus feels less steady at times, this episode can help explain why. You’ll learn how: Cognitive patterns are influenced by genetics, not just ageHormonal shifts affect memory, focus, and stress toleranceMitochondrial efficiency plays a bigger role in mental clarity after 45Key genes like APOE, COMT, SOD2, and PPARGC1A shape energy use, inflammation, and cognitive resiliencePractical, biology-aligned support can improve clarity without extreme...
14 Jan 2026
How Your Genes Shape Digestion — And Why It Feels Different After 45
If digestion feels different than it used to — foods sitting heavier, more bloating, stronger reactions to stress, or less tolerance for certain fibers — this episode helps explain why. This episode explores how gut health has always been shaped by your genes, and why those patterns often become more apparent after 45 as hormonal, microbial, and digestive supports shift. You’ll learn how: Gut health is influenced by genetics Hormonal changes affect motility, microbiome balance, and dig...
31 Dec 2025
Why Estrogen Behaves Differently After 45 — And How Your Genes Shape the Experience
If your sleep feels lighter, your mood responds differently to stress, hot flashes seem unpredictable, or foods and supplements affect you in new ways, this episode helps explain what’s happening. This episode explores how estrogen behaves after 45 — not simply as a hormone that declines, but as one that shifts roles — and why genetics play a key role in how those changes are experienced. You’ll learn how: Estrogen influences more than reproduction, including inflammation, glucose balance...
17 Dec 2025
How Your Body Clears Hormones, Stress Metabolites, and Everyday Toxins After 45
If you’ve noticed that caffeine, alcohol, supplements, stress, or even fragrances affect you differently than they used to, this episode will help explain why. In this episode, Lauri explores how detox and methylation pathways work behind the scenes — and why these systems can feel more noticeable after 45 as hormones and genetics interact differently than before. You’ll learn how: Detox and methylation function as daily biological systems, not cleanses Estrogen changes increase the impo...
3 Dec 2025
How Your Genes Impact Overnight Glucose Regulation and Sleep Patterns After 45
If your morning glucose feels higher than expected — or your energy shifts dramatically depending on how well you slept — this episode will help connect the dots. In the final episode of the Glucose & Insulin by Design series, Lauri breaks down how sleep, cortisol, and genetics work together to shape your overnight glucose rhythm. You’ll learn how: Nighttime cortisol affects your morning glucoseSleep stages influence insulin sensitivity and recoveryMidlife hormone changes reshape your st...
19 Nov 2025
Your Stress-Clearing Gene — How COMT Shapes Cortisol, Glucose, and Energy After 45
If your energy feels unpredictable — steady one day, wired or restless the next — stress chemistry could be the reason. In this episode of Your Genes by Design, we look at how cortisol responds to everyday pressure, why that response changes after 45, and how your COMT type shapes the way your body clears stress signals and resets. You’ll discover how: • Cortisol frees up glucose any time your brain senses pressure • Slow or prolonged stress chemistry can keep glucose elevated • Estrogen f...
12 Nov 2025
The Cortisol Curve — How Stress & Genetics Shape Glucose and Energy After 45
If your energy feels unpredictable — steady one day, scattered the next — cortisol could be the reason. In this episode of Your Genes by Design, we explore how cortisol sets your body’s daily rhythm, why that rhythm often shifts after 45, and how your genetic makeup influences recovery, metabolism, and glucose control. You’ll discover how: • Cortisol acts as the body’s natural rhythm regulator • Chronic stress can flatten the daily energy curve • Midlife hormone shifts amplify spikes and cra...
5 Nov 2025
Metabolic Flexibility: How Your Body Balances Glucose and Fat After 45
Energy isn’t just about what you eat — it’s about how easily your body switches between glucose and fat for fuel. In this episode, we explore metabolic flexibility — the ability to shift between fuel sources — and why that flexibility becomes more important after 45. You’ll hear how genes like PPARGC1A, FADS1, FADS2, and ADIPOQ shape insulin sensitivity, energy stability, and how efficiently your cells use the fuel you already have. If you’ve noticed more hunger between meals, afternoon dips,...
29 Oct 2025
Oxygenation: The Missing Link Between Energy, Glucose, and Genes
Feeling steady energy isn’t luck — it’s the result of how efficiently your cells use oxygen to turn fuel into power. In this episode, we trace the path from breath to mitochondria to blood sugar, showing how oxygenation influences glucose and insulin balance after 45. You’ll hear how genes like PPARGC1A, SOD2, and NOS3 shape mitochondrial function, antioxidant defense, and blood flow — and why those factors can make the difference between clean, steady energy and afternoon crashes. If y...
22 Oct 2025
Unraveling Glucose and Insulin: Easy-to-Understand Insights
Glucose and insulin come up often in health conversations, but many of us were never really taught how they work together. Once you understand that connection, things like mid-afternoon crashes and sudden cravings start to make a lot more sense. In this episode, we look at the glucose–insulin relationship in simple, practical terms — and how genes like TCF7L2, FADS1, and PPARGC1A can influence how your body handles carbs, fats, and energy after 45. You’ll hear why two people can eat the same ...
15 Oct 2025
Stronger Cravings After 45? Here’s What Your Body’s Trying to Tell You
Cravings after 45 aren’t about willpower — they’re signals. As estrogen and cortisol shift, your body’s glucose and reward systems shift with them, making familiar habits feel harder to break. In this first episode, we look at what’s really driving those cravings and how genes like FTO, MC4R, DRD2 / DRD4, and COMT influence hunger, fullness, and reward. You’ll also hear simple ways to interrupt the craving loop and respond to what your body actually needs. If you’ve noticed stronger cravings,...
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