Hear from the leading dermatologists and experts as they discuss the hottest topics in dermatology. Tune in for clinical practice tips and treatment pearls you can implement quickly and efficiently into your busy practices!
Derms and Conditions
Claim This Podcastby Dermsquared
5.0(19 reviews)
160 episodes
Updated Daily
Accepts GuestsHas Sponsors
46
Podcast Authority
BetaFairBased on show quality, social media presence, reviews, charts, and more
Quality72
Social0
YouTube0
Engagement51
Podcast Overview
Hear from the leading dermatologists and experts as they discuss the hottest topics in dermatology. Tune in for clinical practice tips and treatment pearls you can implement quickly and efficiently into your busy practices!
Language
🇺🇲
Publishing Since
3/16/2021
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46
Podcast Authority
BetaFairBased on show quality, social media presence, reviews, charts, and more
Quality72
Social0
YouTube0
Engagement51
7
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2
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10
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excellent
Episode Length
27 minutes
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good
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Every 13 days
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Recent Episodes
July 30, 2026
Translating Cytokine Soup to Clinical Practice: Untangling the Confusion
In this episode of Derms and Conditions, host James Q. Del Rosso, DO, welcomes Jason Hawkes, MD, MS, for a special Tea with Dr. D edition exploring the immunology that underpins inflammatory skin disease and how a deeper understanding of cytokine biology can inform clinical decision-making. The discussion begins by challenging the common tendency to classify diseases according to a single "dominant" cytokine or immune pathway. Drs Del Rosso and Hawkes emphasize that while frameworks such as type 1, type 2, and type 3 inflammation are valuable for organizing complex biology, they should be viewed as conceptual models rather than rigid categories, as immune responses are dynamic, overlapping, and highly interconnected. Using a series of educational slides, Dr Hawkes reviews how naïve T cells differentiate into distinct immune responses after interacting with antigen-presenting cells within the lymph node. He highlights 3 key cytokines that help clinicians remember the major pathways driving differentiation: IL-12 for type 1 inflammation, IL-4 for type 2 inflammation, and IL-23 for type 3 inflammation. These regulatory cytokines shape downstream immune responses that ultimately contribute to diseases such as atopic dermatitis and psoriasis. A major focus of the episode is the distinct but complementary roles of IL-4 and IL-13 in type 2 inflammation. Dr Hawkes explains why IL-4 serves as the critical regulator of type 2 immune differentiation, functioning within the lymph node to establish the broader immune response, while IL-13 plays a prominent role within peripheral tissues, particularly the skin. He also addresses the misconception that higher tissue expression necessarily indicates greater biologic importance, noting that cytokines often exert profound effects despite relatively low expression levels. Throughout the discussion, the speakers reinforce that cytokines should not be viewed in isolation. Their overlapping and synergistic effects help explain why patients can present with different clinical manifestations despite sharing common inflammatory mechanisms. Ultimately, the goal is not to identify a universally superior therapeutic target, but to understand each patient's disease biology well enough to select the therapy that best matches their clinical presentation. Tune in to the full episode to learn more about the foundations of type 1, type 2, and type 3 inflammation, the distinct roles of key cytokines in immune regulation and tissue disease, common misconceptions surrounding cytokine biology, and how a stronger understanding of immunology can support more personalized treatment decisions in everyday dermatology practice.
July 23, 2026
Anti-IL-23 Biologic Therapy: Expanding our Knowledge and Access for Patients with Psoriasis
Host James Q. Del Rosso, DO, interviews E. James Song, MD, exploring the IL-23 pathway's role in psoriasis, comparing biologic therapies, and discussing patient access and treatment expectations.
July 16, 2026
Topical Therapy for AD: How Can an AhR Agonist Make a Difference?
Host James Q. Del Rosso, DO, and Alexandra Golant, MD, explore how novel topical therapies, including AhR agonists, offer new strategies for managing atopic dermatitis flares and long-term disease control.
160 total episodes available with 15 transcripts
Recent guests on Derms and Conditions
Guests from recent episodes — sign up to see every guest that has ever appeared on this show.
E James Song
Guest
Alexandra Golant
Guest
Walter Liszewski
Guest
Melinda Gooderham
Guest
Michael Payette
Guest
Seemal R Desai
Guest
Dr James Q Del Rosso
Guest
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Frequently asked questions
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- What is Derms and Conditions?
- How often does this podcast release new episodes?
This podcast updates daily.
- Where can I listen to this podcast?
This podcast is available on 9 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.
- Does this podcast accept guests?
Yes, this podcast regularly features guests.
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