Axial partners with great founders and inventors. We invest in early-stage life sciences companies such as Appia Bio, Seranova Bio, Delix Therapeutics, Simcha Therapeutics, among others often when they are no more than an idea. We are fanatical about helping the rare inventor who is compelled to build their own enduring business. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company. We are excited to be in business with you — email us at info@axialvc.com
Axial Inventors
Claim This Podcastby Axial
5.0(2 reviews)
6 episodes
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Podcast Overview
Axial partners with great founders and inventors. We invest in early-stage life sciences companies such as Appia Bio, Seranova Bio, Delix Therapeutics, Simcha Therapeutics, among others often when they are no more than an idea. We are fanatical about helping the rare inventor who is compelled to build their own enduring business. If you or someone you know has a great idea or company in life sciences, Axial would be excited to get to know you and possibly invest in your vision and company. We are excited to be in business with you — email us at info@axialvc.com
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Publishing Since
6/17/2024
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Recent Episodes
September 28, 2024
Scientist Stories: Fabian Theis, Machine Learning and Systems Biology
<p>Fabian Theis conducts research in the field of computational biology. The main focus of his work is the application of machine learning methods to biological questions, in particular as a means of modeling cell heterogeneities on the basis of single cell analyses and also of integrating “omics” data into systems medicine approaches. Professor Theis received PhD degrees in physics and computer science in 2002 and 2003 respectively. After working as a postdoc in Regensburg, Tokyo and Tallahassee, he took up a position as Bernstein Fellow at the Max Planck Institute for Dynamics and Self-Organization in Göttingen. He then joined the German Research Center for Environmental Health, Helmholtz Zentrum München, where he was a group leader at the Institute for Bioinformatics and Systems Biology for six years. In 2009 he was became an Associate Professor at the Chair of Applied Mathematics, TUM. Since 2013 he has been a Full Professor of biomathematics at TUM, where he holds the Chair of Mathematical Modeling of Biological Systems, and director of the Institute of Computational Biology at the Helmholtz Zentrum München. https://scholar.google.com/citations?user=sqWpn2AAAAAJ&hl=en Axial Newsletter: https://axial.substack.com/ Build with Axial: https://build.axialvc.com/ https://linktr.ee/axialxyz</p>
July 10, 2024
Scientist Stories: Jay Shendure, Advances in Genomics
<p>Jay Shendure is a pioneer and leader in genomics who has developed new technologies that make DNA sequencing faster, cheaper, and more useful—work that is transforming genetics and medicine. Shendure’s innovations began with his doctorate in 2005, when he co-developed one of the first methods for massively parallel or next-generation DNA sequencing. After starting his own lab, he quickly advanced the technology to enable targeted sequencing of the exome—the genome’s protein-coding regions—a technique which is now in use by labs around the world and has resulted in deep catalogs of human genetic variation. In the process, Shendure showed how the technology can be used to identify genes that cause rare diseases, a strategy that has yielded hundreds of new gene discoveries. In 2012, Shendure’s lab introduced technologies that the reconstruction of the genome of a human fetus using “cell-free DNA,” obtained non-invasively from the parents. In 2016, they showed how patterns in cell-free DNA could potentially be used as part of a non-invasive cancer test. The Shendure lab’s most recent innovations include technologies for measuring the gene expression, the epigenome, and the ancestral histories of vast numbers of single cells in developing organisms. Collectively, the techniques and ongoing discoveries by Shendure and his lab hold great promise for advancing basic science and improving human health. https://en.wikipedia.org/wiki/Jay_Shendure Axial Newsletter: https://axial.substack.com/ Build with Axial: https://build.axialvc.com/ https://linktr.ee/axialxyz</p>
July 10, 2024
Scientist Stories: Leroy Hood, Systems Biology
<p>A world-renowned scientist and recipient of the National Medal of Science in 2011, Dr. Leroy Hood co-founded the Institute for Systems Biology (ISB) in 2000, served as its first President from 2000-2017 and is a Professor and Chief Strategy Officer. In 2016, ISB affiliated with Providence where Dr. Hood now serves as Emeritus Science Advisor. He is a member of the National Academy of Sciences, the National Academy of Engineering, and the National Academy of Medicine. Of the more than 6,000 scientists worldwide who belong to one or more of these academies, Dr. Hood is one of only 20 people elected to all three. He received his MD from Johns Hopkins University School of Medicine and his PhD in biochemistry from Caltech. Dr. Hood was a faculty member at Caltech from 1967-1992, serving for 10 years as the Chair of Biology. During this period, he and his colleagues developed four sequencer and synthesizer instruments that paved the way for the Human Genome Project’s successful mapping and understanding of the human genome. He and his students also deciphered many of the complex mechanisms of antibody diversification. In 1992, Dr. Hood founded and chaired the Department of Molecular Biotechnology at the University of Washington, the first academic department devoted to cross-disciplinary biology. Dr. Hood is currently carrying out studies in Alzheimer’s Disease, cancer, and wellness. He is pioneering a 1 million patient genome/phenome project, and is bringing scientific (quantitative) wellness to the contemporary U.S. health care system. Dr. Hood has played a role in founding 15 biotechnology companies including Amgen, Applied Biosystems, Arivale, and Nanostring. He has co-authored textbooks in biochemistry, immunology, molecular biology, genetics, and systems biology. In addition to having received 18 honorary degrees from prestigious universities in the U.S. and abroad, Dr. Hood has published more than 850 peer-reviewed articles and currently holds 36 patents. Dr. Hood is the recipient of numerous national and international awards, including the Lasker Award for Studies of Immune Diversity (1987), the Kyoto Prize in advanced technology (2002), the Heinz Award for pioneering work in Systems Biology (2006), the National Academy of Engineering Fritz J. and Delores H. Russ Prize for developing automated DNA sequencing (2011), and the National Academy of Science Award for Chemistry in Service to Society (2017). https://en.wikipedia.org/wiki/Leroy_Hood Axial Newsletter: https://axial.substack.com/ Build with Axial: https://build.axialvc.com/ https://linktr.ee/axialxyz</p>
6 total episodes available
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