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Gut Questions?

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12 episodes

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Conversational interviews about the gut microbiome between good friends who also work together running DePaolo Lab and CMiST, Center for Microbiome Sciences & Therapeutics, at the University of Washington in Seattle, WA. One friend, Will, is a scientist and knows a sh*t ton about the gut microbiome. The other friend, Parker, is communications specialist for CMiST (aka a Jill-of-all-trades and right-hand man to Will). Join Parker, as she interviews her friend (since 1995) and boss (since 2015), Dr. Will DePaolo, about gut microbiome research, gut health, and nutrition.

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Publishing Since

5/25/2021

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Recent Episodes

Episode thumbnail for S1 E6: Brief wrap of season 1 and season 2 preview

July 29, 2021

S1 E6: Brief wrap of season 1 and season 2 preview

<p>In the second season of Gut Questions? Will and I get into the research and business of -biotics.  Will is going to cover probiotics, prebioitics, synbiotics, and postbiotics.  He'll give a brief overview of each and then we'll talk about how each is being researched and presented in the news and social media.  What comes across all of the news outlets, online or in print, and in our social media feeds can be pretty confusing and even misleading so, I thought I could get Will's expert take on what I find out there in the wilds of the internet.  </p> <p>If you've gut a question(s) you would like Will to answer in an upcoming episode, email me, Parker, at aparker@medicine.washington.edu or submit a questions on the podcast website, <a href="//www.yourgutquestions.com/contact"><strong>www.yourgutquestions.com/contact</strong></a></p> <p>A bunch of our websites and social media platforms:</p> <p>*******<br> Gut Questions? website <a href="https://www.yourgutquestions.com/">www.yourgutquestions.com</a><br> Gut Questions? Instagram <a href="https://www.instagram.com/gutquestions/">www.instagram.com/gutquestions/</a></p> <p>******<br> DePaolo Lab website: <a href="https://www.depaololab.com/">www.depaololab.com</a><br> DePaolo Lab Instagram: <a href="https://www.instagram.com/depaololab/">www.instagram.com/depaololab/</a><br> DePaolo Lab Twitter: <a href="https://twitter.com/depaololab">www.twitter.com/depaololab</a></p> <p>******<br> CMiST, Center for Microbiome Sciences & Therapeutics: <a href="https://www.cmistuw.org/">www.cmistuw.org</a></p> <p>******<br> Will's LinkedIn: <a href="https://www.linkedin.com/in/williamdepaolo/">www.linkedin.com/in/williamdepaolo/</a></p> <p>#microbiome<br> #gutmicrobiome<br> #guthealth<br> #sciencepodcast</p>

Episode thumbnail for S1 E5, PUFAs and infection, Part 4: Relevance to human health

July 27, 2021

S1 E5, PUFAs and infection, Part 4: Relevance to human health

<p>Episode 5, part 4 – Will talks about why the results from this study are relevant to our everyday lives.</p> <p>DePaolo Lab ultimately found that the presence of omega-6 polysaturated fatty acids (arachidonic acid was used in this project) worsens inflammation when challenged with virus or bacteria. So, a diet high in omega-6 fatty acids can weaken the immune response to a viral or bacterial infection. Will and I also get into a little discussion about immunity as well as what the lab found when looking at omega-3 fatty acids using the same assays that were used to study omega-6 fatty acids.<br> <br> DePaolo Lab ultimately found that the presence of omega-6 polysaturated fatty acids (arachidonic acid was used in this project) worsens inflammation when challenged with virus or bacteria.  So, a diet high in omega-6 fatty acids can weaken the immune response to a viral or bacterial infection.  Will and I also get into a little discussion about immunity as well as what the lab found when looking at omega-3 fatty acids using the same assays that were used to study omega-6 fatty acids.    </p> <p>To check out a figure showing the metabolic pathways of omega-6 and omega-3 visit our Gut Questions? podcast website and go to “Show Notes" → <a href="//www.yourgutquestions.com/shownotes">www.yourgutquestions.com/shownotes</a>  <br> <br> If you've gut a question(s) you would like Will to answer in an upcoming episode, email me, Parker, at aparker@medicine.washington.edu or submit a questions on the podcast website, <a href="//www.yourgutquestions.com/contact">www.yourgutquestions.com/contact</a></p> <p>A bunch of our websites and social media platforms:</p> <p>******* <br> Gut Questions? website <a href="https://www.yourgutquestions.com/">www.yourgutquestions.com</a><br> Gut Questions? Instagram <a href="https://www.instagram.com/gutquestions/">www.instagram.com/gutquestions/</a></p> <p>****** <br> DePaolo Lab website: <a href="https://www.depaololab.com/">www.depaololab.com</a><br> DePaolo Lab Instagram: <a href="https://www.instagram.com/depaololab/">www.instagram.com/depaololab/</a><br> DePaolo Lab Twitter: <a href="https://twitter.com/depaololab">www.twitter.com/depaololab</a></p> <p>****** <br> CMiST, Center for Microbiome Sciences & Therapeutics: <a href="https://www.cmistuw.org/">www.cmistuw.org</a></p> <p>****** <br> Will's LinkedIn: <a href="https://www.linkedin.com/in/williamdepaolo/">www.linkedin.com/in/williamdepaolo/</a></p> <p>#microbiome <br> #gutmicrobiome <br> #guthealth <br> #PUFAS <br> #polyunsaturated <br> #fattyacids <br> #sciencepodcast</p>

Episode thumbnail for S1 E5, PUFAs and infection, Part 3: Details of omega-6 fatty acid (arachidonic acid)

July 27, 2021

S1 E5, PUFAs and infection, Part 3: Details of omega-6 fatty acid (arachidonic acid)

<p>In the this part of the PUFA episode, Will explains the growth and virulence changes of Yersinia enterocolitica under room and body temperatures.  In essence, omega-6 fatty acids (arachidonic acid was used in this project) change the pathogenesis of the yersinia creating a more virulent bug.  Again, the the lab wanted to determine if infection rate or severity is increased when omega-6 fatty acids are in the system at room and body temperatures.  So, pay attention to the temperature talk at the beginning of this part because it is key to this project.  It's pretty fascinating.</p> <p><strong>Important numbers:<br> </strong>• 68-77 - room temperature (celsius), the temperature at which Yersinia enterocolitica typically grows<br> • 37 - body temperature (celsius), which Yersinia enterocolitica can survive in with the presence of omega-6 fatty acid (arachidonic acid)</p> <p>To check out a figure showing virulence factor expression of Yersinia enterocolitica at room and body temperature (paper is posted as well for anyone who really wants to deep dive into Y. enterocolitica) visit our Gut Questions? podcast website and go to “Show Notes" → <a href="https://www.yourgutquestions.com/shownotes">https://www.yourgutquestions.com/shownotes</a> </p> <p>If you've gut a question(s) you would like Will to answer in an upcoming episode, email me, Parker, at aparker@medicine.washington.edu or submit a questions on the podcast website, <a href="//www.yourgutquestions.com/contact">www.yourgutquestions.com/contact</a></p> <p>A bunch of our websites and social media platforms:</p> <p>*******<br> Gut Questions? website <a href="https://www.yourgutquestions.com/">www.yourgutquestions.com</a><br> Gut Questions? Instagram <a href="https://www.instagram.com/gutquestions/">www.instagram.com/gutquestions/</a></p> <p>******<br> DePaolo Lab website: <a href="https://www.depaololab.com/">www.depaololab.com</a><br> DePaolo Lab Instagram: <a href="https://www.instagram.com/depaololab/">www.instagram.com/depaololab/</a><br> DePaolo Lab Twitter: <a href="https://twitter.com/depaololab">www.twitter.com/depaololab</a></p> <p>******<br> CMiST, Center for Microbiome Sciences & Therapeutics: <a href="https://www.cmistuw.org/">www.cmistuw.org</a></p> <p>******<br> Will's LinkedIn: <a href="https://www.linkedin.com/in/williamdepaolo/">www.linkedin.com/in/williamdepaolo/</a></p> <p>#microbiome<br> #gutmicrobiome<br> #guthealth<br> #PUFAS<br> #polyunsaturated<br> #fattyacids<br> #sciencepodcast</p>

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What is Gut Questions??: Conversational interviews about the gut microbiome between good friends who also work together running DePaolo Lab and CMiST, Center for Microbiome Sciences & Therapeutics, at the University of Washington in Seattle, WA.

One friend, Will, is a scientist and knows a sh*t ton about the gut microbiome. The other friend, Parker, is communications specialist for CMiST (aka a Jill-of-all-trades and right-hand man to Will). Join Parker, as she interviews her friend (since 1995) and boss (since 2015), Dr. Will DePaolo, about gut microbiome research, gut health, and nutrition.
How often does this podcast release new episodes?: This podcast updates daily.
Where can I listen to this podcast?: This podcast is available on 4 platforms including Apple Podcasts, Spotify, and more. You can also use the RSS feed directly.
Does this podcast accept guests?: Information about guest appearances is not available.

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