The EverHuman Podcast is where human biology meets the future of medicine, technology, and human potential.
Hosted by Dr. Christopher C. Thompson, Harvard Professor, Forbes Contributor, and Advanced Endoscopic Surgeon, the show unpacks how breakthroughs in biotechnology, digital health, and human physiology are redefining health, longevity, and performance.
From the science of metabolism, appetite, and weight regulation to advances in med-tech, genetic therapy, and human optimization, EverHuman brings a physician’s insight to the technologies transforming how we live, age, and thrive.
How Modern Weight-Loss Treatments Work and Who They Work Best For
Why do some weight-loss treatments work remarkably well for certain people, while others see little benefit? In this final episode of a five-part Forbes Health series, Dr. Christopher Thompson brings together everything we’ve learned about weight biology and translates it into action. Rather than treating weight as a simple problem of willpower or calories, this episode explores how modern medications, endoscopic therapies, and surgery target different biological mechanisms, and why matching ...
17 Dec 2025
Why Maintaining a Healthy Weight Isn’t the Same for Everyone
In this episode, Dr. Christopher Thompson explores why weight regulation isn’t the same for everyone. Drawing on his latest Forbes Health article, he explains how distinct biological patterns—known as obesity phenotypes—shape hunger, metabolism, inflammation, and treatment response. The discussion reframes weight struggles away from willpower and toward biology, setting the stage for more personalized, effective approaches to care. Forbes article link: https://www.forbes.com/sites/chris...
20 Nov 2025
Why Your Weight Set Point Rises and How It Drives Weight Gain
Episode 3 of a 5-part series on hunger, satiety, and long-term weight biology. In this episode of The EverHuman Podcast, Dr. Christopher Thompson breaks down why the body’s defended weight set-point doesn’t just hold steady and how it can drift upward over time. He explores the biological mechanisms behind this shift, including leptin resistance, insulin resistance, hormonal changes, microbiome alterations, epigenetics, reward-pathway shifts, and thermogenesis. We then look at the mode...
4 Nov 2025
Beyond Calories: How Your Body Defends Its Weight Set Point
Most people think of weight loss as simple math, calories in versus calories out. In reality, the body sees it as a survival challenge. When weight drops, powerful biological systems activate to defend your natural set point, slowing metabolism and increasing hunger to restore balance. In this episode, Dr. Christopher Thompson explains how the brain, gut, and hormones coordinate to regulate weight over time. He describes how leptin and insulin act as key hormonal signals for the body’s intern...
4 Nov 2025
What Drives Hunger and Fullness: Inside Your Body’s Appetite Control System
Every time you eat, or choose not to, your body is responding to an intricate communication network linking your gut, brain, and hormones. This episode explores how these biological systems determine when you feel hungry, how strongly you crave food, and when you feel full. Learn how gut hormones such as ghrelin, GLP-1, and PYY interact with the vagus nerve and the hypothalamus to regulate appetite, and how sleep, stress, and circadian rhythm can disrupt these signals. You’ll also discover th...
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